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Bio test 4
Test for bio names and stuff
40
Biology
Undergraduate 1
04/21/2010

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Term
Hershey and Chase
Definition
proved DNA is hereditary material
Term
DNA
Definition
Substance of inheritance
Genetic material
located on chromosome
A:T C:G
Term
Erin Chagoff
Definition
compared number and ratio of nitrogenous bases
Term
Rosalind Franklin
Definition
took an x-ray of DNA
Term
Watson and Crick
Definition
Proved DNA was double helix
nobel prize winners
A-T: 2 hydrogen bonds
C-G: 3 hydrogen bonds
Purine + Pyrimidine = just right
Term
Theories of DNA Replication: Conservative
Definition
parent molecule intact, new molecule of new nucleotides; not right
Term
Theories of DNA Replication: Semiconservative
Definition
template model, 1 old 1 new; Right
Term
Theories of DNA Replication:Dispersive
Definition
old and new DNA molecule mixed on all strands
Term
Polypeptide
Definition
to get from DNA to protein
Term
Transcription
Definition
in the nucleas
DNA -> mRNA
Term
Translation
Definition
in the cytoplasm, ribosomes
mRNA -> Protein
Term
Codon:
Definition
triplet of nucleotides that code for a specific amino acid Start condon: AVG Stop condon: UAA, UAG, UGA Condon code is redundant not ambiguous
Term
Redundancy
Definition
several things code for 1 amino acid
Term
ambiguity
Definition
No each triplet codes for only one amino acid
Term
Mutation: Silent
Definition
no affect (GUG ~ GUA: makes same amino acid)
Term
Mutation: Missense
Definition
GU~ GCG causes a change in amino acid
Term
Mutation: Nonsense
Definition
stops whole process of translation turns into a stop codon (Nucleaisis corrects accidental change in existing DNA)
Term
Transcription:
Definition
copying DNA into mRNA
Term
Transcription steps
Definition
Step one: Starts in promoter region [Tata box]
Step two: unwinds one strand becomes the template [Initiation]
Step 3: Strand starts to [elongate]
Step 4: [Termination] making new mRNA strand
Term
t-RNA: anticondons
Definition
Eukaryotes: adds 5' cap and a poly A tail b/c cytoplasm is dangerous
Prokaryotes: goes straight into translation (it can do translation and transcription at the same time)
Term
Translation
Definition
where mRNA becomes protein
Term
Translation Process
Definition
1)E: T-RNA [exits]
2)P: [Polypeptide] chain grows
3)A: transfer RNA, TRNA [Arrives]

Step 1: Initiation- unwind, one strand becomes template
Step 2: Elongation: Codon Recognition
Term
Enzymes: DNA Helicase
Definition
Unwinds the double helix
Term
Enzymes: Topoisomerase
Definition
keeps it from rewinding/overwinding before replication fork
Term
Enzymes: Single Strand Banding Protein
Definition
tacks it up, stabalizing unwound DNA
Term
Enzymes: DNA Polymerase 3
Definition
adds nucleotides to new strand (light blue)
Term
Enzymes: DNA Ligase
Definition
glues all together, fills the gaps, link okazaki fragments and DNA that replicate
Term
Enzyme: DNA Polymerase I
Definition
removes the RNA chunks from RNA primer and replaces with DNA
Term
Enzymes:
Definition
1) DNA Helicase
2) Topoisomerase
3) Single Strand Binding Protein
4) Primase/ RNA Primer
5) DNA polymerase 3
6) DNA Ligase
7) DNA Polymerase I
Term
DNA Replication
Definition
-occurs in interphase (mitosis and meiosis)
-2 DNA strands are antiparallel to each other
-adding nucleotides to the 3' end
[5' => 3']
-Eukaryote: 1 fork per bubble
Term
Virus Structure: Capsid
Definition
outer shell of the virus
Term
Virus structure: Capsomere
Definition
Each subunit of Capsid
Term
Virus Structure: Viral Envelope
Definition
copy hosts gycoprotein
Term
Ways virus can spread:Lytic cycle
Definition
feel symptons of being sick
Virus replicates in cell and lysies (bursts)
Host cell dies

virulent virus: only goes through lytic cycle
Term
Ways a virus will spread: Lysogenic
Definition
Do not feel symptons
Host cell lives

Temperate virvs: goes throug lytic and lysogenic cycle
Term
Provirus vs. Retrovirus
Definition
Provirus: viral insertaion (ex: herpes)
Retrvirus: goes from RNA-> DNA (quick mutation)
Ex: HIV leading cause of death
-Zambia highest infect rate
Term
Viroids
Definition
only infect plants
Spread
Horizontal: insects gardening tools
Vertical: from parent
Term
Prions
Definition
misfolded protein
-replicate by contact
Ex: mad cow disease (10 year incubation period)
Term
Messelson and Stahl
Definition
proved the semiconservative model correct
-medium use: ecoli
Term
Needed for Hardy-Weinburg
Definition
large population
no mutations
random mating
no migration
no natural selection
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