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Bio 146 Chapter 6
Skeletal System
42
Biology
Undergraduate 2
08/29/2011

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Term
Periosteum
Definition
an outer fibrous layer, inner cellular layer contains sharpeys fibers. Does NOT cover ends of the bone.
Term
Functions of Periosteum
Definition
isolate bone from surrounding tissues,
provide a route for circulatory and nervous supply, participate in bone growth/ repair.
Term
Sharpeys fibers
Definition
Collagen fibers in the periosteum that connect with collagen fibers in the bone joint capsules tendons and ligaments. These fibers are extremely strong. Almost like a braid connecting collagen fibers with fibers in bone etc.
Term
Endosteum
Definition
on the inside lining the medulary cavity can be incomplete. contains osteoblasts, osteoprgenitor cells and osteoclasts.
Is active in bone growth and repair.
Term
Long Bone
Definition
long and thin, found in arms legs hands feet fingers and toes.
Term
Flat Bone
Definition
Long and thin, found in arms, legs, hands, feet, fingers and toes. contain red bone marrow.
Term
Sutural bones
Definition
small irregular bones. can be the size of a grain of sand up to a quarter. found in skull, sternum, ribs and scapula. holds skull together
Term
Irregular Bones
Definition
complex shapes. found only in vertebrae and os coxae (pelvic bone)
Term
Short bones
Definition
small and thick, found in ankle and wrist bones
Term
Sesamoid Bones
Definition
small and flat. aren't born with them. are made by your body due to friction and excess stress. Only named sesamoid bone would be the patella
Term
Diaphysis
Definition
shaft of the bone made of compact bone. also contains the medullary cavity.
Term
Epiphysis
Definition
ends of bone, made of spongy bone, covered with compact bone. where the bone articulates with others.
Term
Metaphysis
Definition
where epiphysis and diaphysis meet.
Term
Red bone marrow
Definition
produces blood cells. when growing you'll see more red than yellow.
Term
yellow marrow
Definition
adipose tissue. when not growing body stores fat in bone cavity as yellow marrow.
Term
Flat bone description
Definition
resembles a sandwhich with spongy bone in the middle and compact bone on the outer layers.
Term
osteogenisis
Definition
bone growth, (formation)
Term
ossification
Definition
process of replacing cartilage with bone.
Term
calcification
Definition
process of depositing calcium salts during ossification.
Term
Endrochondral Ossification
Definition
ossifies bones that originate ans hyaline cartilage (most bones)
interstitial growth – increases length
appositional growth- increases width
Term
step one of endochondral ossification
Definition
1. chondrocytes(cartilage cell) in the center of the hyaline cartilage:
1. enlarge
2. form struts and calcify
3. die leaving cavities in cartilage
4. kind of like a paper machete balloon.
Term
step two of endochondral ossification
Definition
2. Blood vessels grow around the edges of the cartilage.
Perichondrium
osteoblasts produce a layer of superfcicial bone around the shaft which will continue to grow and become compact ( appositional)
Term
step three of endochondral ossification
Definition
3. blood vessels enter cartilage
1. bringing fibroblasts that become osteoblasts
2. spongy bone develops at the primary ossification center
Term
Step four of endochondral ossification
Definition
4. remodeling creates marrow cavity
1. bone replaces cartilage at the metaphyses
2. why do we need a marrow cavity? Need blood cells to keep the body growing.
Term
step five of endochondral ossification
Definition
5. Capillaries and osteoblasts enter epiphyses
1. creating secondary ossification center
2. varies from bone to bone and from person to person
Term
step six of endochondral ossification
Definition
1. cartilage within the joint cavity is articulation cartilage. Protects bone from bone
2. Cartilage at the metaphysis is epiphyseal cartilage
Term
step seven of endochondral ossification
Definition
7. appositional growth
1. compact bone thickens and strengthens long bone with layers of circumferential lammellae
Term
Intramembranous ossification
Definition
also called dermis ossification because it takes place in dermis. produces dermis bones like mandible and clavicle.
Term
First step of intramembraneous ossification
Definition
1. mesenchymal cells (stem cells) aggregate
1. differentiate into osteoblasts
2. begin ossification at the ossification center
3. develop projections called spicules (mesh network growing together)
Term
Second step of intramembraneous ossification
Definition
2. blood vessels grow into area
1. supply the osteoblatsts
2. spicules connect trapping blood vessels inside
Term
third step of intramembraneous ossification
Definition
3. spongy bone develops and is remodeled into
1. compact bone
2. periosteum
3. marrow cavities
Term
Remodeling
Definition
the adult skeleton maintains itself
replaces mineral reserves remodeling
recycles and renews bone matrix involves osteocytes, osteblasts, and osteoclasts
Term
calcitriol
Definition
hromone made in the kidneys helps absorb calcium and phosphorus from digestive tract
synthesis requires vitamin D3 (cholecalciferol)
Term
Vitamin C
Definition
stimulates osteoblast differentiation required for collagen synthesis
Term
vitamin k and b12
Definition
help synthesize bone protiens
Term
vitamin a
Definition
stimulates osteoblast activity
Term
estrogens and androgens
Definition
stimulate osteoblasts
Term
calcitonin
Definition
brings calcium down
Term
parathyroid hormone
Definition
brings calcium up
Term
where is calcium stored
Definition
bones
Term
where is calcium absorbed?
Definition
digestive tract
Term
where is calcium excreted
Definition
kidneys
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