Term
| What enzyme is a control point of catabolic flux? |
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Definition
| Pyruvate Dehydrogenase Complex (Pyruvate DH) |
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Term
| The Coenzyme Q Redox center acts as... |
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Definition
| A gateway between two electron and one electron acceptors |
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Term
| what compound inhibits the synthesis of ATP from oxidative phosphorylation by blocking electron flow at complex III? |
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Definition
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Term
| The Malate-Aspartate shuttle allows |
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Definition
transfer of oxaloacetate (as aspartate) across the membrane transfer of NADH across the inner membrane Transfer of reducing equivalents across the membrane replenishment of oxaloacetate. |
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Term
| The enzymes that catalyze a reaction that directly replenishes oxaloacetate are... |
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Definition
Malate Dehydrogenase (Malate DH) Pyruvate Carboxylase Pyruvate Dehydrogenase |
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Term
| The pentose phosphate pathway generates ___ for use in anabolic reactions and occurs when there's a large excess of ___ |
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Definition
|
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Term
| Cytochrome P450 _____ with drug activity, ____ compounds, both _____ enzyme activity and ____ solubility |
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Definition
| Hydroxylating altering increasing |
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Term
| deficincy of pyruvate carboxylase would ___ gluconeogenesis |
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Definition
|
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Term
| Acetyl-CoA combines with ___ to form citrate |
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Definition
|
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Term
| An animal with the UCP-1 protein would... |
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Definition
| Generate excess heat and have lower energy levels |
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Term
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Definition
| an antibacterial that inhibits fatty acid biosynthesis |
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Term
| Starting metabolites for faty biosynthesis are activated by ___ |
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Definition
|
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Term
| lipoproteins formed in the intestinal mucosal cells are called... |
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Definition
|
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Term
| ___has 6 active sites that catalyze different reactions in FA biosynthesis |
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Definition
| Eukaryotic fatty acid synthase |
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Term
| Malonyl CoA ACP transacyclase is not found in.... |
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Definition
|
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Term
| CoA dehydrogenase is found... |
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Definition
|
|
Term
| beta-oxidation of fatty acids is inhibited by... |
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Definition
|
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Term
| Patients with CPT II deficiency... |
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Definition
| do not make enough acetyl CoA |
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Term
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Definition
|
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Term
| ALA synthase is inhibited by... |
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Definition
|
|
Term
| thymidylate synthase is inhibited by |
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Definition
|
|
Term
| inhibition of HMG CoA reductase would result in... |
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Definition
| increased uptake of LDL particles by cells |
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Term
| Thymidylate synthase is important in... |
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Definition
| DNA synthesis and as a target in cancer therapy |
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Term
| Initiation of DNA Replication requires... |
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Definition
| mechanism that binds initiation proteins, and generates a Tus Binding |
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Term
| RNA polymerase subunit A is responsible for... |
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Definition
| initiation, interaction with regulatory proteins, and acts as a promoter |
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Term
| RNA polymerase B is responsible for |
|
Definition
| initiation and enlongation |
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Term
| RNA polymerase subunit B' is used for |
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Definition
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