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Biology exam Ch. 3&4
Biology exam Ch. 3&4
87
Biology
Undergraduate 1
09/02/2010

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Cards

Term
Name four molecules in living organisms.
Definition
  • Proteins
  • Carbohydrates
  • Lipids
  • Nucleic acids
Term
Monomer
Definition
A small molecule, two or more of which can be combined to form oligomers or polymers.
Term
Macromolecules
Definition
polymers with molecular weights >1000. Built from monomers
Term
Polymers
Definition
A large molecule made up of similar or identical sub-units called monomers.
Term
Functional groups
Definition

Groups of atoms with specific chemical properties that are contributed when attached to larger molecules. Behavior is consistent.

Term
Seven functional groups most important in the chemistry of life...
Definition

§Hydroxyl group
§Carbonyl group
§Carboxyl group
§Amino group
§Sulfhydryl group
§Phosphate group
§Methyl group

Term
Addition of a methyl group to DNA, or to molecules bound to DNA, affects...?
Definition
gene expression
Term
Arrangement of methyl groups in male & female sex hormones affects their...?
Definition
shape and function
Term
Isomers
Definition

Molecules with same chemical formula, but atoms are arranged differently

Term
Structural isomers
Definition
isomers that have different covalent arrangements of their atoms
Term
Geometric isomers
Definition
isomers that the have same covalent arrangements but differ in spatial arrangements
Term
Enantiomers
Definition
mirror images
Term
Structural isomers
Definition
[image]
Term
Biochemical unity means?
Definition

Organisms can obtain required macromolecules by eating other organisms

Term
Polymers are formed in what kind of reactions?
Definition
Condensation(dehydration) reactions
Term
When polymers are formed what is removed and what is joined by covalent bonds?
Definition
  • Water removed
  • monomers joined by covalent bonds
Term
Polymers are broken down into monomers in what kind of reactions?
Definition
Hydrolysis reactions
Term
*What are the functions of proteins?*
Definition

 

  • Structural support
  • Protection
  • Transport
  • Catalysis
  • Defense
  • Regulation
  • Movement

 

Term
Proteins are made from how many different amino acids?
Definition
20 (monomeric units)
Term
  • Proteins consist of how many polypeptides?
  • How many types of polypeptides?
Definition
  • One or more
  • 1 or more types
Term
Chains of amino acids are folded into...?
Definition
specific three dimensional shapes
Term
Amino acids have what two groups that act as both acid and base?
Definition
carboxyl and amino groups
Term
Amino acids exist in what two isomeric forms?
Definition
  • D-amino acids (dextro,"right")
  • L-amino acids (levo, "left")
Term
Side chains are also called?
Definition
R-groups
Term
How many types of amino acids are there?
Definition
20
Term
Hydrophilic amino acids with polar but uncharged side chains form what?
Definition
hydrogen bonds
Term
Ion
Definition
An electrically charged particle that forms when an atom gains or loses one or more electrons.
Term
A functional protein consists of how many polypeptides?
Definition
one or more
Term
A sequence of amino acids determines a functional protein's what?
Definition
three-dimensional structure
Term
The structure of a functional protein determines its?
Definition
function
Term

In a polypeptide chain, which reads like a sentence:

  1. The "capital letter" is what group?
  2. The "period" is what group?
Definition
  1. the amino group of the first amino acid - N terminus
  2. the carboxyl group of the last amino acid - C terminus
Term
α helix
Definition
right-handed coil resulting from H bond every 4th aa (fibrous structural proteins)
Term
β pleated sheet
Definition
H bonds between 2 or more polypeptide chains (aligned side by side)
Term
What determines the secondary structure of a protein?
Definition
Hydrogen
Term
The primary structure of a protein consists of a sequence of what?
Definition
Amino acids
Term
The primary structure determines which other two structures of a protein?
Definition
Secondary and tertiary
Term
Tertiary structure
Definition
the relative locations in three-dimensional space of all atoms in the molecule. The overall shape of a protein.
Term
The Tertiary structure is determined by interactions of what?
Definition
R-groups
Term
What are the interactions of R-groups thaat determine the tertiary structure?
Definition

§Disulfide bonds
§Aggregation of hydrophobic side chains
§Van der waals forces
§Ionic bonds
§Hydrogen bonds

Term
Quarternary structure
Definition
The specific three-dimensional arrangement of subunits
Term
Ligan
Definition
Any molecule that binds to a receptor site of another molecule.
Term
What determines the function of a protein and allows it to bond non-covalently with another molecule?
Definition
Specific shape andd functional groups
Term
Denaturation
Definition
loss of a 3-dimensional structure & function of protein (biologically inactive)
Term
What conditions affect the secondary and tertiary structure of a protein?
Definition

 

§High temperature
§pH changes
§Salt concentration
§Other environmental factors
§High concentrations of polar molecules

 

Term
Chaperonins
Definition
proteins that guard other proteins by counteracting molecular interactions that threaten their three-dimensional structure.
Term
What helps prevent proteins from binding to wrong ligands?
Definition
Chaperonins
Term
Carbohydrates
Definition
Carbon molecules with hydrogen & hydroxyl groups
Term
What are the simplest carbohydrates?
Definition
Monosaccharides
Term
Monosaccharide
Definition
A simple sugar
Term
Monnosaccharides are classified by...?
Definition
  1. Location of carbonyl group
  2. Number of carbons in carbon skeleton
Term
  1. Monosaccharides with 3 carbons?
  2. With five carbons?
  3. With six carbons?
Definition
  1. Trioses
  2. Pentoses
  3. Hexoses
Term
Disaccharides
Definition
two simple sugars linked by covalent bonds
Term
Oligosaccharides
Definition
3 to 20 monosaccharides
Term

Polysaccharides

 

Examples...?

Definition

hundreds or thousands of monosaccharides

 

starch, glycogen, cellulose

Term

Structure & function of a polysaccharide are determined by:

Definition

Sugar monomers

Positions of glycosidic linkages

Term

what is the storage of glucose in plants?

in animals?

Definition

starch

glycogen

Term
Which polysaccharide is very stable and good for structural components?
Definition
cellulose
Term
Humans cannot digest cellulose but what can?
Definition
bacteria
Term

Carbohydrates can be modified by the addition of what functional groups?

Definition

Sugar phosphates

Amino sugars

Term
Chitin
Definition
The characteristic tough but flexible organic component of the exoskeleton of arthropods, consisting of complex, nitrogen-containing polysaccharide.
Term

Lipids

 

Definition
Nonpolar, hydrophobic molecules that include fats, oils, waxes, steroids, and the phospholipids that make up biological membranes.
Term
Triglyceride
Definition
a simple lipid in which three fatty acids are combined with molecule of glycerol
Term
Fatty acid
Definition
nonpolar hydrocarbon with a polar carboxyl group-bonds with hydroxyls of glycerol in an ester linkage
Term
Three functions of lipids
Definition
  1. Hydrophobic
  2. High energy storage
  3. protection
Term
Hydrogenation
Definition

Process of converting unsaturated fats to saturated fats by adding hydrogen

Term
  1. What is the head of a phospholipid?
  2. the tail?
Definition
  1. Hydrophilic phosphate group
  2. Hydrophobic fatty acid chains
Term
Carotenoids
Definition
light-absorbing pigments
Term
Steroid
Definition
Any of a family of lipids whose multiple rings share carbons
Term
Vitamins
Definition
Small molecules not synthesized by the body
Term
Nucleic acid
Definition
A polymer made up of nucleotides, specialized for the storage, transmission, and expression of genetic information. DNA and RNA are nucleic acid.
Term

1)What are the functions of DNA?

 

2)Functions of RNA?

Definition

1)provides directions for its own replication

directs synthesis of messenger RNA (mRNA)

 

2)mRNA controls protein synthesis

protein synthesis occurs in ribosomes

 

Term
Sugars and phosphate groups are bonded by what type of linkages?
Definition
Phosphodiester
Term

*Test question*

 

Nucleoside has no phosphate group.

 

 

Definition
Term
Purines pair with pyrimidines in what type of bonding?
Definition
H-bonding
Term
What are the four DNA bases?
Definition
  1. adenine (A)
  2. cytosine (C)
  3. guanine (G)
  4. thymine (T)
Term
Which bases pair to each other in complementary base pairing?
Definition

A−T

C−G

Term
Instead of thymine uses what base?
Definition
uracil (U)
Term

RNA is single-stranded, but complementary base pairing occurs in the structure of some types of RNA** (test)

Definition
Term

 

DNA is an informational molecule
§Information is encoded in sequences of bases
RNA uses the information
§To determine the sequence of amino acids in proteins
Definition
Term
Double helix
Definition
Refers to DNA and the (usually right-handed) coil configuration of two complimentary, antiparallel strands.
Term
DNA replication and transcription depends on...?
Definition
base pairing
Term
Genome
Definition
The complete DNA sequence for a particular organism or individual.
Term
Closest living relative of the human is the...?
Definition
Chimpanzee
Term

Roles of following nucleotides:

 

ATP

GTP

cAMP

Definition

energy transducer in biochemical reactions

 

energy source in protein synthesis

 

essential to the action of hormones & transmission of information in the nervous system

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