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BIO113/ICCC
Chap 19/Macek-Lachelt
18
Biology
Undergraduate 1
02/27/2012

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Term
Virus
Definition
AN infectious particle incapable of replicating outside of a cell, consisting of an RNA or DNA genome surround by a protein coat [capsid] and, for some viruses, a membranous envelope
Term
Capsid
Definition
The protein shell that encloses a viral genome; it may be rod-shaped, polyhedral, or more complex in shape
Term
Viral envelope
Definition
A membrane derived from membranes of the host cell that cloaks the capsid, which in turn encloses a viral genome
Term
Lytic cycle
Definition
A type of phage replicative cycle resulting in the release of new phasges of the lysis (and death) of the host cell
Term
Virulent phage
Definition
A phage that replicates only a lytic cycle
Term
Restriction enzymes
Definition
An endonuclease [type of enzyme] that recognizes and cuts DNA molecules foreign to a bacterium (such as phage genomes). The enzymes cut a specific nucleotide sequences [restriction sites]
Term
Lysogenic cycle
Definition
A type of phage replicative cycle in which the viral genome becomes incorporated intto the bacterial host chromosome as a prophage, is replicated along with the chromosome, and does not kill the host
Term
Prophage
Definition
A phage genome that has been inserted into the specific site on a bacterial chromosome
Term
Retrovirus
Definition
AN RNA virus that replicates by transcribing its RNA into DNA and then inserting the DNA into a cellular chromosome; an important class of cancer-causing viruses
Term
Reverse transcriptase
Definition
An enzyme encoded by certain viruses (retroviruses) that uses RNA as a template for DNA synthesis
Term
Human Immunodeficiency Virus [HIV]
Definition
The infectious agent that causes AIDS; HIV is a retorvirus
Term
Acquired Immmunodeficiency Syndrome [AIDS]
Definition
The symptoms and signs present during the late stages of HIV infection, defined by a specified reduction in the number of T cells and the appearance of characteristic secondary infections
Term
Provirus
Definition
A viral genome that is permanently inserted into a host genome
Term
Vaccine
Definition
A harmless variant derivative of pathogen that stimulates a host's immune system to mount defenses against the pathogen
Term
Epidemic
Definition
A general outbreak of a disease
Term
Pandemic
Definition
A global epidemic
Term
Viroids
Definition
A plant pathogen consisting of a molecule consisting of naked, circular RNA a few hundred nucleotides long
Term
Prions
Definition
An infectious agent that is a misfolded version of a normal cellular protein, Prions appear to increase in number by converting a correctly folded version of the protein to more prions
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