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Bio 93 Final
UCI
25
Biology
Undergraduate 1
12/02/2011

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Term
Genome
Definition
the genetic material of an organism or virus
Term
Cytokinesis
Definition
the division of the cytoplasm to form two separate daughter cells immediately after mitosis, meiosis I, or meiosis II
Term
Mitotic (M) Phase
Definition
the phase of the cell cycle that includes mitosis and cytokinesis
Term
Interphase
Definition
the period in the cell cycle when the cell is not dividing. accounts for about 90% of the cell cycle.
Term
G1 Phase
Definition
the first gap, or growth phase, of the cell cycle, consisting of the portion of interphase before DNA synthesis begins
Term
G2 Phase
Definition
the second gap, or growth phase, of the cell cycle, consisting of the the portion of interphase before DNA synthesis begins
Term
S Phase
Definition
the synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated
Term
Prophase
Definition
the first stage of mitosis, in which the chromatin condenses into discrete chromosomes visible with a light microscope, the mitotic spindle begins to form, and the nucleolus disappears but the nucleus remains intact
Term
Prometaphase
Definition
the second stage of mitosis, in which the nuclear envelope fragments and the spindle microtubules attach to the kinetochores of the chromosome
Term
Metaphase
Definition
the third stage of mitosis, in which the spindle is complete and the chromosomes, attached to microtubules at their kinetochores, are all aligned at the metaphase plate
Term
Anaphase
Definition
the fourth stage of mitosis, in which the chromatids of each chromosome have separated and the daughter chromosomes are moving to the poles of the cell
Term
Telophase
Definition
the fifth and final stage of mitosis, in which daughter nuclei are forming and cytokinesis has typically begun
Term
Mitotic Spindle
Definition
an assemblage of microtubules and associated proteins that is involved in the movement of chromosomes during mitosis
Term
Centrosome
Definition
a structure present in the cytoplasm of animal cells that functions as a microtubule-organizing center and is important during cell division; has two centrioles
Term
Aster
Definition
a radical array of short microtubules that extends from each centrosome toward the plasma membrane in an animal cell undergoing mitosis
Term
Kinetochore
Definition
a structure of proteins attached to the centromere that links each sister chromatid to the mitotic spindle
Term
Cell Plate
Definition
a membrane-bounded, flattened sac located at the midline of a dividing plant cell, inside which the new cell wall forms during cytokinesis
Term
Binary Fission
Definition
a method of asexual reproduction by "division in half"
Term
G0 Phase
Definition
a non-dividing state occupied by cells that have left the cell cycle, sometimes reversibly.
Term
Cyclin
Definition
a cellular protein that occurs in a cyclically fluctuating concentration and that plays an important role in regulating the cell cycle
Term
Cyclin Dependent Kinases
Definition
a protein kinase that is active only when attached to a particular cyclin
Term
MPF
Definition
maturation-promoting factor; a protein complex required for a cell to progress from late interphase to mitosis
Term
Growth Factor
Definition
a protein that must be present in the the extracellular environment for the growth and normal development of certain types of cells
Term
Density-Dependent Inhibition
Definition
the phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another
Term
Anchorage Dependence
Definition
the requirement that a cell must be attached to a substratum in order to initiate cell division
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