Term
when graphing zero order reaction, what goes on the y axis?
y in the equation=mx+b 

Definition


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When graphing a zero order reaction, what is the x axis?
x in the equation y=mx+b 

Definition


Term
definition of y intercept 

Definition
the point on the y axis where x =0 


Term
how do you determine C_{0} (initial concentration) from a graph of a zero order reaction? 

Definition
C_{0} is the yintercept in a zero order reaction 


Term
in the equation y=mx+b, which factor is C0 (initial concentration) _{ } in a zero order reaction 

Definition


Term
how do you determine rate constant (K) from a graph of a zero order reaction? 

Definition
 use two points from the line (as far apart from each other as possible) to determine the slope
 multiply the slope by 1
This is because in the equation y=mx+b, m=k



Term
in the equation y=mx+b, what is the value of m in a zero order reaction? 

Definition
m=k
in other words, the slope equals the rate constant * 1 


Term
definition of half life (t_{1/2}) 

Definition
the time when original concentration is reduced to one half the original concentration 


Term
zero order half life is dependent on... 

Definition
zeroorder rate constant
initial concentration 


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Definition


Term
what is the value of t_{1} when C_{1} is initial concentration ? 

Definition


Term

Definition


Term
dC/dt=(K)(C)^{n}
what is n? 

Definition
the order of reaction
the value is 1 for first order
and 0 for zero order 


Term
conversion factor from natural log (ln) to log 

Definition


Term
a plot of ln C versus Time that exhibits a linear relationship represents... 

Definition


Term
In a plot of lnC versus time (first order kinetics) , how do you determine the concentration at a particular time? 

Definition
take the inverse ln of the y axis value for that time 


Term
In a plot of lnC versus time (first order kinetics), how do you determine the time of a particular concentration? 

Definition
take the ln value of the given concentration. then look at the graph for the corresponding value on the x axis 


Term
what is the yintercept of a first order reaction graph (lnC vs. time) 

Definition


Term
how do you determine initial concentration (C_{0}) of a first order reaction graph (lnC vs. time) 

Definition
1. plot all given values
2. make a straight line through the points
3.back extrapolate the line so that it crosses the y axis
4. take the inverse ln of the value of the y intercept 


Term
How do you determine C_{0 }(initial concentration) from a logC vs. time graph of first order kinetics 

Definition
1. plot all given values
2. make a straight line through the points
3.back extrapolate the line so that it crosses the y axis
4. take the inverse log of the value of the y intercept 


Term
in a first order reaction graph with a plot of logC vs. time, what is the formula for the value of m (the slope)? 

Definition


Term
how do you determine K in a first order reaction graph with a plot of log C vs. time? 

Definition
1. find the slope of line
2. multiply by 2.303



Term
formula to determine slope 

Definition
change in y over change in x 


Term
0.693/K
what is this equation for? 

Definition
to determine the half life of a first order reaction 


Term
What does D represent in the following equation?
A?
H?
ΔC?
k?
(DAKΔC)/h
when is this equation used? 

Definition
D: diffusion coefficient of the drug
A: surface area of absorbing membrane
K: partition coefficient of the drug
ΔC: concentration gradient
H: thickness of absorbing membrane
equation is used to determine the rate of absorption by passive diffusion 


Term
What is the Michaelis Menten Kinetics equation for?
([C]xV_{max})/(k_{m}+[C]) 

Definition
it is used to determine the rate of drug absorption by active transport
C: conc of drug available for absorption
V_{max}: max rate of absorption at high drug concentration
K_{m}: affinity constant of drug for the carrier 


Term
what is the constant for a given drugcarrier complex in active transport? (michaelis menten kinetics) 

Definition
both V_{max} and K_{m} are constant for a given drug carrier complex. therefore these two constnats are combined as a single constant K'
Rate of drug absorption = K' x [C] 


Term
K' is a combined constant of both... 

Definition


Term
the absorption of a drug by active transport proceeds according to ______ order kinetics when the affinity constant (K_{m}) is much greater than the concentration of drug at site of absorption (C) 

Definition


Term
when concentration of drug at the site of absorption is much greater than the affinity constant in active transport, the mechanism follows ______ order kinetics 

Definition


Term

Definition
this mechanism utilizes carriers under expenditure of energy (ATP)
the carriers bind to drug molecules and form a complex which moves accross the membrane
mechanism can proceed against a concentration gradient 


Term

Definition
a carrier mediated system with a similar mechanism to active transport. drug does not proceed against a concentration gradient 


Term
convective transport is AKA 

Definition


Term

Definition
transport of drug molecules takes place through the pores of the membrane. 


Term
"shifting of the solvent" 

Definition
the movement of the drug with the solvent through the pores in convective transport 


Term

Definition
maximal rate of absorption at high drug concentration 


Term

Definition
affinity constant of drug for the carrier 


Term

Definition
the viscosity of fluid in the pore of convective transport 


Term

Definition
thickness of the membrane 


Term
transport of charged molecules due to the formation of a neutral complex with another molecule carrying an opposite charge. 

Definition


Term
the only transport mechanism where a drug or compound does not have to be in aqueous solution to be absorbed 

Definition


Term
transport process in the absorption of small fat or oil droplets and small solid particles 

Definition


Term
gastric emptying appears to follow _____ order kinetics 

Definition
first.
as volume of ingested material increases, there is an initial increase in the rate of emptying gastric contents 

