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Bio 1441 Chapter 8
An Introduction to Metabolism
34
Biology
Undergraduate 1
03/27/2012

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Term
Substrate
Definition
The reactant an enzyme acts on.
Term
Energy
Definition
Capacity to cause change.
Term
Metabolism
Definition
The totality of an organism's chemical reactions.
Term
Metabolic Pathways
Definition
Begins with a specific molecule, which is then altered in a series of defined steps, resulting in a certain product.
Term
Catabolic Pathways
Definition
Metabolic pathway that release energy by breaking down complex molecules to simpler compounds.
Term
Anabolic Pathways
Definition
Consume energy to build complicated molecules from simpler ones.
Term
Bioenergetics
Definition
The study of how energy flows through living organisms.
Term
Kinetic Energy
Definition
Energy associated with an object's motion.
Term
Heat (Thermal) Energy
Definition
Kinetic energy associated with the random movement of atoms or molecules.
Term
Potential Energy
Definition
Energy an object possesses due to its location or structure.
Term
Chemical Energy
Definition
Potential energy available for release energy by breaking down complex molecules.
Term
Thermodynamics
Definition
The study of energy transformations that occur in a collection of matter
Term
First law of thermodynamics
Definition
Energy can not be created or destroyed; It can be transferred and transformed.
Term
Entropy
Definition
A measure of disorder
Term
Second Law of Thermodynamics
Definition
Every energy transfer or transformation increases the entropy of the world.
Term
Spontaneous Process
Definition
A process that can occur without an input of energy.
Term
Free Energy
Definition
Portion of a system's energy that can perform work when temperature and pressure are uniform throughout the system, as in a living cell.
Term
Exergonic Reaction
Definition
Proceeds with a net release of free energy (negative delta G).
Term
Endergonic Reaction
Definition
Absorbs free energy from its surroundings (positive delta G).
Term
Energy Coupling
Definition
The use of an exergonic process to drive an endergonic one.
Term
ATP (Adenosine Triphosphate)
Definition
.... its ATP. It makes things happen? Energy.
Term
Phosphorylated Intermediate
Definition
The recipient with the phosphate group covalently bonded to it.
Term
Enzyme
Definition
A macromolecule that acts as a catalyst, speeding up a reaction.
Term
Activation Energy
Definition
The initial investment of energy for starting a reaction.
Term
Enzyme-Substrate Complex
Definition
Formed when an enzyme binds to its substrate.
Term
Active Site
Definition
A restricted region of the enzyme molecule that binds to the substrate.
Term
Induced Fit
Definition
The change in shape making the active site fit more snugly around the substrate.
Term
Cofactors
Definition
Nonprotein helpers required by many enzymes for catalytic activity.
Term
Coenzyme
Definition
An organic molecule cofactor.
Term
Competitive Inhibitors
Definition
Binds to the active site, blocking substrates from entering.
Term
Noncompetitive Inhibitors
Definition
Impede enzymatic reactions by binding to another part of the enzyme.
Term
Allosteric Regulation
Definition
Any case in which a protein's function at one site is affected by the binding of a regulatory molecule to a separate site.
Term
Cooperativity
Definition
A kind of allosteric activation where a substrate molecule binding to one active site in a multisubunit enzyme triggers a shape change, increasing catalytic activity at the other active sites.
Term
Feedback Inhibition
Definition
A metabolic pathway is siwtched off by the inhibitory binding of its end product to an enzyme that acts early in the pathway.
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