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BI 201 Chapter 10
Vocab
26
Biology
Undergraduate 2
11/26/2012

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Term
Karyotype
Definition
The morphology of the chromosomes of an organism as viewed with a light microscope
Term
Binary Fission
Definition
Asexual reproduction by division of one cell or body into two equal or nearly equal parts
Term
Haploid (1N)
Definition
Having only one set of chromosomes 
Term
Diploid (2N)
Definition
Having two sets of chromosomes
Term
Sister Chromatids
Definition
One of two identical copies of each chromosome, still linked at the centromere, produced as the chromosomes duplicate for mitotic division; similarly, one of two identical copies of each homologous chromosome present in a tetrad at meiosis
Term
Homologous Chromosomes
Definition
a pair of the same kind of chromosome in a diploid cell
Term
The cell cycle
Definition
the repeating sequence of growth and division through which cells pass each generation
Term

G1

Gap Phase 1

Definition
The phase of the cell cycle after cytokinesis and before DNA replication. Primary growth phase of cell.
Term
G2
Definition
the phase of the cell cycle between DNA replication and mitosis. Cell prepares for mitosis
Term
G0
Definition
Stage of cell cycle occupied by cells that are not actively dividing
Term
Mitosis
Definition
Somatic cell division; nuclear division in which the duplicated chromosomes seperate to form two genetically identical daughter nuclei
Term
Interphase
Definition
the period between two mitotic or meiotic divisions in which a cell grows and its DNA replicates 
Term
Prophase
Definition
the phase of cell division that begins when condensed chromosomes become visible and ends when the nuclear envelope breaks down the assembly of the spindle takes place during prophase
Term
Metaphase
Definition
the stage of mitosis or meiosis during which microtubules become organized into a spindle and the chromosomes come to lie in the spindle’s equatorial plane
Term
Anaphase
Definition
In mitosis and meiosis II, the stage initiated by the separation of sister chromatids, during which the daughter chromosomes move to opposite poles of the cell; in meiosis I marked by separation of replicated homologous chromosomes
Term
Telophase
Definition
The phase of cell division during which the spindle breaks down, the nuclear envelope of each daughter cell forms, and the chromosomes uncoil and become diffuse.
Term
Cytokinesis
Definition
Division of the cytoplasm of a cell after nuclear division
Term
Centromere
Definition
A visible point of constriction on a chromosome that contains repeated DNA sequences that bind specific proteins. These proteins make up the kinetochore to which microtubules attach during cell division
Term
Kinetochore
Definition
Disk shaped protein structure within the centromere to which the spindle fibers attach during mitosis or meiosis
Term
MPF
Definition
maturation-promoting factor; a positive regulator of cell cycle progression in the cytoplasm of dividing cells
Term
Cyclins
Definition

Any of a number of proteins that are produced in synchrony with the cell cycle and combine with certain protein kinases, the cyclin-dependant kinases, at certain points during cell division

Term
Cyclin-dependent Kinases
Definition
(Cdk) any of a group of protein kinase enzymes that control progress through the cell cycle. These enzymes are only active when complexed with cyclin.
Term
Oncogene
Definition
A mutant form of a growth-regulating gene that is inappropriately “on,” causing unrestrained cell growth and division
Term
Proto-oncogene
Definition
a normal cellular gene that can act as an oncogene when mutated
Term
Growth Factors
Definition
any of a number of proteins that bind to membrane receptors and initiate intracellular signaling systems that result in cell growth and division
Term
Tumor Suppressors
Definition

A gene that normally functions to inhibit cell division; mutated forms can lead to the unrestrained cell division of cancer, but only when both copies of the gene are mutant.

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