Term
| After glucagon binds to GPCR (flow) |
|
Definition
| G-protein -> Adenylate Cyclase -> cAMP -> PKA -> glycogen breakdown -> free glucose |
|
|
Term
| After insulin binds to RTK (flow) |
|
Definition
| PI-3K -> PIP3 -> PKB -> inactivate AS160 -> Glut 4 goes to PM -> glucose receptors on PM |
|
|
Term
| After Ligand binds to GPCR Adenyl (flow) |
|
Definition
| Adenylate cyclase -> cAMP -> PKA |
|
|
Term
| After ligand binds to GPCR PLCbeta (flow) |
|
Definition
IP3 -> IP3receptor on smooth er -> Ca++ release -> Ca-Calmodulin -> where ever or PKC
DAG <-> PKC |
|
|
Term
| RTK after GAP phosphorylates (flow) |
|
Definition
| GAP -> inactivate signal pathway |
|
|
Term
| RTK Phosphoryl to PI-3K (flow) |
|
Definition
|
|
Term
|
Definition
(needs adaptor) -> RAS-GTP -> MAPKKK -> MAPKK -> MAPK
(kinase cascade) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Kinetochore
Polar (overlapping)
Astral |
|
|
Term
|
Definition
|
|
Term
|
Definition
contains centrioles
9 triplets of MTs |
|
|
Term
|
Definition
| 2 heavy chains + variety of intermediate/light chains |
|
|
Term
|
Definition
|
|
Term
|
Definition
Structure + Support (MT, MF, IF)
Intracellular transport (MT)
Contractility/ Motility (MT, MF)
Spatial organization (MT) |
|
|
Term
| What can a kinase cascade do? (MAPKKK -> MAPKK -> MAPK) |
|
Definition
Phosphorylate enzymes (post translational)
Phosphorylate transcription factors -> activate gene transcription (Transcription regulation) |
|
|
Term
| When does a pancriatic cell secret insulin? |
|
Definition
| When it recieves a calcium influx from IP3 |
|
|
Term
| Insulin receptors located where? |
|
Definition
|
|
Term
| How and why to activate glucose synthesis |
|
Definition
You need to inactivate GSK-3 by phosphorylating it
and you do this when glucose levels are too high |
|
|
Term
| Adaptor that connects SOS to RTK |
|
Definition
|
|
Term
|
Definition
Promote assembly/disassembly oof MT
microtubule association protein sinep |
|
|
Term
|
Definition
| PKB phosphorylates and stops transcription for it |
|
|
Term
| Where is gamma tubulin found? |
|
Definition
|
|
Term
|
Definition
9 MT doublets
2 Central pairs
9+2 array |
|
|
Term
|
Definition
|
|
