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BIO 2200 Ch. 3
Microbio Ch. 3
32
Biology
Undergraduate 3
04/28/2009

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Term
What are macromolecules?
Definition
Nucleic Acids-chains of nucleotides connected by a phosphodiester bond
DNA-deoxyribonucleic acid
RNA-ribonucleic acid
Proteins-chains of amino acids connected by a peptide bond
Lipids-3 fatty acids bound to a glycerol backbone
Polysaccharides-chains of sugars connected by a glycosidic bond
Term
Covalent bonds
Definition
strong bonds that bind elements in
macromolecules.
Term
Hydrogen Bonding
Definition
An electrostatic dipole-dipole interaction
Term
What bonds do amino acids in a protein chain use (Nitrogen bases in DNA)?
Definition
Hydrogen bonds;
combined strength of these weak bonds is a lot
Term
All living organisms use these linkages in lipids except for Archea
Definition
Ester linkages
Term
Archea use these linkages in lipids.
Definition
Ether linkages
Term
Name 2 pentoses
Definition
Ribose: backbone of RNA
Deoxyriboes: Backbone of DNA
Term
Name 3 hexoses
Definition
Glucose: energy source; cell walls
Fructose: energy source; fruit sugar
N-acetylglucosamine: component of bacterial cell walls
Term
The only differnce between DNA and RNA
Definition
RNA contains an extra 'O' at the 2' carbon making it very unstable
Term
2 monosaccharides are joined by:
Definition
Glycosidic linkages / bonds
Term
Bonds of cellulose
Definition
beta-1,4-glycosidic bond
Term
bonds of starch
Definition
alpha-1,4-glycosidic bond
Term
what bonds does amylase break?
Definition
alpha-1,4-glycosidic bond
Term
Define amphipathic and give an example of an amphipathic molecule.
Definition
Having both hydrophillic and hydrophobic ends
Term
the amphipathic nature of lipids makes them ideal for
Definition
structural components for cytoplasmic membranes.
Term
Lipids are composed of:
Definition
fatty acids: long hydrocarbon chains with a carboxylic acid at the end.
Term
Triglycerides
Definition
three fatty acids connected to a 3-carbon
glycerol molecule by an ester linkage.
Term
glycolipid.
Definition
A lipid containing a sugar molecule
Term
Pyrimidine bases
Definition
Big name; small structure
Cytosine, Thymine, Uracil
Term
Purine Bases
Definition
Small name-big structure
adenine; guanine
Term
Surages are linked together with what bonds?
Definition
phosphodiester
Term
How many bonds between C & G, between T &A?
Definition
3; 2
Term
What form of the DNA helix is the most common?
Definition
B-form (sheet)
Term
What are the 3 DNA helix forms?
Definition
A, B, and Z
Term
RNA most commonly forms what type of helix?
Definition
A (helix)
Term
Describe the primary structure of peptides.
Definition
sequence of amino acids connected via peptide bond
Term
Describe the secondary structure of peptides.
Definition
arrangement of amino acids in a peptide. (H-bonds: complimentary base pairing).
Term
Describe the tertiary structure of peptides.
Definition
How the motifs fold up on itself (disulfide bonds)
Term
Describe the quaternary structure of peptides.
Definition
how separate polypeptides interact
Term
disulfide bonds
Definition
stabilize the tertiary and secondary protein structures
Term
denaturation
Definition
2 strands coming apart. protein can become active again after gentle denaturation
Term
Secondary, tertiary, and quaternary structures determined by
Definition
primary structure
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