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BG 12 HTN
BRAND GENERIC
42
Pharmacology
Graduate
03/19/2012

Additional Pharmacology Flashcards

 


 

Cards

Term

 

Micardis

Definition

 

Telmisartan

 

ARB

 blocks angiotensin II receptor = vasodilation and decrease in decreased aldosterone

 

ACE AND ARB may cause neonatal death, C in 1st tri and D in 2nd and 3rd,  rhabdo is rare

Term

 

Micardis HCT

Definition

 

Telmisartan w/ HCTZ

 

ARB w/ diuretic

 

HCTZ may inc lithium levels and is K wasting, HCTZ should not be used in pts allergic to sulfas/gout/impared renal function or hepatic/corticosteroids or ACTH

 

don't use ARB's ACE w/ prego

Term

 

Hytrin

Definition

 

Terazosin Hydrochloride

used for BPH, HTN

 

alpha 1 blocker = dilation of arteries and veins, and relaxes sm in bladder neck and prostate = inc ease of peeing

 

start w/ 1mg tab at bedtime to dec fainting risk

 

prego cat C

Term

 

Diovan

Definition

 

Valsartan

 

ARB for HTN & HF

 

NSAIDS may dec effects and inc risk of renal funtion deterioration

 

contra in prego, be careful w/ hepatic or renal dysfunct

Term

 

Diovan-HCT

Definition

 

Valsartan w/ HCTZ

 

HCTZ don't use w/ sulfa allergy, may inc lithium levels, NSAIDS dec effect and inc risk to kidney & liver

 

ARB don't use w/ prego or nursing

Term

 

Isoptin, calan, verelen

Definition

 

Verapamil HCL

 

nondihydroperidine CCB, most selective for Heart muscle, decreases O2 demand in heart,

contra in pts w/ severe LVHF

 

Term

 

Catapres, catapres TTS

Definition

 

Clonidine

tabs/patch

 

stimulates central alpha rec. = reduced sympathetic outflow from CNS & dec bp, hr, w/ renal flow not affected

 

do not stop catapress or beta blockers suddenly = inc bp

Term

 

Altace

Definition

 

Ramipril

 

ACEI = dec dec angio II, dec aldosterone, dec peripheral resistance, dec bp, tends to inc K,

 

use cautiously w/ K sparing diuretics, may cause lithium toxicity, ANGIOEDEMA, neutropenia, cough

 

 

 

 

Term

 

Accupril

Definition

 

Quinapril

 

ACEI - indomethacin w/ ACEI may dec effects, inc lithium/digoxin toxicity, ACEI gives inc in K

 

use caution w K sparing diuretic, ANGIOEDEMA, neutropenia

Term

 

 

Definition
Term

 

Inderal LA, Innopran XL

 

 

Definition

 

Propranolol

nonselective beta blocker = dec HR & cardiac output, dec bp, inhibits isoproteronol tachycardia, dec orthostatic tachycardia,

 

crosses BBB = used for migraines  

toxic effects increased by verapamil, epinephrine + bb = severe HTN,

dont use in pts w/ asthma, sinus brady cardia, greater than 1st degree heart block, CHF (congestive HF)

Term

 

Benicar-HCT

Definition

 

Olmesartan Medoxomil w/ HCTZ

 

ARB + HCTZ

 

Term

 

Benicar

Definition

 

Olmesartan Medoxomil

ARB

Term

 

Procardia, Mefedical XL, Adalet CC

Definition

 

Nifedipine

 

for angina, HTN

 

dihydroperidine CCB = dilation of coronary arteries, coronary spasm inhibition, dilation of peripheral artery's,

Term

 

Lopressor

Definition

 

Metoprolol Tartrate

beta 1 selective BB = dec HR, and cardiac output, dec bp, inhibits isoproterenol tachycardia, dec orthostatic tachycardia,   used for MI, HTN

 

dont use w CHF, heart block >1st degree, cardiac failure, hr <45bpm bp, or  systolic bp <100

Term

 

Toprol XL

Definition

 

metoprolol succinate

 

BB non selective, lower peaks, and longer time to peak with less peak to trough variation than tartrate

Term

 

Hyzaar

Definition

 

Losartan Potassium w/ HCTZ

 

ARB & HCTZ

Term

 

Cozaar

Definition

 

Losartan

 

ARB

Term

 

Zestoretic, Prinzide

Definition

 

Lisinopril W HCTZ

 

ACE-I

Term

 

Prinivil, Zestril

Definition

 

Lisinopril

 

ACE-I

 

 inc lithium levels, angioedema, increases K, inc risk of hyperkalemia w k sparing meds, dec renal function, DM, may cause liver dx

Term

 

Normodyne, Trandate

Definition

Labetalol Hydrochloride

for HTN

 

non selective BB, with alpha blocker = dilation of arteries and veins, dec cardiac output, no reflex tachycardia!  or dec HR!

50% protein bound

 

alpha 1-vsm constriction, B1-heart, B2-vessels dilation (B2 blockade gives very small vasoconstriction and problem for asthmatics)

Term

 

Avalide

Definition

 

Irbesartan w/ HCTZ

 

ARB + HCTZ

 

 

Term

 

Avapro

Definition

 

Irbesartan

 

ARB

Term

 

Vasotec

Definition

 

Enalapril Maleate

 

ACE-I

for HTN, CHF, left vent dysfunction (asymptomatic)

 

dec ang II = dec aldosterone = dec Na h20 retention,  and angiotensin II is potent vasoconstrictor, give inc in K

 

angioedema, cough, orthostatic HYPOTN

Term

 

Cardura, and Cardura XL

Definition

 

doxazosin Mesylate

 

for HTN & BPH

 

alpha blocker, relaxes sm at bladder neck and prostate,

XL has osmotic push in the pill

 

take 1st dose @ bedtime to avoid fainting, aviod cough and cold meds

Term

 

Cardizem, Cartia, Tiazac

Definition

 

Diltiazem Hydrochloride

 

for HTN & angina, & afib

 

nondihydroperidein CCB, slows SA and AV node conduction, inhibits coronary spasm, lowers bp,

 

Term

 

Coreg, Coreg CR

Definition

 

Carvedilol

 

for HTN, HF, LVdysfunction

 

nonselective BB w/ alpha blocker activity

 

dont use w/ diltiazem or verapamil = conduction probs

Term

 

Atacand

Definition

 

Candesartan Cilexetil

 

ARB-I

Term

 

Ziac

Definition

 

Bisoprolol fumarate w/ HCTZ

 

beta 1 selective BB w/ HCTZ

Term

 

 

Definition
Term
Tenoretic
Definition

 

Atenolol w/ chlorthatlidone

 

beta 1 selective blocker w/ newer thiazide

 

dec hr, dec bp, dec in reflex orthostatic tachycardia, diuretic

Term

 

Tenormin

Definition

 

Atenolol

 

B1 selective bb

 

dec hr, and cardiac output, dec bp, dec orthostatic tachy, dont use in pts w/ >1st degree heart block, sinus bradycardia, cardiac failure

 

Term

 

Norvasc

Definition

 

Amlodipine Besylate

 

better than nifedipine because once daily dosing

 

CCB dihydropiridine

Term

 

Mavik

Definition

 

Trandolapril

 

ACE-I,

for HTN,

 

ANGIOEDEMA, cough, dizzy,

Term

 

apresoline

Definition

 

Hydralazine

 

for HTN

 

effects Ca movement w/in cells = vsm relaxation

Term

 

Monopril

Definition

 

Fosinopril Sodium

 

for HTN, ACE-I,

Term

 

Plendil

Definition

 

Felodipine

 

HTN, CCB dihydropiridine,

Term

 

Lotensin HCT

Definition

 

Benazepril w/ hydrochlorothiazide

 

ACE-I w/ HCTZ

Term

 

Lotensin

Definition

 

Benazepril

 

ACE-I

Term

 

Lotrel

Definition

 

Amlodipine Besylate w/ Benazepril

 

CCB w/ ACE-I

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