Shared Flashcard Set

Details

BIOL2416 iGenetics CH 6 Translation Flashcards
iGenetics Exam 1 Flashcards
45
Biology
Undergraduate 2
10/02/2008

Additional Biology Flashcards

 


 

Cards

Term
 
 
 
 amino acid
Definition

 

 

 

protein building block

 

Term
 
 
 
 
peptide bond 
Definition
 
 
 
 
covalent bond between two amino acids 
Term

 

 

 

 

 

translation 

Definition

 

 

 

 

 

protein synthesis 

Term

 

 

 

 

 

translation catalyzed by? 

Definition

 

 

 

 

ribosomes 

Term

 

 

 

 

translation happens where? 

Definition

 

 

 

 

 

in cytosol 

Term

 

 

 

peptide bonding reaction is called?

Definition

 

 

 

dehydration synthesis, a.k.a. condensation

 

Term

 

 

translational start codon? 

Definition

 

 

 

AUG 

Term

 

 

 

Codon 

Definition

 

 

3 adjacent mRNA nucleotides with meaning

 

Term

 

 

 

sense codon 

Definition

 

 

 

codes for an amino acid 

Term

 

 

 

nonsense codon 

Definition

 

 

a.k.a. stop codon

 

codes for release factor - stops translation

 

UAA, UAG, UGA 

Term

 

 

 

start codon codes for?

Definition

 

 

 

  • methionine (met)
  • start of translation (beginning of gene)
Term

 

 

dehydration synthesis involves? 

Definition

 

 

  • removal of OH from first amino acid
  • removal of H from second amino acid
  • formation of OH+H=H2O water
  • formation of peptide bond between aa's 
Term

 

 

amino acid composed of? 

Definition

 

 

  1. central carbon
  2. H
  3. NH2 (amino group)
  4.  COOH (acid group)
  5. variable R group
Term

 

 

2 kinds of codons 

Definition

 

 

  • sense
  • nonsense 
Term

 

 

start codon 

Definition

 

 

 

AUG 

Term

 

 

AUG 

Definition

 

 

start codon 

Term

 

 

UAA 

Definition

 

 

 

stop codon 

Term

 

 

UAG 

Definition

 

 

stop codon 

Term

 

 

UGA 

Definition

 

 

 

stop codon 

Term

 

 

reading frame 

Definition

 

 

1 of 3 ways to read the same mRNA sequence 

Term

 

 

frameshift 

Definition

 

 

shift from one reading frame into another 

Term

 

 

frameshift mutation caused by? 

Definition

 

 

  • indels
  • involving other than 3n DNA bases 
Term

 

 

indel 

Definition

 

 

insertion/deletion at DNA level 

Term

 

 

polypeptide 

Definition

 

 

  • string of amino acids
  • can be whole protein or subunit of protein 
Term

 

 

1' level of protein folding 

Definition

 

 

 

amino acid sequence 

Term

 

 

2' level of protein folding 

Definition

 

 

 

  • Alpha Helix or Beta Pleated Sheet
  • regular folding of amino acid chain
  • by H-bonding 
Term

 

 

3' level of protein folding 

Definition

 

 

  • irregular folding
  • due to disulfide bridges, H-bonding, hydrophobic interactions, vd Waals attractions, ionic bonding
  • may result in whole protein 
Term

 

 

4' level of protein folding 

Definition

 

 

  • 2 or more subunits (polypeptides) getting together to form whole protein
  • subunits may be same or different 
Term

 

 

keyhole pockets in ribosomes 

Definition

 

 

 

E, P, and A 

Term

 

 

translocation 

Definition

 

 

ribosome hops over by one codon in mRNA 

Term

 

 

rbs stands for? 

Definition

 

 

  • ribosome-binding site
  • a.k.a Shine-Dalgarno site 
Term

 

 

Where does tranlation start? 

Definition

 

 

start codon AUG 

Term

 

 

triplet code means? 

Definition

 

 

each codon is 3 adjacent mRNA nucleotides 

Term

 

 

triplet code is unambiguous means? 

Definition

 

 

each codon always has the same meaning

 

it means what it says 

Term

 

 

triplet codon is degenerate means? 

Definition

 

 

there is more than one way to say the same thing

 

(there can be more than one codon coding for the same amino acid)

Term

 

 

translation - phases? 

Definition

 

 

  1. initiation
  2. elongation
  3. termination 
Term

 

 

mRNA stands for? 

Definition

 

 

messenger RNA 

Term

 

 

tRNA stands for? 

Definition

 

 

transfer RNA 

Term

 

 

anticodon 

Definition

 

 

unpaired loop in tRNA that is complementarty (matches) mRNA codon 

Term

 

 

job of tRNA? 

Definition

 

 

bring correct amino acid to ribosomes at correct time during translation 

Term

 

 

charged tRNA 

Definition

 

 

tRNA carrying the amino acid specified by its anticodon 

Term

 

 

release factor 

Definition

 

 

protein that binds to a stop codon to stop translation 

Term

 

 

SRP stands for? 

Definition

 

 

  • signal recognition particle
  • recognizes protein signal sequence to guide proteins into ER for eventual export 
Term

 

 

signal sequence 

Definition

 

 

molecular luggage tag that marks proteins for export or transport to other organelles 

Supporting users have an ad free experience!