Term
| ___ ______ facilitate exchange of signals and small molecules between adjacent cells. |
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Definition
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Term
| Protein receptors are often |
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Definition
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Term
| Receptors coordinate with other proteins to amplify the signal(steps) |
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Definition
1. Hormone binding to receptor stimulates an inactive G protein. It exchanges GDP for GTP
2. G protein/GTP complex dissociates from receptor and activate adenylate cyclase to produce CAMP
3. G protein catalyzes hydrolysis of its bound GTP
4. G protein dissociates from adenylate cyclase, deactivating it |
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Term
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Definition
| decreases the rate of GTP to GDP |
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Term
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Definition
One of >30 bitter taste receptors in humans
Binds to molecules called glucosinolates
There is a prevalent set of 3 single nucleotide polymorphisms that affect activity
A49P, V262A, and I296V
AVI = nontaster while PAV = taster |
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Term
| G protein pathways are directly involved in or linked to three of the five basic senses |
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Definition
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Term
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Definition
| Stimulation of second messengers leads to release of neurotransmitters and stimulation of adjacent nerve cells like in the taste receptors. |
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Term
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Definition
1. Light stimulation of rhodopsin leads activation of a g-protein, transduction
2. Activated G-protein activates cGMP PDE
3. PDE hydrolyzes cGMP, reducing concentration
4.Leads to closure of Na channels |
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Term
| Proteins that binds molecules |
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Definition
Hemoglobin
Receptors
Channels
Actin
Gβ/γ |
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Term
| Proteins that do chemistry |
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Definition
Myosin
Gα
Polymerase
Trans-retinal regeneration proteins |
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