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| groups of muscle cells/fibers |
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| long bundles of myofibrils |
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organized into sarcomeres ("contractile unit" of muscles) |
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| cytoplasm of muscle cell; myofibril, myoglobin, glycogen |
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| has T-tubules filled with extracellular fluid |
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| myosin protein binds/hyrolyzes ATP; consists of hundreds of myosin heads (golf club) |
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| two chains of actin protein; each actin unit has an active site that can bind myosin head; tropomyosin blocks active site in relaxed muscles; troponin binds tropomyosin and calcium |
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| movement; communication; stability; control of body openings; heat production |
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| excitability; conductivity; contractility; extensibility; elasticity |
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| voluntary, multinucleate, striated, attached to bone/skin/fascia |
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| involuntary; striated; mononucleate; autorhythmic |
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| involuntary; non-striated; mononucleate; hair follicles/walls of hollow organs |
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| thick filament; partially overlaps with thin filament |
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| contraction of all sarcomeres, in all myofibrils, in all cells... |
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| causes the muscle to contract as a whole |
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| 4 major stages of muscle contraction |
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Definition
1. excitation 2. excitation-contraction coupling 3. contraction 4. relaxation |
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| communication between neuron and mmuscle cell |
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| excitation-contraction (general) |
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Definition
| conversion of action potential in muscle cell to activation of protein in sarcomere |
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| muscles develop tension and may shorten |
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| potassium leaves the cell; but more sodium enters than potassium leaves |
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| end-plate potential (EPP) |
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| action potential; Na+ channels open on motor plate |
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| function of sarcoplasmic reticulum |
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Definition
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| voltage-gated Na+ channels in T tubules are physically to... |
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Definition
| Ca+ ion channels in sarcoplasmic reticulum |
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| calcium released by SR... |
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Definition
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| troponin-tropomyosin complex changes shape and exposes... |
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Definition
| active sites on thin filaments |
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Term
| active transport needed to... |
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Definition
| pump calcium back into sarcoplasmic reticulum |
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Term
| total muscle contraction= |
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Definition
| sum of individual muscle cell contraction |
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