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Biology - Genetic Variation
Meiosis and Genetic Variation
31
Biology
9th Grade
02/04/2016

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Term
What are chromatids?
Definition
Identical replicated strands of DNA.
Term
How many chromosomes are found in human somatic cells?
Definition
46 (23 pairs)
Term
How many chromosomes are found in human sperm or ova?
Definition
23
Term
What are proteins associated with wrapping and folding the DNA?
Definition
histones
Term
The diploid number of chromosomes in a skunk is 50, how many chromosomes are in skunk sperm?
Definition
25
Term
What type of cell has two homologues, has chromosomes found in pairs, is designated by 2n, and is called diploid?
Definition
somatic cells
Term
What type of cell has one of each pair of homologues and is designated by the n?
Definition
gametes
Term
How are homologous chromosomes similar?
Definition
size, shape, and genetic content
Term
What process creates 4 haploid cells from a diploid cell?
Definition
meiosis
Term
What processes create new genetic combinations (recombination)?
Definition
crossing over, independent assortment, random fertilization
Term
What process creates sperm cells?
Definition
Meiosis - specifically spermatogenesis
Term
How are spermatogenesis and oogenesis different?
Definition
Spermatogenesis ends with 4 viable haploid sperm while oogenesis ends with 1 viable haploid ovum.
Term
When are homologous chromosomes separated?
Definition
Meiosis I
Term
What occurs during crossing over?
Definition
Homologous chromosomes exchange corresponding segments of DNA.
Term
When does crossing over occur?
Definition
Prophase I
Term
Where does crossing over occur?
Definition
ovaries and testes
Term
What divides unequally in oogenesis?
Definition
cytoplasm
Term
According to independent assortment, as skunk has 50 chromosomes in its diploid state, how many different variants are in their sperm or egg cells?
Definition
2n=50, n=25, n2=33,554,432 (3.4 x 107)
Term
What type of mutation involves one or a few nucleotides?
Definition
point mutation
Term
What are changes in the DNA or gene due to damage or being copied incorrectly?
Definition
mutations
Term
What effects can mutations have?
Definition
helpful, neutral, or harmful
Term
What is monosomy?
Definition
The loss of an entire chromosome
Term
What is trisomy?
Definition
The gain of an extra chromosome
Term
What type of mutations affects an organisms's offspring?
Definition
Germ cell or gamete mutations
Term
What happens when nondisjunction occurs?
Definition
A gamete will receive too many or too few homologues of a chromosome
Term
What type of mutations are insertions and deletions considered?
Definition
Frameshift mutations
Term
What is the result of nondisjunction of chromosome 21 (47 chromosomes)?
Definition
Down syndrome
Term
How does the amino acid sequence differ between a framshift and substitution mutation?
Definition
A substitution changes one amino acid in the sequence while frameshift changes every amino acid after the mutation.
Term
How do the cells produced in mitosis compare to the cells produced in meiosis?
Definition
Mitosis produces 2 identical diploid cells and meiosis produces 4 genetically variant haploid cells
Term
How does crossing over affect the genetic variation of gametes?
Definition
The genetic variability increases because alleles are traded between maternal and paternal homologues (chromatids aren't identical)
Term
What two macromolecules make up chromosomes?
Definition
DNA and protein
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