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BIOL 3320
Blood Notes
33
Biology
Undergraduate 3
01/27/2013

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Term
Blood
Definition
liquid connective tissue, chief means of transport within the body
Term
Plasma
Definition
the liquid matrix found in blood vessels. composed of water & dissolved substances. (plasma proteins, electrolytes, nutrients, gases, regulatory substances, & waste products)
Term
Formed Elements
Definition
red & white blood cells and platelets
Term
Hemopoiesis
Definition
the process by which formed elements of blood develop
Term
Erythrocytes
Definition
red blood cells (RBC), bioconcave (no nucleus), contain hemoglobin which carries oxygen *most abundant cell in the body*
Term
Erythropoiesis
Definition
making red blood cells
Term
Thrombocytes
Definition
platelets, small cell fragments that facilitate & promote blood clotting (platelets)
Term
Leukocytes
Definition
white blood cells (WBC), have a nucleus, do not have hemoglobin, responsible for fighting infection
Term
Leukocytosis
Definition
increase of WBC's
Term
Leukopoeisis
Definition
making of WBC's
Term
Leukopenia
Definition
low or lack of WBC's
Term
Emigration
Definition
WBC's can leave the bloodstream to fight infections by squeezing through the cell layers of blood vessels
Term
Granular Leukocytes
Definition
have small granules in the cytoplasm (look like grains of sand)
Term
Neutrophil
Definition
nucleus has 2-5 lobes, which are connected by a thin chromatin filament, small grains, most abundant leukocyte, increase due to bacterial infection, burns, & stress
Term
Eosinophil
Definition
nucleus has 2 large lobes, which are connected by a thick strand, large grains, increase in number due to allergic reactions & parasitic infections (granules look pink)
Term
Basophil
Definition
nucleus has 2 lobes, but is obscured by many granules, the whole cell looks dark & grainy, cell is small, increases due to allergic reactions & cancers (granules look purple or blue)
Term
Agranular Leukocytes
Definition
no grains in the cytoplasm
Term
Lymphocyte
Definition
nucleus is large & round, taking up most of the cell, cell is large, increase with viral infections (AIDS attacks these)
Term
Monocytes
Definition
nucleus is "horseshoe" shaped or may look like the letter "M", cell is huge, increase in number due to viral & fungal infection, leukemia & chronic diseases. these cells migrate out of the bloodstream becoming macrophages that will gather at the site of infection
Term
Phagocytosis
Definition
process of cell eating, both monocytes & neutriphils engulf material for disposal
Term
Antigens
Definition
anything that is recognized as foreign & provokes an immune response, proteins located on the surface of red blood cells (generates immune response)
Term
Antibodies
Definition
bind to & react with specific antigens
Term
Rh Factor
Definition
an additional antigen found on the surface of RBC's
Term
Erythroblastosis fetalis
Definition
occurs when a mom is negative & babies are positive. Rh negative mother is exposed to Rh+ antigens from 1st baby. the 1st baby is unaffected. after he birth, mother develops antibodies against Rh. if the woman has a second Rh+ baby her antibodies will cross the placenta & attack
Term
Universal Recipient
Definition
can receive blood from any blood type donor, AB positive
Term
Universal Donor
Definition
can give blood to any other blood type, O negative
Term
Transfusion Reaction
Definition
occurs when & incompatible blood type is given. antibodies in the recipient blood react with donor antigens causing RBC's to stick together, clot, & rupture
Term
Hematocrit
Definition
measures the percent of blood that is RBC's, that is, it measures RBC volume (packed cell volume)
Term
Polycythemia
Definition
abnormal RBC count or volume, means that there are more cells than there should be
Term
Anemia
Definition
a condition in which the oxygen-carrying capacity of blood is reduced. characterized by reduced numbers of RBC's or a low amount of hemoglobin
Term
Hemocytometer
Definition
tells RBC count
Term
Hemoglobinometer
Definition
measures hemoglobin in blood
Term
ABO Blood Grouping
Definition
tells what blood type and Rh factor you are
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