Term
|
Definition
| Adverse drug reactions which are linked to genetic variations btwn individuals known as polymorphins |
|
|
Term
1) What are SNPs?
2) What are they used to create?
3) Where are SNPs frequently found? |
|
Definition
1) each allele of a gene is ass w/certain markers called SNPs that occur in,around the gene of interest
2) patterns of SNPs are used to create a halpotype, that indicate that a disease-causing allele is present
3) SNPs most frequently in surround, non-coding DNA
3) |
|
|
Term
| SNPs are used as what for alleles? |
|
Definition
| SNPs are used as markers to det. which allele of given gene an individual carries |
|
|
Term
| Can SNPs be found within the coding region? If so what happens? |
|
Definition
| Yes SNPs can be found within coding regions causing a change in coding sequence |
|
|
Term
| What does it mean for SNPs to have extremely tight association btwn given allele and the SNPs surrounding it? |
|
Definition
| if a SNP is associated w/given allele, there is an extremely high probability that the presence of the SNP indicates the presence of that allele |
|
|
Term
| 90% of genome variation is in form of what? |
|
Definition
| they are in the form of SNPs- single nucleotide polymorphisms |
|
|
