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Biology Ch. 3 - Embryogenesis and Development
MCAT
42
Biology
Undergraduate 1
05/25/2016

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Term
fertilization
Definition
  • the joining of the sperm and an ovum
  • sperm uses acrosomal enzymes to penetrate the corona radiata and zona pellucida
  • acrosomal apparatus is established on sperm injects its pronucleus
Term
cortical reaction
Definition
a release of calcium ions when the sperm penetrates the ovum which increases the zygote's metabolic rate and prevents additional sperm from getting in
Term
cleavage
Definition
the early divisions of cells in the embryo, in the early stages overall volume doesn't change, only the number of cells
Term
indeterminate vs determinate cleavage
Definition
cleavage that results in cells that are capable of becoming any cell in an organism vs cells that are committed to differentiating into a specific cell type
Term
morula
Definition
solid mass of cells seen in early development
Term
blastula
Definition
  • formed from blastulation
  • a hollow ball of cells with a fluid-filled inner cavity known as a blastocoel
  • known as blastocyst in mammals
  • contains trophoblast cells and the inner cell mass
Term
trophoblast cells
Definition
surround the blastocoel and give rise to the chorion and later the placenta
Term
inner cell mass
Definition

protrudes into the blastocoel and gives rise to the organism itself

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Term
placenta
Definition
forms when the blastula implants into the endometrium, nourishes and maintains fetus through umbilical cord
Term
chorion and chorionic villi
Definition
chorion is an extraembryonic membrane that develops into the placenta. It has finger like projections that burrow into the endometrium and are sites for gas exchange
Term
yolk sac
Definition
support embryo until placenta is developed
Term
amnion
Definition
thin, tough membrane that is filled with and produces amniotic fluid
Term
allantosis
Definition
involved in early fluid exchange between the embryo and the yolk sac
Term
gastrulation
Definition
the formation fo three distinct cell layers which results in a gastrula
Term
archenteron
Definition
the membrane invagination into the blastocoel that later develops into the gut
Term
blastopore
Definition
opening of the archenteron that develops into the anus in deuterostomes and the mouth in protostomes
Term
What does the ectoderm give rise to?
Definition
  • integument: epidermis, hair, nails, epithelia of nose, mouth and lower anal canal
  • lens of the eye
  • nervous system, including adrenal medulla
  • inner ear
Term
What does the mesoderm give rise to?
Definition
  • musculoskeletal system
  • circulatory
  • most of the excretory systems
  • gonads
  • muscular and connective tissue layers of the digestive and respiratory systems
  • adrenal cortex
Term
What does the mesoderm give rise to?
Definition
  • musculoskeletal system
  • circulatory
  • most of the excretory systems
  • gonads
  • muscular and connective tissue layers of the digestive and respiratory systems
  • adrenal cortex
Term
What does the endoderm give rise to?
Definition
  • epithelial lining of the digestive and respiratory tracts, including lungs
  • pancreas
  • thyroid 
  • bladder
  • distal urinary tracts
  • parts of the liver

 

Term
neurulation
Definition

development of the nervous system

  • rod of mesodermal cells, notochord, forms along the long axis of the oranism like a primitive spine
  • notochord induces a group of overlying ectodermal cells to slide inward to form neural folds
  • neural folds grow toward one another until they fuse into a neural tube which gives rise to the central nervous system
  • neural crest cells at the tip of each neural fold give rise to the peripheral nervous system
  • ectodermal cells will migrate over the neural tube and crests to cover the rudimentary nervous system
Term
notochord
Definition
rod of mesodermal cells that forms along the long axis of the organism; it induces the overlying ectodermal cells to slide inward to form neural folds (a step in neurulation)
Term
neural tube
Definition
gives rise to the central nervous system; forms when neural folds grow towards one another until they fuse
Term
neural crest cells
Definition
found at the tip of each neural fold, they migrate outward to form the peripheral nervous system
Term
teratogens
Definition
substances that interfere with development causing defects or even death of the developing embryo
Term
determination
Definition
the commitment to a specific cell lineage, which may be accomplished by uneven segregation of cellular material during mitosis or by morphogens
Term
morphogens
Definition
promote development down a specific cell line
Term
totipotent cells
Definition
able to differentiate into all cell types, including the three germ layers and placental structures
Term
pluripotent cells
Definition
able to differentiate into all three of the germ layers and their derivatives
Term
multipotent cells
Definition
able to differentiate only into a specific subset of cell types
Term
autocrine signals
Definition
act on the same cell that released the signal
Term
paracrine signals
Definition
act on cells in the local area
Term
juxtacrine signals
Definition
act through direct stimulation of the adjacent cells
Term
endocrine signals
Definition
act on distant tissues after traveling through the bloodstream
Term
apoptosis
Definition
programmed cell death
Term
regenerative capacity
Definition
ability of an organism to regrow certain parts of the body; liver has high capacity, kidney somewhat, heart none at all
Term
senescence
Definition
biological aging
Term
Which has a higher affinity for oxygen, fetal hemoglobin or adult hemoglobin?
Definition
fetal hemoglobin
Term
foramen ovale
Definition
a one way valve that connects the right atrium to the left atrium that allows blood entering the right atrium to flow into the left atrium and straight into systemic circulation avoiding the lungs
Term
ductus arteriosus
Definition
shunts leftover blood from the pulmonary artery to the aorta
Term
ductus venosus
Definition
shunts blood returning from the placenta via the umbilical vein directly to the inferior vena cava
Term
What are the two shunts used to reroute blood from the lungs in fetal circulation?
Definition

foramen ovale - connects right atrium to left atrium

ductus arteriosus - pulmonary artery to the aorta

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