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Biochemistry
Dr. Shaw Q1
15
Chemistry
Graduate
04/12/2010

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Term
Telomere
Definition
region of repetitive DNA at the end of a chromosome which protects the end of the chromosome from deterioration.
Term
What are minisatellites used for and how long are the base pairs?
Definition
Used for DNA fingerprinting and from 12-100 bp long
Term
What is the spliceosome?
Definition
The molecular machine that removes introns and joins exons.
The primary transcript joins with snRNPs to form a spliceosome
Term
Is transposition good or bad?
Definition
Can be both.
If occurs in Somatic cancel can result in Cancer. Can cause gene replication.
However, it stirs the genetic pot and contributes to variability.

Can be thought of parasites that simply replicate themselves
Term
What are the 3 types of RNA that participate in the process of Protein Synthesis
Definition
mRNA, tRNA, rRNA
Term
What are the base pair pairings?
Definition
Adenine with Thymine and Cytosine with Guanin. In RNA, Thymine is replaced with Uracil
Term
What does mRNA do?
Definition
Carries genetic information from the nuclear DNA to the cytosol where it is used as a template for protein synthesis
Term
The process of RNA synthesis is called?
Definition
Transcription
Term
What does tRNA do?
Definition
It serves as an "adaptor" molecule that carries a specific AA to the site of protein synthesis
Term
snRPs
Definition
Small Nuclear Ribosomal Proteins. They mediate the process of splicing
Term
DNA Directed RNA Synthesis consists of (4 steps)
Definition
Initiation, Elongation, Termination, Postransciptional modification
Term
What is a system that can be turned off by biochemical cue called?
Definition
Repressible
Term
DNA is?
Definition
De-oxy ribonucleic acid. Double stranded helix with antiparallel strands and bases linked by hydrogen bonds.
Term
Amino-acyl tRNA
Definition
Activating enzymes that attach specific AA's to tRNA forming "charge tRNA"
Term
Point Mutations vs. Chromosomal Mutations
Definition
Point: Silent, missense, nonsense, frame-shift)
Chromosomal: deletions, duplications, inversions, translocations)
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