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Bio// Mitosis & meiosis
cell reproduction
39
Biology
9th Grade
01/07/2009

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Term
Chromatin
Definition
DNA & protein in the nucleus of a nondiving cell; in interphase.
Term
Chromosomes
Definition
DNA & protein in the nucleus of a dividing cell; mitosis and meiosis.
Term
Chromatid
Definition
One of two identical halves of chromosomes. Two identical chromatids are called sister chromatids.
Term
Centromere
Definition
Structure that serves as point of attachment for the two sister chromatids.
Term
Centrioles
Definition
Organelle in animal cells that helpsorganize organic spindle fibers; mitosis and meiosis.
Term
Spindle fibers
Definition
Protein tubules that attach to the chromosomes and move them during mitosis and meiosis.
Term
Cell cyle
Definition
The events that occur in the life of a cell.
Term
Mitosis
Definition
Asexual reproduction in somatic (body) cells that produces two diploid daughter cells identical to the mother cell.
Term
Meiosis
Definition
Division of the nucleus that produces four haploid daughter cells. Occurs in gametes.
Term
Meiosis I
Definition
Division in which homologous chromosomes are separated. Creates two haploid cells, which then go through meiosis II.
Term
Meiosis II
Definition
Division in which sister chromatids are pulled apart to produce (in total) four haploid daughter cells. 
Term
Cytokinesis
Definition
The physical divsion of the cell into two separate daughter cells. Comes after mitosis/meiosis and is part of the M phase.
Term
Interphase
Definition
The time between the "birth" of a cell and its reproduction. Contains the Gap1 phase, S phase, and G2 phase.
Term
Gap1 phase
Definition
Also called G1. Contains most of the growth cycle for cells.
Term
S phase
Definition
S stands for Synthesis. Contains the replication of a cell's DNA in preparation for mitosis/meiosis.
Term
Gap2 phase
Definition
Also called the G2 phase. When the cell prepares for mitosis/meiosis.
Term
M phase
Definition
Mitosis & cytokinesis.
Term
Homologous chromosomes
Definition
Chromosomes that are similar in size, shape, and location of the centromere. Hold corresponding genes in corresponding locations. One is inherited from the mother, the other from the father.
Term
Haploid
Definition
(N). A cell with only one chromosome from each homologous pair.
Term
Diploid
Definition
(2N). A cell with both chromosomes from each homologous pair.
Term
Gametes
Definition
Diploid. Sexual reproductioan cells. ie, sperm, egg.
Term
Synapsis
Definition
Process of pairing homologous chromosomes. Occurs in Prophase I in meiosis I.
Term
Tetrad
Definition
Homologous chromosomes that are intertwined. Prophase I (meiosis I).
Term
Crossing over
Definition
Exchange of corresponding genes in homologous chromosomes in a tetrad. Encourages genetic variation.
Term
Cancer
Definition
When a cell mutates and fail to respond to cyclins. It divides too quickly and too often, resulting in daughter cells with the same mutation.
Term
Polar Bodies
Definition
Three of the four daughter cells produced in female meiosis. They receive little cytoplasm and disintegrate. The other cell becomes an egg.
Term
Tumor
Definition
A clump of cancer cells. Can be benign or malignant.
Term
Benign
Definition
A tumor that is unlikely to spread.
Term
Malignant
Definition
A tumor that is likely to spread, ie, through bloodstream or lymph system.
Term
Metastasis
Definition
The process wehre cancer spreads from one part of the body to another. Usually throughbloodstream or lymph fluid.
Term
Apoptosis
Definition
Programmed cell death. Usually after they have divided a number of times. Cancer cells use an exzyme (telomerase) to prevent this and divide indefinitely.
Term
Checkpoints
Definition
Places where it is determined if the cell cycle should proceed. Three important ones: between G1 & S, between G2 & M, between metaphase and anaphase. Checks for size, genetic information duplicated, no mutations, chromosomes connected to spindles, etc.
Term
Cyclins
Definition
Cyclins act as control switches that cause the cell to move through phases; eg. assembly of mitotic spindle, breakdown of nuclear membrane, formation of chromosomes from chromatin, separation of sister chromatids, etc.
 
They activate CDKs (cyclin dependent kinases - enzymes) that speed up specific proceeses necessary for the cell cycle.
Term
Give a difference btween cytokinesis in plant and animal cells.
Definition
Plant cells have a cell plate; animal cells "pinch off"
Term
Mitosis; prophase
Definition
» Chromatin condesnes to form chromosomes.
» spindle fibers from "bridge" across cell.
» Nucleolus & nuclear membrance break down.
Term
Mitosis; metaphase
Definition
» Spindle fibers move chromosmes to equator of cell.
Term
Mitosis; anaphase
Definition
» sister chromatids of a chromosome pulled apart and become chromosomes.
» spindle shortens
» new chromosomes move toward opposite ends of cell.
Term
Mitosis; telophase
Definition
» Chromosomes stsart to uncoil to form chromatin.
» Nucleoli & nuclear membrances reform.
» Spindle fibers break down.
» Cytokinesis has already begun.
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