Actos

Pioglitazone

15-45mg/day po

a thiazolidinedione

improves ins sensitivity, by binding PPAR and changing transcription of proteins, reduces hepatic gluconeogenesism,

contraindicated in HF class III and IV

Glucophage

Glucophage XR

Metformin

max dose 2250mg/day

a biguanide, dec glucose absorption in intest, inc ins sensitivity,

contraindicated in men srcr>1.5 wm>1.4

insulin

time to effect

[]=100U/ml

onset/duration

regular o.5-1/6-8

NPH 3-4/24

Humulin 70/30 0.5-1/24

brand names Novolin and Humulin

Levemir

Detemir

long acting

Lantus

glargine

long acting

Novolog

aspart

rapid onset-given w/in 5-10 min of meal

Humalog

Lispro

rapid acting

desyrel

trazodone

depression/sleep

150mg/day  QHS

adv.  priapism 

take w/ food

sinequan

doxepin

TCA

(very sedative)

DDI - MAOI  must wait 2 weeks post MAOI before starting

ADV: lots of antichol effects

Ativan

Lorazepam

for trt of sz, anx disordrs, status epilepticus 4mg then again in 10min

works by inc. inhibitory transmitter (GABA)

valium

diazepam

anxiety disorders or OH w/draw

buspar

buspirone

5-10mg/day

for shortterm relief of anxiety

DDI- MAOI's

contraindicated in hepatic or renal dysfunction

ADV; rare-dystonia, parkinsonism TD (binds DA)

Xanax

Alprazolam

0.25-0.5mg TID

for anxiety/panic disorders

Lyrica

Pregabalin

150mg/day

for neuropathic pain/adjunct sz med/fibromyalgia

Keppra

Levetiracetam

for partial onset sz/and tonic clonic

Neurontin

Gabapentin

900-1800mg/day in 3 doses

for sz, and neuralgia

divalproex

Depakote

trt of sz, mania, bipolar

max dose 60mg/kg

tegretol, Equetrol, Carbatrol

Carbamazepine

sz trt

macrolides = inc []

self metabolizer, also mets valproic acid

Cleocin

Clindamycin

URTI, skin and soft tissue inf. ect

used in penicillin allergies