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| Something hydrophobic and insoluble in water. |
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| Components of fats, oils, and membrane components. Long chain carboxylic acid. |
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| No C-C double Bonds. Higher melting point than unsat. and increasing mp with chain length |
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| DOUBLE BONDS. Lower melting point than sat. and increasing mp with chain length. |
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| Glycerol esterified to a fatty acid ( up to 3 fatty acids). Function to store energy long term. (mono, di, triglycerides |
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| Major cell membrane component. Glycerol+ two fatty acids and a polar x group. Phosphate is on C3. |
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| Contain alcohol backbone called sphingosine. Found in nerve cell membranes (myelin sheaths). NH3 group for fatty acid, and OH group for phosphate or sugar. |
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| Have fused ring system in common. Cholesterol is most common |
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| Protein type - cortisol - regulate metabolism and inflammatory response. |
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| Protein Type - Aldosterone - Kidney fxn |
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| Protein Type - estragen - sexual development fxn |
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Definition
Usually a cofactor or coenzyme for enzyme fxn.
Vit D -Regulate Calcium
Vitamin A - beta karotene
Vitamin K - Blood Clot
Vitamin E - Anit oxidant |
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| Peripheral Membrane Protein |
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Definition
| On the outside of the membrane. Associates with the surface. Polar Hydrophobic surface (charged). |
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| In the middle of the bilayer. If it crosses out of both ends then "transmembrane". Need hydrophobic surfaces to interact with interior. |
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| Peripheral proteins covalently linked to a lipid in order to anchor them on a membrane surface. 3 Types: Prenylated, FA acylated, s linked. |
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| Allow diffusion of ions across a membrane. These are frequently anti-biotic since membrane potentials are affected by ions. |
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| Bind and ion on one side of the membrane then diffuse to the other side to relocate the ion. |
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| Create a channel through which ions can flow across membrane |
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| Beta Barrel proteins the create a pathway for molecules to selectively cross a membrane. Selective by pore size and molecules that line pore. (if selective for cations then pore will be lined with anions (Glu, Asp) |
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| transports maltodrxtrins. Maltodextrine is helical, and is selected for w/ complementary shape. (Greasy Slide) |
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| a porin specific for water transport needed for rapid transport. (NOT HYDRONIUM b/c gate is composed of hydrogen bonding partners.) |
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| transporters that undergo a conformational change when ligand binds. Change allows passive transport to other side. |
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| Need gates so as to conserve energy. Active pumps would not be able to keep up with influx of ions. |
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| Mechano-Sensitive Ion Gate |
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Definition
| respond to local deformation of lipid bilayer. |
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| open/close based upon binding of extracellular messanger |
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| Open/Close based upon intracellular signal |
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| Open/ Close in response to membrane potential. |
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| Lose H, transfer of electron from one molecule to another. |
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| Transfer of a functional group from one molecule to another. |
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| Combine two molecules together. Usually requires ATP |
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| Elimination then addition. Break bonds in order to form new ones. |
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| Transition between isomers of the same molecule |
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