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Bio 414 Exam 2 Proteins
Endomembrane, Cytoskeleton, Cellular Movement, Phagocytes in Immunity and Cell-Cell Communication
35
Microbiology
Undergraduate 4
02/24/2018

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Term
(E-)Cadherins
Definition
Connect to other cadherins outside the cell wall
Term
Catenins α and β
Definition
Link cadherin to actin
Term
Connexin
Definition
Monomer for gap junction channels
Term
Elastin
Definition
Fibers crosslinked by lysines to form a net in the extracellular matrix
Term
Proteoglycans
Definition
Long sugar chains added to protein provide stability as in cartilage extracellular matrix
Term
Adhesive Glycoproteins
Definition
Secreted by the cell as part of the extracellular matrix
Term
Fibronectins
Definition
Long fibrils that connect cell to extracellular matrix
Term
Laminins
Definition
Connect to integrins, form the basal lamina
Term
Integrins
Definition
Integral membrane proteins that bind fibronectins/laminins outside the cell to actin inside the cell
Term
Tau
+TIP
Definition
Microtubule stabilizing proteins
Term
Catastrophin
Definition
Microtubule destabilizing proteins
Term
Formin
Profilin
WASP (branching)
Arp2/3 (branching)
Definition
Microfilament growth promoting proteins
Term
Thymosin β4
Gelsolin
CapZ
Definition
Microfilament growth preventing proteins
Term
Filamin
Definition
Microfilament crosslinking proteins (e.g. filopodia)
Term
Fascin
α-actin
Definition
Microfilament bundling proteins (e.g. lamellipodia, cell cortex)
Term
Fimbrin
Villin
Definition
Microfilament binding proteins - binding actin bundles to each other
Term
Myosin I
Calmodulin
Definition
Microfilament binding proteins - binding microfilaments to membrane
Term
Myosin II
Spectrin
Ankryn
Definition
Microfilament binding proteins - binding microfilaments bundles to cell body (as in cell shape)
Term
Myomesin
Definition
Anchors myosin to M line in sarcomeres
Term
Titin
Definition
Anchors thick filaments to Z line in sarcomeres
Term
Tropomyosin
Definition
Blocks myosin-actin bridging, stabilizes thin filament
Term
Tropomodulin
CapZ
Definition
Caps thin filament ends
Term
α-actin
Nebulin
Definition
Forms Z line
Term
Troponin, TnC Subunit
Definition
When bound to calcium, pulls other protein away to allow myosin-actin bridging
Term
IL-1β
TNF-α
IL-6
CXCL8
oIL-12
Definition
Pro-Inflammatory Cytokines
Term
Claudins
Definition
Proteins for paracellular (between two cells) transport
Term
Occludins
Definition
Proteins which stitch tight junctions together like thread
Term
Caveolin
Definition
Like clathrin, but for small vesicles
Term
COP 1 and 2
Definition
Like clathrin, but for transition and secretory vesicles
Term
Dynamin
Definition
Protein which cuts a forming vesicle from the membrane
Term
Keratin
Vimentin
NF Proteins
Definition
Intermediate filament proteins which strengthen cell shape
Term
Desmin
Definition
Intermediate filament protein which aids in muscle contraction
Term
Lamins
Definition
Intermediate filament proteins which give the nucleus shape
Term
Cytoplasmic Calmodulin
Definition
Activates myosin in smooth muscles to allow contraction in the presence of calcium
Term
Selectins
Definition
Adhesion proteins which bind certain proteins to specific cells temporarily
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