Term
| lipophilic cell surface receptor |
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Definition
Fever/pain/adrenaline
fast response
FAP |
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Term
| Hydrophilic that interact with cell surface receptor |
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Definition
Don't cross membrane. Large. Peptide
Glucagon, insulin, GH
PIGG |
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Term
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Definition
Diffuse. Steroids. adreocortical. gonad. thyroid.
TGADS |
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Term
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Definition
| Ligand binds receptor. Activates GTP. Alpha subunit disocaites BY. Alpha activates adenyl cyclase. This activates kinases / camp. |
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Term
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Definition
| Ligand binds receptor. Activates GTP. Alpha subunit disocaites BY. Alpha activates adenyl cyclase. This activates kinases / camp. |
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Term
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Definition
Ligand binding changes conformation allowing ion flow.
eX: neural transmitters. (acetycholine) |
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Term
| Tyrosine Kinase Binding Receptor. |
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Definition
| Hormones bind 2 external receptor. THis activates auto-phosphorylation. This pi activates other messengers and this process cascades down. CH2->RAS(gtp)->RAF->MAPK->transcription |
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Term
| Receptors with intrinsic enzymatic activity |
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Definition
Insulin induced tyrosine. phosphatases.
1 receptor with many functions. Cascades |
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Term
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Definition
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Term
| Two types of protein kinase |
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Definition
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Term
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Definition
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Term
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Definition
Deactivates Adenylate cyclase - no cAMP. inhibitory
Activates creates tons of cAMP. Stimulates |
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Term
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Definition
Try
These are docking sites |
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Term
PTB SH2 bind PH.
PTB binds N terminal. (TRK n terminal is extracellular)
SH2 BIND c terminal. |
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Definition
| N terminal has targeting region |
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Term
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Definition
Fasl TNF
Stress / inflamation |
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