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aldotriose aldotetroses aldopentoses aldohexoses |
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| chiral carbon furthest from the aldehyde/ketone |
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| If –OH is on the right in Fisher projection, then is |
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| If -OH is on the left, then |
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These structures are stable in carbohydrates and are the results of linear to cyclic interconversion of sugars |
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In enzyme inhibitors aldehyde-alcohol products often will collapse back into the reactants at slow rate Sometimes a called “slow, tight binding” inhibitors |
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sugar to another group at anomeric carbon |
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| structural polysaccharide found in plants |
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| is a structural polysaccharide found in insects, fungi, and crusteceans |
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| is a storage polysaccharide |
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| multi-functional molecules |
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-glycosaminoglycan -involved in blood clotting |
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| Heparin enhances the activity of |
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| activated partial thromboplastin time |
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Clotting time Values of approximately 25 to 35 are considered “normal” |
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| the contact activation pathway |
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| Factor XIIa is activated by |
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negatively charged surfaces and high-molecular-weight kininogen Leads to activation of Factors VII, XI, and prekallikrein |
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blood vessel dilation immune system |
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| which can produce a local inflammation response |
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Over Sulfated Chondroitin Sulfate -> Activation of Kallikrein -> Release of C5a and C3a |
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Over Sulfated Chondroitin Sulfate -> Activation of Kallikrein -> Bradykinin release |
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| Glycosylation patterns are recognized by various |
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| Carbon hydrogen chain with a COO-/COOH at one end |
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| Backbone of a lipid-glycerol |
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3 carbon backbone
Can connect to up to 3 fatty acids
Sometimes have other groups (See a later slide) |
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| 3 properties of Steroids and Cholesterol |
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Amphipathic or hydrophobic 4 fused rings Structural and signaling molecules |
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| caused by vitamin D deficiency including lack of sunlight. Symptoms include bone weakness and deformities. |
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| involved in pain and fever in humans |
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| ______ Diffusion is common in bilayers |
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| carbohydrates, lipids and proteins |
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| Proteins can be modified to associate with |
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| Hydropathy plots can predict |
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| whether a protein has a transmembrane segment |
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| For TM region need to meet 2 requirements |
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High +ΔG
Long enough segment to span cell membrane (~15 to 20 AAs) |
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