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Biology 197 Section 3
Lecture #1
121
Biology
Undergraduate 2
03/19/2012

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Term
What are the 2 types of cells in the nervous system?
Definition
1)Neurons
2)Glial Cells
Term
Neurons
Definition
Generate and transmit action potentials along an axon to the synapse with another cell
Term
Nerve
Definition
A bundle of axons from different neurons
Term
Oligodendrocytes
Definition
Produce Myelin and insulate axons in the central nervous system
Term
Schwann cells
Definition
Produce Myelin and insulate axons in the peripheral nervous system
Term
Astrocytes
Definition
contribute to the blood brain barrier which protects the brain from toxic chemicals in the blood
Term
Microglia
Definition
Provide the central nervous system with immune defenses
Term
Afferent Neurons
Definition
Neural network: Carry sensory information into the nervous system
Term
Efferent Neurons
Definition
Neural network: carry commands to Physiological and behavioral effectors
-muscles & glands
Term
Interneurons
Definition
integrate and store information and
communicate between the afferent and efferent neurons
Term
Ganglia
Definition
Neural network: clusters of neurons with similar characteristics or functions
Term
Brain
Definition
Neural network: the centralized integrative center of the nervous system
Term
Spinal Chord
Definition
Neural network: site where many nerve cells are found in vertebrates (along with the brain)
Term
Central Nervous system
Definition
The brain and spinal cord
Term
Peripheral Nervous System (PNS)
Definition
Nerve cells that are not in the brain or spinal cord
Term
Synapse
Definition
A specialized type of junction where a neuron meets its target cell and passes information along
Term
Target cells can be either
Definition
a preysynaptic neuron
a postsynaptic neuron
Term
What do neurons do?
Definition
They generate and transmit signals called action potentials
Term
what is the membrane potential?
Definition
Difference in charge across the plasma membrane of a cell
Term
What alters the membrane potential?
Definition
1)pumping ions against a concentration gradient
2)ion channels let ions back into the cell
Term
what can generate an action potential?
Definition
sudden changes in sodium and potassium channels
Term
What is resting potential?
Definition
the membrane potential of a living cell at rest. The interior is negative with respect to the exterior
Term
What is depolarization?
Definition
A change in the resting potential of a cell in which the interior becomes less negative(or even positive) compared to the exterior
Term
Hyperpolarization
Definition
a change in the resting potential of a cell in which the interior becomes more negative compared to the exterior
Term
What does the threshold do?
Definition
it ensures there is an all or nothing response to nerve stimuli which ensures the max. value is always reached
Term
what is a self regenerating action potential?
Definition
local currents flow to adjacent regions of the plasma membrane, bringing those areas to threshold as well
Term
How do action potentials move?
Definition
They are directional, they travel down the entire length of the the axon
Term
What do Myelinated neurons do?
Definition
have gaps called nodes of Ranvier that can speed action potentials along an axon
ex:Saltatory conduction
Term
Chemical Synapse
Definition
axon releases neurotransmiters directly into the synapse when the action potential reaches it, and the post synaptic membrane responds
Term
Electrical synapse
Definition
the action potential spreads
directly from a presynaptic cell to a postsynaptic cell
Term
Even though electrical synapses are fast, why don't they integrate information well?
Definition
1)they contain numerous gap junctions through which the action potential travels
2)Signal is not unidirectional
3)very few are in vertebrate nervous system
Term
Why is turning off a neurotransmitter just as important as turning it on?
Definition
1)enzymes may destroy the neurotransmitter soon after its release into the synapse
2)alternatively, neurotransmitter may diffuse away from the synapse, or be taken up by nearby cells
Term
What do sensory receptors do?
Definition
converts physical and chemical stimuli into neural signals
Term
How do sensory receptors convert chemical & physical stimuli into neural signals?
Definition
1)Sensory receptor proteins receive a signal
2)Receptor protein opens or closes ion channels in the cell
- releases neurotransmitter or creates
an action potential
Term
What does sensation depend on?
Definition
which neurons receive action potentials from sensory cells. Cell receptors vary among cells, and only those with proper receptors will recognize the signal
Term
How do sensory cells adapt?
Definition
give gradually diminishing responses to repeated stimulation
Term
Chemoreceptors
Definition
receptor proteins that bind to various molecules
Term
Pheremones
Definition
chemical signals used to communicate with other individuals
Term
Olfaction
Definition
sense of smell
Term
Gustation
Definition
sense of taste
Term
What does olfaction depend on?
Definition
chemoreceptors on cells in the epithelial
tissue at the top of the nasal cavity
Term
Odorant
Definition
a molecule that activates an olfactory
receptor protein (usually very specific)
Term
Glomeruli
Definition
bulbs formed from clusters of axons
from neurons expressing the same receptor
proteins
Term
Taste buds
Definition
clusters of chemoreceptors
Term
Where are taste buds located in most terrestrial vertebrates?
Definition
in the mouth
-humans have aprox. 10,000
Term
Where do aquatic vertebrates have their taste buds?
Definition
in the skin
Term
what are the 5 main tastes humans can recieve
Definition
bitter, salty, sweet, sour, umami
Term
How does one taste subtle flavors in food?
Definition
using a combination of olfaction and gustation
Term
Mechanoreceptors
Definition
sensory receptors that respond to mechanical forces.
-Often involve neurons that are associated with hairs. Movement of the hair stimulates the neuron
Term
Merkel’s discs
Definition
mechanoreceptor in the skin: adapt slowly, and provide continuous information about things touching the skin
Term
Meissner’s corpuscles
Definition
Mechanoreceptor in the skin: adapt rapidly, and provide information about changes in things touching the skin
Term
Ruffini endings
Definition
Mechanoreceptor in the skin: adapt slowly, and provide information about low frequency vibrations
Term
Pacinian corpuscles
Definition
Mechanoreceptor in the skin: adapt rapidly, and provide information about high frequency vibrations
Term
Stretch receptors
Definition
modified muscle cells embedded in connective tissue in muscle and innervated by sensory neurons
Term
Golgi tendon organ
Definition
found in tendons and ligaments and provides information about the force generated by a contracting muscle
Term
How do mechanreceptors in auditory systems work?
Definition
use hair cells to convert pressure waves into receptor potentials.
-Auditory systems gather sound waves, direct them toward the sensory organ, and amplify their effect on the mechanoreceptors
Term
What is the middle ear?
Definition
Air filled cavity between the tympanum and the inner ear
Term
what is the middle ear connected to?
Definition
the throat via Eustachian tubes
Term
What does the middle ear do?
Definition
Equilibrates pressure in the middle ear with the pressure outside.
-Ossicles transmit vibrations of the tympanic membrane to the oval window of the inner ear (malleus, incus, and stapes)
Term
Vestibular system
Definition
inner ear canal that is responsible for maintaining balance
Term
Cochlea
Definition
a tapered and coiled, fluid filled chamber
composed of three parallel canals that is
responsible for hearing (located in the inner ear)
Term
Reissner’s membrane
Definition
In the inner ear: separates the vestibular
canal and middle canal
Term
Basilar membrane
Definition
located in the inner ear: separates middle canal from the tympanic canal
Term
Organ of Corti
Definition
located in the inner ear: is positioned on the basilar membrane and contains hair cells with cilia that convert pressure waves into action potentials
Term
What 2 categories does hearing loss fall into?
Definition
Conduction defenses
Nerve defenses
Term
Conduction deafness
Definition
caused by the loss of function of the tympanic membrane or ossicles in the middle ear
Term
Nerve deafness
Definition
caused by damage to the inner ear or auditory pathways
-often occurs from repeated exposure to loud sounds
Term
Why are hair cells sensitive to being bent?
Definition
bending in one direction causes depolarization
bending in the other direction causes hyperpolarization.
Can detect gravity and momentum.
Are evolutionarily conserved (e.g.,lateral line)
Term
What do light sensory systems rely on?
Definition
photoreceptor cells
Term
Rhodopsins
Definition
pigment molecules that absorb light photons and transduce neural signals
Term
Rod cells
Definition
light sensitive cells in the retina that are
responsible for black and white vision
Term
Cone cells
Definition
photoreceptor cells in the retina that are
responsible for color vision.
-three types absorb different wavelengths of light
Term
Eye cups
Definition
concentrated photoreceptor cells
Term
Compound eyes
Definition
eyes that consist of many optical units called ommatidia
Term
Image framing eyes
Definition
eyes that can form images of the visual world
Term
How did convergent evolution occur?
Definition
with image forming eyes evolving separately in vertebrates and mollusks
Term
Skeletal muscle
Definition
muscle involved in many voluntary and involuntary movements
Term
Cardiac muscle
Definition
responsible for contractions of the heart
Term
Smooth muscle
Definition
involuntary muscles responsible
for movement of many hollow internal organs
Term
What do muscle fibers consist of?
Definition
contractile proteins:
1)Actin:thin filaments
2)Myosin:thick filaments
Actin and myosin filaments slide past each other in a ratcheting motion when muscles contract
Term
Myofibrils
Definition
bundles of actin and myosin filaments
arranged in an orderly fashion
Term
Sarcomeres
Definition
repeating units of a myofibril that have
distinct banding patterns
Term
How does smooth muscle contract?
Definition
All cells contract simultaneously
Term
Peristalsis
Definition
simultaneous contraction of smooth
muscle to force food through the digestive tract (smooth muscle)
Term
what plays a important role in smooth muscle contraction?
Definition
Calcium
Term
How are muscle twitches measured?
Definition
by the tension or force generated when a
muscle contracts
Term
Small force
Definition
one motor neuron innervates only one or a few muscle fibers
Term
Large force
Definition
one motor neuron innervates an entire bundle of muscle fibers
Term
Tetanus
Definition
continuous activation of the contractile
machinery
Term
what are slow twitch fibers controlled by?
Definition
Red muscle: Cells contain the protein myoglobin, many mitochondria, and are surrounded by many blood vessels, resulting in high levels of oxygen metabolism.
-Maximum tension is low, so they are resistant to fatigue and good for long term aerobic work
Term
what controls fast twitch fibers?
Definition
White muscles: Cells contain few mitochondria, have little myoglobin, and are surrounded by few blood vessels. Maximum tension is high, but these fibers fatigue easily.
-Contraction can only be maintained for short bursts because these fibers cannot generate ATP as readily as slow twitch fibers
Term
A muscle has an optimal length for achieving what?
Definition
maximum force.
Term
Stretched muscle
Definition
no overlap between actin and
myosin filaments means no cross bridges form and no force is generated
Term
Fully contracted muscle
Definition
z-lines overlap so no force is generated because the muscle cannot get any shorter
Term
what does exercise do?
Definition
Increases muscle strength and endurance
Term
Strength
Definition
maximum force a muscle exerts
-strength training
Term
Endurance
Definition
work capacity or length of time a given workload can be sustained
-Aerobic exercise
Term
What is muscle performance limited by?
Definition
ATP supply
Term
Immediate system
Definition
uses preformed ATP and creatine phosphate
Term
Glycolytic system
Definition
metabolizes carbohydrates to lactate and pyruvate (i.e., fermentation)
Term
Oxidative system
Definition
metabolizes carbohydrates or fats all the way to H2O and CO2
Term
what is the skeletal system?
Definition
rigid support structure that muscles can contract against
Term
Hydrostatic skeleton
Definition
volume of fluid enclosed in a body cavity surrounded by muscle
Term
Exoskeleton
Definition
a hardened outer surface to which muscles can attach
Term
Endoskeleton
Definition
an internal skeleton to which muscles can attach and pull against
Term
Cartilage
Definition
stiff yet flexible connective tissue
Term
Bone
Definition
rigid component of vertebrate skeletal
systems that contains an extracellular matrix of insoluble calcium phosphate crystals and collagen
Term
Membraneous bone
Definition
forms on a scaffold of connective tissue membrane
Term
Cartilage bone
Definition
forms first as a cartilagenous structure
resembling the mature bone, then ossifies to become bone
Term
Compact bone structure
Definition
solid and hard
Term
Cancellous bone structure
Definition
rigid, but pores give it a spongy appearance
Term
Osteoblasts
Definition
a cell that lays down the protein matrix
of bone: formation
Term
Osteocytes
Definition
an osteoblast that has been enclosed in
lacunae (cavities) within the bone it has built: metabolism, nutrient/waste exchange
Term
Osteoclasts
Definition
a cell that dissolves bone: resorption &
degradation of existing bone
Term
when do bones and muscles work together?
Definition
around joints where two (or more) bones come together.
-Different joints allow motion in different directions
Term
How do muscles move joints?
Definition
they attach to them
Term
Flexor
Definition
the muscle that bends the joint
Term
Extensor
Definition
the muscle that extends the joint
Term
Ligaments
Definition
flexible bands of connective tissue that hold bones together at the joint
Term
Tendons
Definition
straps of connective tissue that attach muscles to bones
Term
How do bones act?
Definition
as levers that have an effort arm and a load arm working together around a fulcrum.Force depends on the ratio between effort and load arms.
-A high effort to load arm ratio yields great force
-A low effort to load arm ratio results in low force
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