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Biology Chapter 9: Circulation
mcat biology
89
Biology
Undergraduate 4
06/30/2009

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Term
components of cardiovascular system
Definition
heart, blood vessels, blood
Term
portal system
Definition
blood travels through TWO capillary beds prior to returning to the heart
Term
how many portal systems are there?
Definition
3-liver (hepatic), kidneys, brain (hypophyseal)
Term
divides right atrium and right ventricle
Definition
tricuspid valve (type of atrioventricular valve)
Term
divides left atrium and left ventricle
Definition
mitral valve (type of atrioventricular valve)
Term
atrioventricular valves: between what and function
Definition
between atria and ventricles and prevent backflow of blood into atria
Term
semilunar valves: what two names
Definition
aortic valve and pulmonic valve
Term
seperates left ventricle and aorta
Definition
aortic valve
Term
separates right ventricle and pulmonary artery
Definition
pulmonic valve
Term
valves with 3 cusps:
Definition
tricuspid, aortic, pulmonic
Term
valves with two cusps
Definition
mitral vavle
Term
cardiac output
Definition
total volume of blood the left ventricle pumps per minute
Term
cardiac output (eq) =
Definition
heart rate * stroke volume
Term
heart rate
Definition
number of heart beats per minute
Term
stroke volume
Definition
volume of blood pumped out of the left ventricle per contraction
Term
location of SA node
Definition
right atrium
Term
sinoatrial node spreads impulses to
Definition
both atria--the contract simultaneously
Term
AV nodes conducts slowly because
Definition
its allowing time for atrial contraction and the ventricles to fill with blood
Term
electrical pathway of heart :)
Definition
SA--> AV-->bundle of His (AV bundle) --> right and left bundle branches --> purkinje fibers
Term
_____ innervates the heart via the vagus nerrve and causes ____
Definition
parasympathetic, decreased heart rate
Term
___ innervates via the cervical and upper thoracic ganglia and causes ____
Definition
sympathetic, increased heart rate
Term
arteries:
Definition
thick, muscular, elastic, away
Term
veins:
Definition
thin, inelastic, toward
Term
what can diffuse across capillaries?
Definition
gases, nutrients, enzymes, hormones, wastes
Term
___ circulation usually fights with gravity
Definition
venous
Term
venous blood flow depends on...
Definition
their compression by skeletal muscles during movement
Term
an antigen is...
Definition
BAD (jen is bad)
Term
antibody is...
Definition
body is good
Term
arise from stem cells in the marrow of long bones
Definition
leukocytes
Term
two important types of leukocytes
Definition
B lymphoctyes and T lymphocytes
Term
lymphocytes play a role in immune response and are involved in the production of
Definition
antibodies
Term
lymphocytes play a role in immune response and are involved in the production of
Definition
antibodies
Term
formed from stem cells in bone marrow
Definition
erythrocytes
Term
erythrocytes lack
Definition
nuclei, mito, and membranous organelles
Term
phagocytizes RBCs
Definition
spleen and liver
Term
platlets are formed in the ____ and lack___
Definition
bone marrow; nuclei
Term
macromolecules that are foreign to the host organism and trigger an immune response
Definition
antigens
Term
substances that hte immune system recognizes as foreign and mounts a response against
Definition
antigens
Term
proteins that recognize and bind to antigens
Definition
antibodies
Term
can cause the antigen to clump (agglutinate) and form large, insoluble complexes that are then removed by phagocytic cells
Definition
antibodies
Term
universal recipient
Definition
AB
Term
universal donor
Definition
O
Term
another name for antigens on RBCs
Definition
agglutinogen
Term
another name for antibodies on RBCs
Definition
immunoglobulins
Term
antigen of blood type A, antibody
Definition
A, anit-B
Term
antigen of blood type B, antibody
Definition
B, anti-A
Term
antigen of blood type AB, antibody
Definition
A and B, none
Term
antigen of blood type O, antibody
Definition
none, anti-A, anti-B
Term
___ antibodies cannot cross the placenta
Definition
anti-A and anti-B
Term
erythroblastosis fetalis
Definition
severe anemia for fetus bc of Rh factor
Term
clotting factor
Definition
thromboplastin
Term
two specific defense mechanisms of immune system:
Definition
1. humoral immunity 2. ell-mediated immunity
Term
specific defense that involves the production of anitbodies after exposure to antigens
Definition
humoral immunity
Term
specific defense that involves cells that bomat fungal and viral infection
Definition
cell-mediated immunity
Term
responsible for both specific immune responses
Definition
lymphocytes
Term
region of antibody that binds to antigen
Definition
variable region
Term
region of antibody that contains a disulfide bridge
Definition
constant region
Term
specific part of antigen that is recognized by the immune system
Definition
epitope
Term
primary response of humoral immunity:
Definition
B cells become either memory cells(long-lived in blood stream) or plasma cells
Term
memory cells are responsible for the secondary response which is
Definition
when the cells stay in the blood indefinately and have a more immediate response on exposure to the same antigen
Term
production of antibodies during an immune response
Definition
active immunity
Term
acquired either passively or by injection (ex mom to fetus)--short lived
Definition
passive immunity
Term
lymphocytes involved in cell-mediated immunity
Definition
T-cells
Term
lymphocytes involved in Humoral immunity
Definition
B cells
Term
mature and proliferate in the thymus
Definition
T cells
Term
mature and proliferate in spleen and lymph nodes
Definition
B cells
Term
types of T cells and fuctions:
Definition
1. cytotoxic-destroy antigens directly
2. helper-activate other B and T cells
3. supressor-regulate B and T cells to decrease activity

*can differentiate into memory
Term
play an important role in allergies
Definition
T cells
Term
play an important role in the rejection of organ transplants
Definition
T cells
Term
lysozyme
Definition
enzyme in tears that breaks down bacterial cell walls
Term
lymphokine
Definition
signaling molecule involved in coordination of immune response
Term
histamine
Definition
secreted by damaged cells that causes blood vessel dialation
Term
nonspecific defense mechanisms
Definition
1. skin
2. passages
3. macrophages
4. inflammatory response
5. interferons
Term
proteins produced by cells under viral attack that diffuse to other cells where they help prevent the spread of the virus
Definition
interferons
Term
activate cytotoxic T cells to kill infected cells and stimulate B cells to secrete anitbodies
Definition
interleukins
Term
specialized B cells that produce and secrete anitbodies
Definition
plasma cells
Term
T Cell Receptors
Definition
in the membrane of the T cell and only can recognize antigens on surface of other cells (not in solution) and in a specific context
Term
antigen must be presented to cell as part of a ____ in order to stimulate a T cell receptor
Definition
Major Histocompatability Complex
Term
MHC class I:
Definition
proteins on surface of cells
Term
MHC class II
Definition
proteins only present on immune cells
Term
something has to be recognized as ___ for antibodies to be produced
Definition
non-self
Term
___ have valves (not heart)
Definition
veins
*arteries and capillaries do not
Term
ductus venosus connects:
Definition
umbulical vein to vena cava
Term
ductus venosus bypasses
Definition
liver
Term
foramen ovale connects:
Definition
right and left atrium
Term
foramen ovale bypasses:
Definition
lungs
Term
ductus arteriosus connects:
Definition
pulmonary artery and aorta
Term
ductus arteriosus bypasses:
Definition
lungs
Term
pathway of exhalation
Definition
aveoli-> bronchi->trachea->larynx->pharynx
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