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BIO 110.3
Meiosis, Genetics, and Evolution
39
Biology
Undergraduate 1
11/22/2009

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Cards

Term
Define Gene.
Definition
Unit of heredity. (Sequence of Nucleotides that codes for a single polypeptide.)
Term
Define Locus.
Definition
A gene's specific physical location on a specific chromosome.
Term
How do mutations lead to genetic variability?
Definition
Small changes in DNA lead to the production of different proteins.
Term
Define allele.
Definition

Different versions of a gene.

 

Example: Tongue Rolling v. Flat Tongues

Term
What is the difference between a diploid and a haploid chromosome?
Definition

A diploid chromosome is 2 chromosome sets joined together by a centromere (2n). DNA replication has occured. 

 

A haploid chromosome is only one chromosome set (1n).

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Term
Define homologous pair
Definition

Pair of chromosomes which carry all the same genes in the same loci. (These genes are found NOWHERE else).

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Term
What are the 2 functions of Meiosis?
Definition

1. Turn diploid chromosomes into haploid chromosomes.

2. Promote genetic diversity.

Term
What happens during Prophase I?
Definition

Chromosomes condense. Homologous pairs come together locus to locus (synapsis). Crossing over may occur.

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Term
Define crossing over.
Definition

Reciprocal exchange between homologous pairs.

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Term
What happens during Metaphase I?
Definition

Homologous pairs line up along the metaphase plate (along the equator).

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Term
What happens during Anaphase I?
Definition

Homologous pairs separate and the chromosomes migrate toward the poles.

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Term
What happens during Telophase I and Cytokinesis?
Definition

The cell is transformed from a diploid cell into a haploid cell as the homologous pairs are separated into 2 separate cells.

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Term
What is Independent Assortment and when does it occur?
Definition

Independent Assortment happens during Metaphase I. During this phase, the chromosomes can line up in any order... it's simply luck.

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Term
What is the formula for calculating the number of different combinations which can occur through independent assortment alone?
Definition
2n
Term
Describe Meiosis II.
Definition

Meiosis II is just like mitosis, but 2 haploid cells divide into 4 haploid cells. Because of crossing over and indepentent assortment, the cells are not identical.

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Term
Explain nondisjuction and when it occurs.
Definition

Nondisjuction is when chromosomes fail to separate. This can occur during Anaphase I between homologous pairs or Anaphase II between sister chromatids.

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Term
Define Aneuploidy.
Definition

Condition in which the Zygote has an abnormal number of chromosomes due to nondisjunction (2n+1 or 2n-1).

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Term
Define Parthenogenesis.
Definition

Another reproduction method aside from sexual reproduction. In this case, an unfertilized egg produces an individual through mitosis; however, no evolution can occur because there is no oppurtunity for crossing over and independent assortment.

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Term
Explain Mendel's Law of Segregation
Definition

Each gene pair segrgates during gamete formation, so each gamete receives only one copy of the gene.

AKA Meiosis

Term
Describe the 3 Different Genotypes
Definition

Homozygous Dominant: 2 Copies of the dominant allele present (RR).

Homozygous Recessive: 2 copies of the recessive allele present (rr).

Heterozygous: One copy of the dominant and recessive allele present (Rr).

Term
What is the typical phenotypic ratio for a monohybrid cross?
Definition

3:1

[image]

Term
What is the typical phenotypic ratio for a dihybrid cross?
Definition

9:3:3:1

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Term
Describe Mendel's Law of Independent Assortment.
Definition
Which allele of a gene pair goes into a particular gamete is indendent of where the alleles of another gene pair go. This happens during Metaphase I.
Term
Define incomplete dominance.
Definition

In the heterozygote, neither allele can be fully expressed.

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Term
Define Codominance.
Definition

In the heterozygote, both alleles are fully expressed.

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Term
Define Epistasis.
Definition

One gene influences the expression of another gene at a different locus.

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Term
Define Linked Genes.
Definition

Genes on the same chromosome that tend to be inherited together.

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Term
What is the typical phenotypic ratio for linked genes?
Definition
3:1 because there is only one homologous pair.
Term
What are some of the mechanisms of gene expression?
Definition
Promoters, Repressors, Activators, Alternative Splicing.
Term
What are the 2 types of chromosomes animals have?
Definition
Autosomal and sex chromosomes.
Term
What is an SRY?
Definition
Sex-determining Region on the Y chromosome, tells the body to make gonads instead of ovaries.
Term
Define Sex-Linked Genes.
Definition

Genes which are found exclusively on either the X or the Y chromosome.

Males are hemizygous.

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Term
What did T.H. Morgan's work with fruit flies (Drosophilia melanogaster) support?
Definition
That crossing over was occuring.
Term
What is the equation for the Recombination Frequency?
Definition

Number of Recombinants

Total of Offspring

 

391/2300=0.17=17% Chance of crossing over taking place, and that the genes are 17 map units apart.

Term
Are farther apart or closer together gene more likely to cross over?
Definition

Farther apart genes are more

 likely to cross over because there's more spots for breakage between them.

 

In fact, if the genes are really far apart they begin to ac

 

 t

 a

 s i

 f the

 y are on different chromosomes.

Term
Define population.
Definition

A Localized Group of Individuals of the same species that can interact and interbreed sucessfully.

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Term
Define Gene Pool.
Definition

The genetic make-up of a population. Sum total of all the alleles in the population.

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Term
What allows a population to be in equilibrium?
Definition
If the frequency of alleles does not change from one generation to the next.
Term

F1 Generation: AA 320 Aa 160 aa 20

 

Determine if this population is in equilibrium.

Definition

Genotype#|Gen.Freq|Loci #A|Loci #a

AA 320 | 320/500=.64 | 640 | 0

Aa 160 | 160/500=.32 | 160 | 160

aa 20 | 20/500=.04 | 0 | 40

500  |  500/500=1.00 | 800+200=1000

 

Freq of A allele: 800/1000= .8

Freq of a allele 200/1000= .2

 

F2 : AA .64 Aa .32 aa .04

Same as F1

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