Shared Flashcard Set

Details

BIO 211 Chapter 14
DNA and the Gene: Synthesis and Repair
14
Biology
Undergraduate 2
12/14/2010

Additional Biology Flashcards

 


 

Cards

Term
DNA polymerase III can _______
Definition
repair mismatches bases
Term
UV light causes
Definition
thymine dimers
Term
nucleotide excision repair
Definition
(1) enzymes detect an irregularity and cut damaged strand
(2) enzyme excises nucleotides on damaged strand
(e) DNA polymerase fills in gaps in 5-3 direction
(4) DNA ligase links it together
Term
helicase
Definition
• binds at replication fork
• breaks H-bonds between bases and opens double helix
Term
topoisomerase
Definition
• binds ahead of the replication fork
• breaks covalent bonds in DNA backbone to relive twisting forces cause by opening the helix
Term
single-strand binding protein
Definition
• binds after replication fork
• prevents H-bonds between bases and stabilize single-stranded DNA
Term
leading strand
Definition
only one primer needed
polymerase moves toward replication fork
made continuously
Term
lagging strand
Definition
polymerase moves away from replication fork
made in segments
multiple primers needed
Term
both leading and lagging strand
Definition
synthesized in 5-3 direction
Term
primase
Definition
catalyzes synthesis of RNA primer
Term
DNA polymerase III's role in DNA synthesis
Definition
extends leading strand
Term
sliding clamp
Definition
holds DNA polymerase in place during strand extension
Term
DNA polymerase I
Definition
removes RNA primer and replaces it with DNA
Term
DNA ligase
Definition
catalyzes joining of Okazaki fragments into a continuous strand
Supporting users have an ad free experience!