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| protein catalysts that accelerate reactions |
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Definition
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| are enzymes consumed in the rxn? |
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| lower activation energy of the reaction and increase the rate |
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| do enzymes affect overall delta G of the rxn? |
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| aid in binding the substrate to the enzyme or stabilize the enzyme in an active conformation |
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| enzyme without cofactor is called |
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| does the body make cofactors? |
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Definition
| no--most must be obtained from the diet |
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Term
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Definition
| concentration of enzyme and substrate, temp, ph |
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Term
| rates of enzyme catalyzed rxns double for |
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Definition
| every 10 degree C increase |
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Term
| enzymes like __ ph and ___ temp |
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| pancreatic enzymes like what ph? |
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Definition
| has two or more active sites and can be made of more than one subunit |
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Definition
| molecule other than the substrate-can bind to enzyme and stabilize a configuration |
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Definition
| allosteric inhibitors and allosteric activators |
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Definition
| stabilizes the inactive conformation |
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Definition
| stabilizes the active configuration--promotes formation of enzyme-substrate complexes |
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Definition
| 1. feedback inhibition 2. reversible 3. reversible |
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Definition
| prevents overproduction of end product |
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Term
| types of reversible inhibition |
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Definition
| competitive and non competitive inhibitors |
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Definition
| do not compete with substrate---bind to other sites and cause a conformational change--not relieved by increasing substrate concentration |
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Definition
| competes with substrate for active site--can be relieved by adding more substrate |
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Definition
| permanent damage is done to active site by either covalent bonding or changing structure of the active site |
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| inactive form of enzyme--ending in ogen |
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| enzyme specificity is determined by |
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Definition
| the unique 3D structure of the active site |
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| regulatory mechanism that serves to maintain homeostasis |
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