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Biochemistry Ch. 5 - Lipid Structure and Function
MCAT
13
Biochemistry
Undergraduate 3
06/07/2016

Additional Biochemistry Flashcards

 


 

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Term
phospholipids
Definition
fats that contain a phosphate and alcohol that comprise the polar head group, joined to a hydrophobic fatty acid tail by phosphodiester linkages
Term
glycerophospholipids
Definition
  • phospholipids with a glycerol backbone bonded by ester linkages to two fatty acids and by a phosphodiester linkage to a highly polar head group
  • they are named by their head group

[image]

x denotes the head group 

Term
sphingolipids
Definition
  • sphingosine backbone; long-chain, nonpolar fatty acid tails and polar head groups
  • 4 kinds: ceramide, sphingomyelins, cerebrosides and gangliosides
Term
sphingosine
Definition

[image]

the backbone of sphingolipids; the fatty acid will attach at the amine group and the head group will attach a the terminal hydroxyl group

Term
ceramide
Definition
[image]
Term
sphingomyelin
Definition
  • either have phosphatidylcholine or phosphatidylethnolamine for head group

[image]

phosphatidylcholine

 

remove the 3 carbons attached to the amine group in the choline and you have phosphatidylethnolamine

 

Term
glycosphingolipids
Definition
  • attached to sugar moieties instead of phosphate group
  • found mainly on outer surface of plasma membrane
  • further classified into cerebrosides or globosides

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cerebrosides have a single sugar

[image]

globosides have two or more

 

Term
terpenes
Definition
  • odiferous steroid precursors made form isoprene
  • one terpene (monoterpene) contains two isoprenes

[image]

isoprene

 

 

Term
steroids
Definition
  • contain three cyclohexane rings and oen cyclopentane ring with functional groups determining the specific steroid

[image]

Term
cholesterol
Definition
[image]
Term
prostaglandins
Definition
autocrine and paracrine signaling molecules that regulate cAMP levels; they have powerful effects on smooth muscle contraction, body temperature, the sleep-wake cycle, fever, and pain
Term
What are the fat soluble vitamins and what are their functions?
Definition
  • vitamin A (carotene) - metabolized to retinal for vision and retinoic acid for gene expression in epithelial development
  • vitamin D (cholecalciferol) - metabolized to calcitriol in the kidneys and regulates calcium and phosphorus homeostasis in the intestines (increasing calcium and phosphate absorption), promoting bone formation
  • vitmain E (tocopherols) - act as biological antioxidants; their aromatic rings destroy free radicals
  • vitamin K (phylloquinone and menaquinones) - important for formation of prothrombin, a clotting factor; performs posttranslational modifications on a number of proteins, creating calcium-binding sites
Term
Why are triacylglycerols the preferred way to store energy?
Definition
  • one glycerol contains three fatty acids
  • carbon atoms in lipids are more reduced than carbohydrates meaning they will give more energy
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