Shared Flashcard Set

Details

Bio 222 Exam 3
Lec 13 somatosensory 2 pain and temp
14
Biology
Undergraduate 4
11/15/2010

Additional Biology Flashcards

 


 

Cards

Term
scanning braille: mechanoreceptors respond differently
Definition
-merkels disk and meissner corpuscle almost exactly mimic braille pattern
Term
pain
Definition
-perception of unpleasant sensations
-does not require activation of nociceptors
-highly individual and subjective
Term
nociception
Definition
activation of nociceptors and associated neural pathways
does not necessarily lead to the perception of pain
Term
nociceptors are not the same as thermoreceptors
Definition
-thermoreceptor axons do not increase firing rate as stimulus becomes noxious
-nociceptor axons start responding when stimulus beomes noxious, firing rate increases as stimulus intensity increases
Term
types of nociceptors
Definition
=free nerve endings of a-delta fibers and unmyelinated C fibers
-Most are polymodal (mech,chem,AND thermal)
-some respond to ONE stimulus (mechanical, chemical, OR thermal)
Term
a-delta and C fibers
Definition
smallest diameters, slowest conduction (low to no myelination)
Term
bradykinin
Definition
-made by enzyme released from damaged cells
-directly activate nociceptors via depolarization thourhg g-protein receptors
Term
ATP
Definition
-made by enzyme released from damaged cells
-directly affects P2x receptors
Term
Potassium (K+)
Definition
released from damaged cells
depolarizes nociceptors
Term
hyperalgesia
Definition
following injury, injury site and surrounding area has increased perception of pain
Term
sensitization
Definition
exposure of nociceptors to products of tissue damage increases their activity and their sensitivity to stimuli
Term
substances that sensitize nociceptors
Definition
1. bradykinin-increases sensitivity of ion channels (e.g. TRPV1)
2. Prostaglandins-made by enzyme released from damaged cells, aspirin inhibits this enzyme
3. Substance P - released from nociceptors, causes swelling of capillaries, causes release of histamine which causes depolarization
Term
First pain vs. Second pain
Definition
First Pain= a-delta fiber (fast,sharp)

Second Pain= C fiber (long lasting, dull)
Term
referred pain
Definition
information from two different pain receptors (e.g. organ and skin) can converge on same pain neuron
Supporting users have an ad free experience!