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BIO201 Nervous Sysyem
covering cns, pns, functions and structure
86
Physiology
Undergraduate 2
06/27/2011

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Term
What are the 2 main catagories in the nervous system?
Definition
Central Nervous system (CNS)
Peripheal Nervous system (PNS)
Term
Which nervous system are the brain and spinal cord associated with?
Definition
CNS
Term
What are the 2 sybcatagories of the PNS?
Definition
Somatic (SNS) and Automic (ANS)
Term
What are the 2 sub-catagories of the (ANS) Autonomic Nervous System?
Definition
Parasympathetic and Sympathetic
Term
Name the 3 main functions of the Nervous System (Hint - SMI)
Definition
SENSORY
MOTOR
INTEGRATION
Term
What does the sensory function do?
Definition
Monitors external and internal environments
Term
What does the Motor function do?
Definition
Regulates repsonse of body systems/ maintains homeostasis
Term
What does the Integration system do?
Definition
Integrates Info - higher brain function, memory, learning, intincts, IQ -personality, etc
Term
What is a NEURON?
Definition
Basic structure & functional unit of the nervous system
Term
Do NEURONS of the nervous system undergo mitosis?
Definition
Nope - too specialized
Term
What does the cell body contain?
Definition
neucleus and cytoplasm
Term
CELL BODY -
what is the rough ER called that gives color to the cell?
Definition
Nissl Bodies
Term
CELL BODY
What are groups of cell bodies called in the PNS?
In the CNS?
Definition
PNS - Ganglia
CNS - Nuclei
Term
CELL BODY
What make a cell appear more gray (gray matter)?
Definition
High numbers of cell bodies
Term
NUERONS:
Contain 3 main sections - Name them.
Definition
Cell Body
Dendrites
Axons
Term
Nuerons:
What are the short branched looking ends that bring info INTO the cell?
Definition
Dendrites.
Branched to create more surface area
Term
NEURONS:
What is the area of a cell that takes info FROM the neuron?
Definition
Axon
Term
What is the axon hillock?
What is another name for it?
Definition
It's the tapered region of a cell that exits the body.
AKA - The trigger zone
Term
NEURON:
What is the area of an axon that branches off to the side to head to another location?
Definition
Axon Collareral
Term
What are the little branches at the end of an axon called?
AKA?
Definition
Axon Terminals
AKA - Telodendria
Term
What is the enlarged end of an axon terminal that has the vesicles w/ nuerotransmitters inside?
Definition
Synaptic end bulbs
Term
Where can synaptic end bulbs be found?
Definition
At the end of Axon Terminals
Term
Why are some areas white (matter) vs. gray?
Definition
The white matter contains the bundles of myelinated axons. (Gray is more nissl bodies in the body of the cell...)
Term
What is a group of axons in the CNS called?
Definition
TRACKS
Term
What is a group of axons in the PNS called?
Anything help hold it together?
Definition
Nerves.
Held together by CT
Term
Where would a track be found?
Definition
In the brain! Trackin w/ me?
Term
The nerve of those gangs! What do Nerves and Ganglia have in common?
Definition
Both are found in the PNS
Term
Nuclei Tracks.... What is the common factor between these two?
Definition
Both are part of the CNS.
Term
PNS Nerve Coverings:
What is the CT covering INDIVIDUAL Axons?
Definition
Endoneurium
Term
PNS Nerve:
What is a fascicle?
Definition
A group of axons
Term
PNS Nerve Coverings:
What is the CT around a fasicile (group of axons) called?
Definition
Perineurium
Term
CNS Nerve Covering:
What is the CT the covers the ENTIRE Nerve? What does it contain?
Definition
Epineurium, containing the blood supply and adipose.
Term
What are the 2 ways to classify neurons?
Definition
Structural and Functional
Term
What are the 3 functional classifications of neurons
Definition
Afferent (arrives) AKA Sensory
Efferent (exits) AKA Motor
Interneurons AKA association - most common b/t sensory & motor neurons
Term
Where would an efferent neuron be going??
Definition
To a muscle or gland
Term
Where would an Afferent gland be going? From?
Definition
CNS from receptors
Term
WHat are the 3 structural classifications of Neurons?
Definition
BiPolar
MultiPolar
UniPolar
Term
Explain a bipolar structural classification.
Where is it found?
Definition
Rare - a process is at either end and is for special senses like nose, ears and retina.
Term
Explain Multipolar classification of a neuron.
Definition
Most popular. A cell with one process (axon end) and many dendrites.
Term
Explain the Unipolar classification of a Neuron
Definition
Most w this structure are sensory neurons. A cell body is in between the dendrites and axon, but off to the side (almost like out of the way on a branch)
Term
How many types of Neuroglia are there?
Definition
six
Term
Can Neuroglia divide?
Can Neurons Divide?
Definition
Neuroglia can, but Neurons can't
Term
What Neuroglia make up 90% of the brain cells? Briefly describe.
Definition
Astrocytes.
Star shaped, make a blood/brain barrier, provide structural support
Term
What is an astrocyte?
Definition
A neuroglia making up 90% of brain cells.
Term
What is the cell that forms the myelin sheath on axons in the PNS
Definition
Schwann Cells AKA neurolemmocytes (means nerve sheath)
Term
What is the function of the neuroglia called oligodendrocytes
Definition
form myelin sheaths around axons in the PNS
Term
What are the names of the Neuroglia cell that migrate around cleanin things up?
Definition
microglia - they are like little scavengers.
Term
What Neuroglia cells surround the lining of ventricles in the brain & C-Canal, forming and circulating CSF?
Definition
Ependymal.
Think epideral - spine
Term
What is a neuroglia satellite cell do?
In PNS or CNS?
Definition
It supports neurons in the PNS
Term
What are the 3 function of an axon sheath?
Definition
Surround
Protect
Insulate axons
Term
What are the 3 function of an axon sheath?
Definition
Surround
Protect
Insulate axons
Term
Which Neuroglia produce myelin sheaths?
Definition
Schwann (PNS) and oligodendrocytes (CNS)
Term
What rests in invagination of oligodendrocytes or schwann cells?
Definition
Unmyelinated cells
Term
What are gaps in between myelinated cells called?
Definition
Nodes of Ranvier
Term
As schwann cells or "oli" cells wrap around and around and around... where does the cytoplasm go?
Definition
It's pushed to the outside
Term
What are the 2 main difference of Schwann and oligodendrocyte cells?
Definition
1 - schwann are in the PNS, "oli" is in the CNS.
2 -Schwanns surround each axon, but Oli forms around several
Term
Why is regeneragtion harder in the CNS than the PNS?
Definition
The CNS has Oligodendrcytes surrounding several axons so regrowth is harder that schwann cells (which individual axons are covered seperately, easier to fix.
Term
How does regeneration occur in the PNS?
Definition
Break down of nissl bodies, degeneration of axon and then schwann cells form a new regeneration tube.
Term
What does Chromatolysis refer to in the regeneration process in the PNS?
Definition
The breakdown of nissl bodies - the 1st step of regeneration
Term
WHen the degeneration of an axon occurs, what is Wallerian and retrograde referring to?
Definition
Wallarian - distal to injury
Retrograde - proximal by 1 axon from injury site
Term
What cells form a regeneration tube in the PNS?
Definition
Schwann cells
Term
What is the function of the regeneration tube made by schwann cells?
How does it tempt the axon?
Definition
The tube is to show the axons where to go to reconnect and it attracts them by secreting a chemical.
Term
Describe divergint converging circuits
Definition
small # of presynaptic cells synapse with many post-synaptic cells
Term
Describe convergant circuits
Definition
Many neurons converge on one post-synaptic cell
Term
Describe Reverberating circuits.
Definition
Neurons arranged in a circle, allowing APs to occur over and over - until fatigue or inhibition
Term
Describe Parallel-After-Discharge Circuit
Definition
a neuron send varying # of synapses taht take several different routes to the same location (post-synaptic cell)
Term
Neurotransmitters:
They are _________ (not vague)
Definition
Specific
Term
Nuerotransmitters:
What does Synaptic Plasticity refer to?
Definition
The ability for a neuron to release more than 1 neurotransmitter
Term
What effects the EPSP or IPSP of a neurotransmitter?
Definition
Receptors on the postsynaptic cell
Term
What is the most common neurotransmitter?
Definition
Ach
Term
What neurotransmitter has been studied in the CNS, ANS, and stimulates skeletal muscles inactivated by cholinesterase (ACHe)
Definition
Ach
Term
Neurotransmitters:
What is the name of modified amino acids?
Definition
Biogenic amines
Term
Nuerotransmitters:
Where do catecholamines come from?
What do they do?
Definition
From Tyrosine
-eliminated by reuptake into synaptic end bulb
-destroyed by COMT and MAO
Term
Neurotransmitter:
Where is dopamine found?
What drug inhibits uptake?
What disease results from deficiencies?
Definition
In the Brain.
Cocaine.
Parkenson's disease
Term
What are the neurotransmitters Epinephrina and Norepinephrine known for? Located?
Definition
ANS and CNS
General arousal
Term
What is seratonin from?
Definition
Tryptophan
Term
What bodily functions is seratonin involved with?
Definition
sleep and mood
Term
What is an SSRI?
Definition
Selective Seratonin Reuptake Inhibitor
Term
What is the most common neurotransmitter in the brain?
Isit inhibilory of exhibitory?
Definition
GABA
Inhibitory
Term
What inhibitory neurotransmitter is found in the spine?
Definition
Glycine
Term
What neurotransmitter is SO Excitiing that it can excite you to Death! (Excitotoxity)
When do we see this?
Definition
Glutamate
In strokes
Term
What are the 4 nuerotranmitters that are amino acids? GGGA
Definition
GABA, Glutamate, Glycine, and Aspartate
Term
What is a nuerotransmitter with 3-40 amino acids linked by peptide bonds? (polypeptides)
Definition
Neuropeptides
Term
What does a Neuromodulator do?
Definition
Modify the effects of neurotransmitters.
Term
Describe the relationship between Substance P and Endorphins
Definition
Substance P is a pain transmitter; Endorphines reduce the pain (like runners high) so, it's the neuromodulator.
Term
What are the 5 changes pharmacology focuses on? (SRRRP)
Definition
-synthesis
-release
-removal
-receptor site
-permeability of membrane.
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