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Biology Midterm Test March 2007
Practice Midterm
47
Biology
Undergraduate 1
03/05/2011

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Cards

Term
All cells have a membrane potential. true or false?
Definition
true
Term
What is gray matter?
Definition
The site of neuronal integration
Term
After an action potential, the resting potential is restored by what?
Definition
the opening of voltage-sensitive potassium channels and the closing of sodium activation gates
Term
Saltatory conduction
Definition
conduction of impulses along myelinated nerve fibers
Term
Where do synaptic vesicles discharge their contents by exocytosis?
Definition
presynaptic membrane
Term
Neurotransmitters are released from presynaptic axon terminals into the synaptic cleft by which mechanism?
Definition
exocytosis
Term
Explain the 5 steps of transmission at a chemical synapse 
Definition

1. Action potential depolarizes the synaptic terminal membrane

2. Ca2+ ions rush into neuron's cytoplasm

3. Synaptic vesicles release neurotransmitter into the synaptic cleft

4. Neurotransmitter binds with receptors associated with the postsynaptic membrane.

5. Ligand-gated ion channels open

Term
Give two examples of activities associated with the parasympathetic divisions of the nervous system.
Definition
Rest and digestion
Term

Which of the following are incorrectly paired?

forebrain-diencephalon

forebrain-cerebrum

midbrain-brainstem

midbrain-cerebellum

brainstem-pons

Definition
midbrain-cerebellum...cerebellum is part of the metacephalon
Term
What nervous system is the Motor Cortex part of ?
Definition
Cerebrum
Term
Which disease or disorder is caused by the death of brain neurons that release dopamine?
Definition
Parkinson's disease
Term
Name 4 parts of the cytoskeleton. 
Definition

micotubules

microfilaments

intermediate filaments

actin

NOT NUCLEAR ENVELOPE

Term
What structure possesses a microtubular structure similar to a basal body?
Definition
centriole (Centrioles are found at either pole of a cell during cell division. Spindle fibers attach to the centrioles at one end and chromosomes at the other end. When homologous chromosomes or sister chromatids are separated during cell division, they move towards the centrioles.)
Term

All of the following structures and proteins are directly associated with movement in cells or by cells except 

cilia

dynein

centrosomes

actin

flagella


Definition
centrosomes
Term
Plasmodesmata in plant cells are most similar in function to which structures in animal cells?
Definition
gap junctions
Term
Name the parts of the thin filaments of a muscle cell.
Definition
actin, troponin, topomyosin and a calcium binding site
Term
What is the role of calcium in muscle contractions?
Definition
to bind to the troponin complex, which leads to the exposure of the myosin binding sites
Term
Explain the steps of the excitation and contraction of a muscle cell 
Definition

1. An action potential in a motor neuron causes the axon to release acetylcholine which depolarizes the muscle cell membrane.

2. Transverse tubules depolarize the sarcoplasmic reticulum

3. Calcium is released and binds to the troponin complex

4. Tropomyosin shifts and unblocks the cross-bridge binding sites

5. The thin filaments are ratcheted across the thick filaments by the heads of the myosin molecules using energy from ATP

Term
Name four things that are included in the innate immunity that protect someone from developing a microbial infection.
Definition

skin

mucous membranes

acidic secretions

antimicrobial proteins

Term
In the inflammatory response, the absence of histamine would prevent what from happening?
Definition

dilation of arterioles

increased permeability of blood vessels

increased population of phagocytes in the area

leakage of the plasma to the affected area

Term

Which of the following are false about innate immunity?

- they include inflammatory responses

-they do not include physical and chemical barriers

-they must be primed by the presence of anitgen

-they may involve the formation of membrane attack complexes

-Macrophages and natural killer cells are participants in the process

Definition

-they DO include physical and chemical barriers

-they do not have to be primed by the presence of an antigen

Term
What are antigens?
Definition
foreign molecules that trigger the generation of antibodies
Term
Name four parts of an antibody molecule.
Definition

the constant regions (C regions)

The variable (V regions)

Light chains

Heavy chains

Term
When a person's bone marrow is destroyed by radiation which cells cannot be produced?
Definition

B cells

T cells

erythrocytes

neutrophils

 

Term
What is an important role of the MHC?
Definition
distinguishing self from nonself
Term

Which of the following about antibodies is false?

-antibodies are immunoglobulin proteins

-antibodies bind with foreign cells and lyse them

-The structure of antibodies includes both a constant and variable region

-antibodies act as signals to blood complement proteins or phagocytes

-plasma cells are responsible for the production of antibodies

Definition
antibodies bind with foreign cells and lyse them
Term
A nonfunctional CD4 protein on a helper T cell would result in the helper T cell being unable to...
Definition
interact with a class II MHC-antigen complex
Term
What is humoral immunity mounted by?
Definition
It is mounted by lymphocytes that have matured in the bone marrow
Term
What could prevent the appearance of the symptoms of an allergy attack?
Definition
blocking the attachment of the IgE antibodies to the mast cells
Term
Name four immune system disorders
Definition

AIDS

SCID

Lupus erythematosus

Multiple sclerosis 

Term
What would a person with AIDS be unlikely to suffer from?
Definition
rheumatoid arthritis (it's not a disease)
Term
The cross Ppxpp (where P=the ability to produce purple pigment and p=the inability to produce purple pigment) is an example of what type of cross?
Definition
a test cross
Term
The condition of missing one of the chromosome 21 homologues is called
Definition
aneyploidy
Term

Which of the following karyotypes would not have one or more Barr bodies visible in the nucleus?

XY male

XXY male

XX female

XXX female

XXYY male

Definition
XY male
Term
Phenylketonuria is an inherited disease caused by an autosomal recessive allele. A woman and her husband are both carriers (heterozygous) and have 3 children. What is the probability that their first child will NOT have the disease but be a carrier?
Definition
50%
Term
Phenotype
Definition
describes the physical appearance or characteristics of an organism
Term
Genotype
Definition
describes the alleles of all relevant genes of the organism
Term

40. Foreign antigens synthesized within body cells are presented by

  1. class I MHC molecules to cytotoxic T cells
  2. class II MHC molecules to helper T cells
  3. class I MHC molecules to helper T cells
  4. class II MHC molecules to CD4-bearing cells
  5. class II MHC molecules to cytotoxic T cells

Definition
a)class I MHC molecules to cytotoxic T cells
Term

  1.  
    1. proteins found in the blood that cause foreign blood cells to clump
    2. proteins embedded in B-cell membranes
    3. proteins that consist of two light and two heavy polypeptide chains
    4. antibody-generating foreign macromolecules
  2. What are antigens?

  3. Both A and C are correct.

Definition
d. antibody-generating foreign macromolecules
Term

 In the inflammatory response, the absence of which of the following would prevent all the others from happening?

  1. dilation of arterioles
  2. increased permeability of blood vessels
  3. increased population of phagocytes in the area
  4. release of histamine
  5. leakage of plasma to the affected area

Definition
release of histamine
Term

The clonal selection theory implies that

  1. related people have similar immune responses.
  2. antigens activate specific lymphocytes.
  3. only certain cells can produce interferon.
  4. memory cells are present at birth.
  5. the body selects which antigens it will respond to.

Definition
b. antigens activate specific lymphocytes.
Term

Plasma cells are

  1. immature forms of T cells.
  2. cells that produce few antibodies.
  3. the effector cells of humoral immunity.
  4. responsible for immunological memory.
  5. responsible for the phagocytosis of foreign organisms.

Definition
c. the effector cells of humoral immunity.
Term

A major difference between active and passive immunity is that active immunity requires

  1. acquisition and activation of antibodies.
  2. proliferation of lymphocytes in bone marrow.
  3. transfer of antibodies from the mother across the placenta.
  4. direct exposure to a living or simulated disease organism.
  5. secretion of interleukins from macrophages.

Definition
direct exposure to a living or simulated disease organism
Term

The function of CD4 and CD8 is to assist T cells in

  1. enhancing secretion of proteins such as interferon.
  2. activating B cells and other T cells.
  3. binding of the MHC-antigen complex.
  4. recognition of self cells.
  5. secretion of antibodies specific for each antigen.

Definition
c. binding of the MHC-antigen complex
Term

The T in T lymphocytes stands for

  1. thymus
  2. trigger.
  3. threshold.
  4. toxic.
  5. thyroid.

 

Definition
thymus
Term

Which of the following results in long-term immunity?

  1. the passage of maternal antibodies to her developing fetus
  2. the inflammatory response to a splinter
  3. the administration of serum obtained from people immune to rabies
  4. the administration of the chickenpox vaccine
  5. the passage of maternal antibodies to her nursing infant

Definition
d. the administration of the chickenpox vaccine
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