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| ability to promote change or do work |
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| due to structure or location |
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| energy in molecular bonds |
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| difference in ion concentration |
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- Law of conservation of energy - Energy cannot be created nor destroyed - Can be transformed from one type to another |
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| First law of thermodynamics |
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| transfer or transformation of energy from one form to another increases entropy or degree of disorder of a system |
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| Second law of thermodynamics |
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| usable energy + unusable energy |
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| Energy transformations involve an increase in... |
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| a measure of the disorder that cannot be harnessed to do work |
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| free energy or amount of energy for work |
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| entropy or unusable energy |
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| absolute temperature in Kelvin |
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| occur without input of additional energy |
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| Key factor is the free energy change |
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| agent that speeds up the rate of a chemical reaction without being consumed during the reaction |
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| protein catalysts in living cells |
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| RNA molecules with catalytic properties (discovered in 1980s) |
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| allows molecules to get close enough to cause bond rearrangement |
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| where bonds are stretched in activation energy |
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| stretched to bond with other molecules |
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1. Large amounts of heat 2. Using enzymes to lower activation energy |
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Definition
| How to overcome activation energy |
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| Location where reaction takes place |
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| reactants that bind to active site |
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| formed when enzyme and substrate bind |
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| specificity for a substrate |
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| plateau where nearly all active sites occupied by substrate |
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| Velocity of reaction near maximal rate (amount of product per unit) |
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| Substrate concentration at which velocity is half maximal value = 1/2 V max |
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| molecule binds to active site; inhibits ability of substrate to bind; Km increases - more substrate needed |
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| Lowers V max without affecting Km; inhibitors binds to allosteric site |
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| small molecules (non-protein) permanently attached to the enzyme |
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| usually inorganic ion that temporarily binds to enzyme |
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| organic molecule that participates in reaction but left unchanged afterward |
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| Result in breakdown and are exergonic |
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Promote synthesis and are endergonic Must be coupled to exergonic reaction |
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1. Substrate-level phosphorylation 2. Chemiomiosis |
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| Electron removed from one molecule is added to another |
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| Cells synthesize molecules only when needed |
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| Molecules are broken down when needed for energy or no longer required |
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1. Gene regulation 2. Cellular regulation 3. Biochemical regulation |
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| Regulation of metabolic pathways |
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| time for 50% of molecules to be broken down |
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| protein that attaches to unwanted protein |
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| Nicotinamide adenine dinucleotide phosphate |
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Definition
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| Nicotinamide adenine nucleotide |
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| process by which living cells obtain energy from organic molecules |
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| Primary aim to make ATP and NADH |
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| can occur with our without oxygen |
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1. energy investment 2. cleavage 3. energy liberation |
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| With large amounts of ATP, ATP will bind to allosteric site in phosphofructokinase, which makes enzyme inactive, thus preventing the breakdown of glucose |
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| Breakdown of pyruvate to an acetyl group |
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| Oxidative phosphorylation |
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| Electron transport chains |
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| group of protein complexes and small organic molecules embedded in the inner mitochondrial membrane |
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| help move things efficiently without requiring energy |
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| chemical synthesis of ATP as a result of pushing H across a membrane |
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| damage DNA; can cause mutation |
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| Chemical reactions occur here... |
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| result in breakdown and are exergonic |
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| promote synthesis and are endergonic; must be coupled to exergonic reaction |
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| for environments that lack oxygen or during oxygen deficits |
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1. use substance other than O2 as final electron acceptor in electron transport chain 2. produce ATP only via substrate-level phosphorylation |
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Definition
| 2 strategies of anaerobic respiration |
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| Donates e- and forms free radicals |
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Definition
| Why is a buildup of NADH problematic? |
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| breakdown of molecules without net oxidation |
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| synthesis and breakdown of molecules with are essential for cell structure and function |
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| synthesis of molecules secondary metabolites that are not necessary for cell structure and growth |
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| phenolics, alkaloids, terpenoids, polyketides |
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| 4 categories of secondary metabolites |
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| antioxidants with intense flavors and smells |
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| bitter-tasting molecules for defense |
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| energy within light is captured and used to synthesize carbohydrates |
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| Calvin cycle and light reaction |
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| two processes of photosynthesis |
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| regions on the surface of the Earth and in the atmosphere where living organisms exist |
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| must eat food, organic molecules from their environment, to sustain life |
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| make organic molecules from inorganic sources |
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| use light as a source of energy; green plants, algae cyanobacteria |
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| majority of photosynthesis occurs in leaves in this part of a leaf |
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| carbon dioxide enters and oxygen exits leaf |
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| organelles in plants and algae that carry out photosynthesis |
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| third membrane of the chloroplast; contains pigment molecules |
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| fluid filled region between thylakoid membrane and inner membrane |
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| occurs in stroma; uses ATP and NADPH to incorporate CO2 into organic molecules |
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| type of electromagnetic radiation; travels as waves; also behaves as particles- photons |
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| captured light energy can be transferred to other molecules to ultimately produce energy intermediates for cellular work |
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| ATP and NADPH used to make carbohydrates; CO2 incorporated into carbohydrates |
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