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BIOL 145 Exam 1
Exam 1
118
Biology
Undergraduate 3
09/03/2014

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Term
organs of the cardiovascular system
Definition
heart
blood
blood vessels
Term
function of cardiovascular system
Definition
transports nutrients, gasses, waste, and hormones throughout the body
Term
heart
Definition
right side pumps to lungs (lower pressure)
left side pumps to body (higher pressure)
regulated by hormones and control from the Vagus nerve
Term
blood
Definition
45% RBC
55% Plasma
Term
plasma made up of...
Definition
white blood cells
proteins
platelets
water, ions, nutrients, and waste
Term
vessels
Definition
arteries (high pressure)
capillaries (leaky)
veins (low pressure)
Term
organs of the digestive system
Definition
liver
stomach
pancreas (exo)
small intestine
large intestine
Term
function of the digestive system
Definition
breaks down food and absorbs nutrients
Term
bile
Definition
organic salt that dissolves fat
Term
pancreas (exo)
Definition
releases a strong base and enzyme that only work in a basic solution
Term
how does the digestive system absorb food?
Definition
small int. absorbs nutrients and most water
lg. int. absorbs remaining water
portal vein drains all of the gut organs
liver processes all of the nutrients and cleans the blood of bacteria
Term
glucose
Definition
processed in the liver
Term
glycogen
Definition
stored temporarily in the liver
Term
gluconeogenesis
Definition
the creation of new glucose from fat and protein
Term
digestive nervous system
Definition
operates independently of the CNS
controls smooth muscle movement to facilitate digestion
Term
organs of the urinary system
Definition
kidneys
bladder
Term
function of the urinary system
Definition
filters urea and toxins from the blood
maintains the salt and water balance of the blood
Term
nephrons
Definition
small holes in the capillaries to help filter blood vessels
Term
organs of the respiratory system
Definition
trachea
lungs
Term
function of the respiratory system
Definition
allows blood to exchange CO2 and O2 with the air
Term
bronchi
Definition
air tubes which continue to split apart to supply all parts of the lung with fresh air in each breath
terminate at alveoli
Term
alveoli
Definition
balloon-like structures in the cells that expand and shrink with each breath
Term
organs of the endocrine system
Definition
thryoid
parathyroid
pancreas (endo)
kidneys
adrenals
ovaries/testes
Term
function of the endocrine system
Definition
maintains healthy levels of the blood by controlling all of the organs with control molecules
Term
function of the thyroid
Definition
controls metabolic rate of the body with thyroxine
Term
function of adrenals
Definition
releases adrenaline, which causes body-wide fight or flight response
Term
function of the ovaries
Definition
release estrogen and progesterone, controlling the menstrual cycle
Term
function of the testes
Definition
release testosterone, which causes masculinization of a human
Term
organs of the lymphatic system
Definition
lymph
lymph nodes
lymphatic vessels
Term
function of the lymphatic system
Definition
drains back to the blood
filters extravascular fluid for debris
provides a route for immune cells to get back to the blood
Term
lymphatic vessels
Definition
absorb fluid that is pushed out of the capillaries
Term
lymph nodes
Definition
densely packed with immune cells
activated once an immune cell encounters a threat in the extravascular space
Term
spleen
Definition
similar to lymph node dedicated to the blood rather than lymph cleans the blood from infections
Term
organs of the reproductive system (male and female)
Definition
female: mammary glands, ovaries, fallopian tubes, uterus, vagina
male: testes, penis
Term
function of the reproductive system
Definition
to produce egg and sperm cells (gametes)
to transport and sustain gametes
to nurture developing offspring
to produce hormones
Term
eggs
Definition
released from the ovaries into the fallopian tubes finite number of eggs
Term
sperm
Definition
constant production
haploid (only contain half of the necessary chromosomes)
Term
receptor
Definition
proteins that transmit signals in the cell, and that can result in an effect on the body
Term
types of cardiovascular diseases
Definition
arrhythmia
heart valve disease
endocarditis
heart pump failure
Term
how is sugar regulated by the body?
Definition

pancreas produces and secretes insulin to lower blood sugar levelsĀ 

pancreas produces and secretes glucagon to raise bood sugar levelsĀ 

the liver is the main storage site for sugar (glucose)

Term
diabetes
Definition
the inability of the body to regulate its blood sugar levels
Type 1: juvenile onset
Type 2: adult onset
Term
diabetes treatment
Definition
diet and exercise
blood sugar monitoring
insulin administration (injections or pump)
Term
arrhythmia
Definition
irregular heart rate or rhythm caused by delayed or blocked electrical signal
Term
types of arrhythmia
Definition
atrial fibrillation (Afib)
bradycardia
tachycardia
Term
arrhythmia treatments
Definition
anti-arrhythmics
anti-coagulants
cardioversion
pacemaker
Term
anti-arrhythmics
Definition
stabilizes/slows down electrical signaling and suppress abnormal rhythms
Term
anti-coagulants
Definition
blood thinners
prevent clotting, which can obstruct blood flow and worse arrhythmias
reduces risk of heart attack/stroke
risk of excessive bleeding and improper wound healing
Term
cardioversion
Definition
low energy shocks trigger a normal heart rhythm
outpatient procedure
Term
pacemakers
Definition
monitors hear rate and sends electrical signals
Term
receptor
Definition
proteins that transmit signals in the cell, and that can result in an effect on the body
Term
types of heart valve disease
Definition
regurgitation (valve doesn't close all the way)
stenosis (valve doesn't open all the way)
Term
heart valve treatments
Definition
vasodilators
anti-arrhythmics
valve repair surgery
valve replacement surgery
Term
endocarditis
Definition
bacterial or fungal infection of the heart valve
common among drug users
Term
heart failure
Definition
heart is weakened and cannot pump enough blood to meet the body's needs
chronic disease requiring lifelong management
Term
causes of heart failure
Definition
heart attack
high blood pressure
enlarged heart
Term
symptoms of heart failure
Definition
shortness of breath
swelling in legs, ankles, and feet
rapid/irregular heart beat
chest pain
Term
heart failure treatments
Definition
beta blockers
ACE inhibitors
diuretics
vasoldilators
Term
arteries
Definition
carry oxygenated blood away from the heart to the body
Term
veins
Definition
carry deoxygenated blood back into the heart
Term
capillaries
Definition
major site of gas exchange
Term
types of vascular disease
Definition
atherosclerosis
coronary heart disease
Term
coronary heart disease
Definition
buildup of plaque in arteries supplying blood to the heart muscle
over time, weakens heart muscle, resulting in heart failure
Term
atherosclerosis
Definition
disease of the arteries in which fatty lesions develop on inside surface of arterial walls
Term
vascular disease treatment
Definition
cholesterol-modifying medications anti-coagulants angioplasty (surgery-balloon) stent (surgery-wire) bypass surgery
Term
heart pump failure treatments
Definition
beta blockers
ACE inhibitors
diuretics
vasodilators
Term
how are nutrients and oxygen absorbed into the blood?
Definition
nutrients are absorbed into the blood from the gut in the small intestine oxygen is absorbed into the blood in the lungs
Term
where are CO2 and NH3 released in the blood?
Definition
lungs release CO2, because it is a gas
ammonia is converted to urea, and urea is released from the blood into the urine in the kidneys
Term
where are RBCs made and broken down?
Definition
made in the bone marrow
broken down (after 4 months) in the spleen
Term
describe the path nutrients take when you swallow coffee.
Definition
stomach
small intestine
absorbed into the blood
passes through blood vessels
liver
right side of heart
lungs
left side of heart
kidneys, filtered into urine
ureter
bladder
Term
thryoxine
Definition
released by thryoid, controls metabolic rate
Term
adrenaline
Definition
released by adrenals, controls fight-or-flight response
Term
estrogen and progesterone
Definition
released by ovaries, controls menstrual cycles and release of eggs
Term
testosterone
Definition
released by testes, controls masculinization
Term
insulin
Definition
released by pancreas, controls storage of glucose
Term
glucagon
Definition
released by pancreas, controls creation of glucose
Term
parathyroid hormone (PTH)
Definition
released by parathyroid, controls levels of calcium
Term
erythropoetin
Definition
released by kidneys, controls production of new RBCs
Term
pharmocology
Definition
the study of how drugs act on the body
Term
drug
Definition
a substance other than food that has an affect on the body
Term
types of drugs
Definition
man-made
natural
endogenous (within the body)
Term
therapeutic index
Definition
difference between the amount of a drug it takes to elicit a response and the amount it can be harmful
Term
half life of drugs
Definition
how long it takes for a drug to lose half of its effectiveness
Term
efficacy
Definition
maximum effect, no matter the dose
Term
potency
Definition
amount of a drug it takes to produce a given effect
Term
method of action
Definition
MOA
the way in which a drug produces a physiological effect through its binding to a receptor
Term
ligand
Definition
an endogenous molecule or exogenous drug that binds to a specific receptor
Term
receptor
Definition
a protein that transmits signals in the cell and can result in an effect in the body
Term
enzyme
Definition
a molecule that causes biological change
Term
agonist
Definition
a drug that mimics a ligand and can cause the same response
Term
antagonist
Definition
a drug that binds to a receptor and blocks a ligand
Term
endogenous
Definition
within the body
Term
exogenous
Definition
outside of the body
Term
metabolize
Definition
break down
liver enzymes are responsible for metabolism of drugs
Term
ion channel receptors
Definition
fast acting
open to let ions in or out
Term
GPCR
Definition
G-protein coupled receptor
slower acting
signal transduction cascade (domino effect)
Term
enzyme-linked receptors
Definition
ligand binding causes enzymatic reaction in the cell
causes signal transduction cascade
Term
how do drugs, receptors, and cell types give us a variety of effects?
Definition
2 drugs 1 receptor
1 drug, 2 receptors
2 drugs, 2 receptors
Term
how do side effects occur?
Definition
too much of a drug
off-target sites (i.e. two dif receptors)
ineractions (i.e. tylenol and alcohol)
Term
metabolism of drugs
Definition
broken down in the liver
Term
ways to take drugs
Definition
orally
nasally
intravenously
inhalation
Term
allergies
Definition
immune reaction caused by a normally harmless environmental antigens
Term
allergens
Definition
any foreign substance that can cause an allergic reaction
common allergens: rye grass, ragweed, penicillin, nuts, seafood, eggs, milk, bee venom, wasp venom, dust mites, mold spores, animal hair/dander, latex
Term
symptoms of asthma attack
Definition
coughing
tight chest
wheezing
shortness of breath
blue tinge to skin/nails
Term
local allergies
Definition
allergic response that occurs at the point or area of contact
seasonal allergies, asthma, eczema, food allergies
Term
systemic allergies
Definition
quick and sever whole-body reaction to a substance (anaphylaxis)
Term
treatments for local allergies
Definition
antihistamines
decongestants
NSAIDS (non-steroidal anti-inflammatory drugs)
steroidal anti-inflammatory
nasal corticosteroids
mast cell stabilizers
leukotriene modifiers
Term
asthma
Definition
chronic disease caused by either genetic or environmental factors
Term
cause of asthma
Definition
genetic
environmental (exposure to air pollutants, viral respiratory infections)
Term
characteristics of asthma attack
Definition
constriction
inflammation
obstruction
Term
hygiene hypothesis
Definition
lack of early childhood exposure prevents the immune system from developing the ability to distinguish between innocuous and harmful antigens
Term
mast cells
Definition
found just below the skin and store granules of histamines which are released upon activation by allergen
Term
histamine
Definition
protein stored in mast cells
causes blood vessels to dilate and smooth muscles to contract
Term
leukotrienes
Definition
mediate inflammation
triggers contraction of smooth muscles
Term
types of asthmatic attacks
Definition
allergic asthma
intrinsic asthma (exercise or cold temperatures)
Term
treatments of asthma
Definition
lifestyle (exercise)
medication (fast-acting or long-term)
Term
systemic reaction treatment
Definition
epinephrine (epipen)
Term
fast-acting asthma treatment
Definition
use within 30 min of asthma attack
drugs
Term
long-term asthma treatments
Definition
nasal corticosteroids
mast cell stabilizers
leukotriene modifiers
hyposensitization therapy (allergy shots)
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