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Bio Ch. 16
Biology Eighth Edition Vocab
13
Biology
Undergraduate 1
11/14/2010

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Cards

Term
James Watson and Francis Crick
Definition

Introduced an elegant double-helical model for the structure of DNA.

(Kidna stole it from the Franklin girl)

Term
DNA
Definition
directs teh development of biochemical, anatomical, physiological and (to some extent) behavioral traits
Term
DNA in heridty was first discovered...
Definition
by studying bacteria and the viruses that infect them
Term
Frederick Griffith in 1928
Definition

- worked with two strains of a bacterium, one pathogenic and one harmless

- Mixed heat-killed remains of the pathogenic strain with living cells of the harmless strain, some living cells became pathogenic.

Term
Transformation
Definition
Now defined as a change in genotype and phenotype due to assimilation of foreign DNA
Term
Oswald Avery, Maclyn McCary and Colin MacLeod
Definition

- Announced that the transforming substance was DNA

- Conclusion was based on experimental evidence that only DNA worked in transforming harmless bacteria into pathogenic bacteria.

Term
Bacteriophages (or phages)
Definition

- Viruses that are widely used in molecular genetics research

- Helped further the study of DNA as a genetic material

Term
Alfred Hersey and Martha Chase
Definition

- performed experiments showing that DNA is teh genetic material of a phage known as T2.

- Concluded that the injected DNA of the phage provides the genetic information

Term
Erwin Chargaff 1950
Definition

- Reported that DNA composition varies from one species to the next

- Chargaff's rule state that in any species there is an equal number of A and T bases, and an equal number of G and C bases

Term
Maruice Wilkins and Rosalind Franklin
Definition

- Used a technique called X-ray crystallography to study molecular structure

- Franklin produced a picture of the DNA molecule using this technique

Term
DNA's Crystallographic images
Definition

- Enabled Watcson to deduce that DNA was helical

- Enabled Watson to deduce teh width of the helix and the spacing of the nitrogenous bases

 

Term
Double Helix
Definition
Width suggested that the DNA molecule was made up of two strands
Term
DNA Composition
Definition

- T pairs up with A

- G pairs up with C

- Adenine and Guanine are double helicals

- Purine with a pyrimidine resulted in a uniform width consisten with the X-ray

- In DNA repication, the parent molecule unwinds, and two new daughter strands are built based on base-pairing rules

 

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