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Bio Test 2
Harvard Extension School Exam 2
10
Biology
Undergraduate 1
11/08/2016

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Term
Complementary base pairing is due to
Definition
the antiparallel orientation of the DNA strands, the pairing of a purine with a pyrimidine and hydrogen bonding.
Term
If pyrimidines could bind to other pyrimidines, and purines could bind to other purines, what would be the effect on the DNA double helix?
Definition
The width of the double helix would vary rather than being fixed.
Term
Since the stability of DNA is affected by the number of hydrogen bonds, with more
bonds promoting more stability, which of the following double-stranded DNA molecules would likely have the greatest stability? A) A molecule with 20 percent A
B) A molecule with 26 percent G
C) A molecule with 32 percent C
D) A molecule with 38 percent T
E) More information is required to answer this question
Definition
A molecule with 32 percent C
Term
If a mutation changes a C to a T on one strand of a DNA molecule, with a corresponding
change in its complementary strand, which of the following is most likely to be affected? A) The width of the major groove
B) The length of the DNA molecule
C) The nature of protein-DNA interactions
D) The number of pyrimidines in the double-stranded molecule
E) All of the above are equally likely
Definition
The nature of protein-DNA interactions
Term
Which proteins assists in DNA replication of both eukaryotes and prokaryotes
Definition
DNA helicase, Single-strand binding protein and Sliding DNA clamp
Term
If the ori site on the E. coli chromosome is deleted...
Definition
replication will not start.
Term
A set of cells in the intestinal epithelium divides continually in order to replace dead
cells. A microscopic examination of this population of cells would show that most of them...
Definition
are in interphase.
Term
The normal haploid number of a plant species is 28. An individual is found with 55
chromosomes. This individual is most likely
Definition
monosomic
Term
Suppose that a certain mRNA is transcribed at a normal rate in the nucleus, but it is found
at very low levels in the cytoplasm. Which of the following would be the most plausible
explanation for this phenomenon?
A) A defect in the addition of the poly-A tail
B) A defect in ribosome binding
C) A defect in nucleic acid hybridization
D) Overactive transcription termination
E) Removal of the introns
Definition
A defect in the addition of the poly-A tail
Term
Stop codons terminate translation
Definition
by binding a protein release factor, causing hydrolysis of the bond between the
polypeptide chain and the tRNA.
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