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BFP2
Biological Foundations of Psychology (Sem. 2)
334
Biology
Undergraduate 1
01/23/2011

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Term
Ethology
Definition
Animal Behavior
Term
Monogamy among animals is very _______. (___ - ____ %)
Definition
rare
(3 -5%)
Term
Monogamous
Definition
Once a man and woman have mated, they stay together for breeding seasons. (either one or more)
Term
What is an example of a monogamous mammal?
Definition
Prarie Voles
Term
Vasopressin
Definition
a hormone released during copulation (sex)
Term
Where is the vasopressin located in monogamous mammals? (Prarie Voles)
Definition
In monogamous voles, vasopressin receptors are located in the ventral pallidum -> part of the dopamine reward (pleasure) pathway.
Term
The male voles learn to associate the ____ of the specific female with the pleasureable sensation and "thinks": "having sex with this woman is pleasureable!"
Definition
odor
Term
the _______ forming the receptor for vasopressin is encoded by one _____ of the relevant gene.
Definition
protein/allele
Term
Prarie voles have the allele that causes the vasopressin protein to be inserted in the _______ _________ but other vole species do not.
Definition
ventral pallidum
Term
Every mammal has genes to make ______.
Definition
vasopressin
Term
How did scientists discover this specific gene/process?
Definition
Experimentally inserting extra copies of the vasopressin receptor gene => caused: bonding without mating and huddle more closely after mating.
Term
What is the basis of this idea of monogamy?
Definition
based on having this vasopressin receptor.
Term
Cladistics
Definition
greek for "branch" - study of how living things have branched off from each other through evolution.
Term
humans and chimpanzees share 98% of their _______.
Definition
DNA
Term
"A Possible History" (my explanation of slide # 7)
Definition
The superior men make babies with a female and leave her. A man who wants that female comes along and kills those babies in order to make his own babies with that woman. The females become promiscuous in order to protect their babies from these jealous men. Men realize that these women became promiscuous and decide not to leave their women after having babies with them. This process is what could have led to monogamous pairs such as those in the world of prarie voles.
Term
Casualties in Evolution: 2 Causes
Definition
1) Proximate Causes: Genes, Hormones, Nervous System
2) Ultimate Causes: historical pathways, selective processes
Term
Territoriality
Definition
an animals tendency to defend his specific area
Term
territory
Definition
sociographical area than an animal of a particular species consistently defends against con-specifics. (animals = usually involves a nest)
Term
home range
Definition
an area of habitat that is NOT defended
Term
ways of MARKING TERRITORY
Definition
scent marks (pee, poop, rubbing body parts [ex: dogs]) <---- non-violent
Term
territoriality has: 1 - ______ & 2 - ______.
Definition
1. timing.

- "hot seasons" <--- ex: robins that are single = winter; pairs of robins = breeding season

2. gender - related
Term
Territoriality and Testosterone
Definition
ex: male lizards = more threat/energy after testosterone implantation = caused death
Term
Territoriality and Reproduction
Definition
females/floaters ---> related!
Term
Territory Size
Definition
varied among species according to animals size and territories' function. --> ex: new Holland honeyeaters - winter = less territorial (flower abundant) and spring/fall = more territorial (less flowers to eat)

- sugar - water experiment
Term
Explanation of owners winning/ winner takes all
Definition
behavioral dispositions; motivational change ( time changes a situation)
Term
natural selection
Definition
Darwin - variation (mutations), heredity, fitness (differences in reproductive success)
- MUST BE ADAPTIVE!
- genes and culture
Term
Lamarack
Definition
Darwins' biggest competitor
- giraffe idea, one giraffe reached to a high tree, his neck got longer, therefore all giraffes later were born with long necks
Term
sexual selection
Definition
subcategory of natural selection -> personal advantage in mating over others of same species and sex. survival - decreasing rates
Term
group selection
Definition
lemmings, explains altruism ( a selfless concern for the welfare of others ) , problem with this idea, kin selection (hamilton)
Term
Relative investment in reproduction
Definition
-females: invest more energy and resources; eggs (large and costly), gestation, nursing, other feeding.
-males: use less energy and resources; sperm (small and cheap)
Term
Different strategies of effectively passing genes
Definition
-males: fertilize as many females as possible
-females: selective; look for best quality = best kids
Term
If the ratio of ____________ changes, ____________ can change too.
Definition
investment/strategies
Term
Only 10% of mammal species, men stay to help raise kids
Definition
examples: humans, seahorses, and blue-tits
Term
90% of men make babies with the women then _______
Definition
leave
Term
Sexual Harrassment
Definition
- rape is rare in the animal world
-
Term
Social Monogamy does NOT mean Genetic ____________!
Definition
Monogamy
Term
Birds...
Definition
-90% of bird species --> FEMALES chear on male partners... - reasons: fertility insurance, good genes for at least some of her offspring, genetic compatibility, more resources, more protection, less infanticide
Term
What is a territory?
Definition
an area that an animal will defend because it is where they have a nest or a den.It is where they mate, or it has enough food supply for them. M vs. M/F vs. F. Size depends on animals size and function of the territory.
Term
What is a home range?
Definition
an unprotected area/territory
Term
How does an animal gain control of a territory? ("Territoriality")
Definition
not through a fight... but through a noticeable display: visual (red breast robin), auditory, scent marks (urination, defecation, rubbing body parts)
Term
What is a "hot season"
Definition
a time when different animals are territorial
ex: robin pairs - during breeding season; robin individuals: during winter; nectarivores = in the mornings only
Term
A "hot season" is the time in which animals are doing what?
Definition
reproducing. Animals that own a territory reproduce more than those who don't.
Term
What is an Floater?
Definition
An animal that doesn't own a territory - and therefore does not reproduce as frequently as the territory owners. Example: The "Great Tit Floaters" try to build a "secret nest" without being noticed.
Term
What is the hormone that is released when two animals engage in sexual intercourse?
Definition
vasopressin
Term
If an animal is monogamous, where do they have vasopressin receptors?
Definition
in their ventral pallidum. It is part of the dopamine reward/pleasure pathway.
Term
What does it mean when an animal is monogamous/what is an example of one?
Definition
it means that they stick to one partner at a time
ex: prarie voles
Term
If an animal is monogamous then the male associates what of the specific female with pleasure that makes him realize that having sex with this specific person is what gives him pleasure?
Definition
scent
Term
Proximate vs. Ultimate Causes in Evolution:
Definition
Proximate: gene, hormones, nervous system
Ultimate: historical pathways, selective processes
Term
What is Infanticide?
Definition
the process of a mother killing her offspring
Term
What are two examples of infanticidal animals?
Definition
water bugs ( mothers are infanticidal so males guard the eggs)
wattled jacana ( males watch the eggs for 22 -2 4 days but the females will destroy anything laid before that)
Term
What are 3 aspects of Darwin's Natural Selection?
Definition
Variation (mutation), Heredity, and Fitness ( differences in reproductive success)
Term
What are 3 aspects of Darwin's Natural Selection?
Definition
Variation (mutation), Heredity, and Fitness ( differences in reproductive success)
Term
What are 3 aspects of Darwin's Natural Selection?
Definition
Variation (mutation), Heredity, Fitness (differences in reproductive success)
Term
What is sexual selection?
Definition
a subcatergory of natual selection, advantage over others in same species and sex, differential success in reproduction, accounts for survival (decreasing traits)
Term
What are the sexual selection/strategies of bower birds?
Definition
females: eggs (large and costly), gestation, nursing, other feeding; selectively look for quality that will yield best children
Males: Sperm (small and cheap); indiscriminately fertilize as many females as possible
Term
What is a hormone?
Definition
A chemical that is secreted by one cell group.
Term
What is the function of a hormone?
Definition
It travels through the bloodstream to act on cell and tissure targets by promoting increase, growth, and differentiation of cells while also modulating cell activity.
Term
What are the 2 glands that release hormones?
Definition
Endocrine Glands: release hormones within the body
Exocrine Glands: use ducts to secrete fluids such as tears and sweat outside the body
Term
What are 2 Pituitary Glands?
Definition
Anterior Pituitary and Posterior Pituitary
Term
What is the anterior pituitary?
Definition
hormone secreted by thyroid, adrenal cortex, and gonad growth; adenohypophysis (pars tuberalis, pars intermedia, pard distalis)
Term
Hormones released from the hypothalamus are carried to the Anterior Pituitary which in turn releases what?
Definition
Tropic Hormones
Term
What are the 6 tropic hormones released by the Anterior Pituitary?
Definition
Prolaction, Gonadotropic Hormones (FSH, LH), Thyroid - stimulating hormone, ACTH, Growth Hormone,
Term
What is the function of Adrenocoricotropic Hormone (ACTH)?
Definition
controls adrenal cortex and steroid hormone release
Term
What is the function of the thyroid - stimulating hormone (TSH)?
Definition
increases thyroid hormone release
Term
What is the functin of Follicle - Stimulating Hormone (FSH)?
Definition
stimulates egg- containing follicles, or sperm production
Term
What influences gonads?
Definition
gonadotropins
Term
What is the function of Luteinizing Hormone (LH)?
Definition
stimulates follicles to form a corpus luteum
Term
what is a corpus luteum?
Definition
an ovarian structure important in promoting pregnancy
Term
What does prolactin do?
Definition
stimulates lactation in females, and is involved in parental behavior
Term
What is the growth hormone (GH)?
Definition
somatotropin or somatotropic hormone influences growth, mostly during sleep. The stomach hormone ghrelin also evokes GH release.
Term
what is the posterior pituitary responsible for?
Definition
water balance/salt balance, neurohypophysis (infundibular stalk, pars nervosa), hormones (oxytocin/vasopressin)
Term
what is the posterior pituitary responsible for?
Definition
water balance/salt balance, neurohypophysis (infundibular stalk, pars nervosa), hormones (oxytocin/vasopressin)
Term
what is the posterior pituitary responsible for?
Definition
water balance/salt balance, neurohypophysis (infundibular stalk, pars nervosa), hormones (oxytocin/vasopressin)
Term
What is Oxytocin?
Definition
reproductive and parenting behavior... uterine contraction, milk letdown reflex
Term
What does Vasopressin do?
Definition
"Arginine Vasopressin"/"AVP"/antidiuretic hormone "ADH"/increases blood pressure and inhibits urine formation
Term
What are 2 types of chemical communication?
Definition
Neurocrine Communication --> Synaptic/ Endocrine Communication --> a hormone released into the bloodstream to act on target tissues
Term
What are endocrine cells?
Definition
hormones that travel through the bloodstream and go to their target cell tissues
Term
What is Pheromone Communication?
Definition
between individuals of the same species; hormones released into the environment (animals.. dogs)
Term
What is Allomone Communication?
Definition
Chemicals released by one species and affects the behavior of other species (bee and flower)
Term
What are the 5 differences between neuronal and hormonal communication?
Definition
Neuronal: precise destinations, rapid, synaptic cleft is small, digital (all or none), voluntary
Hormonal: throughout the body, slower, meter, analog, involuntary.
Term
What are some general principles of hormone actions?
Definition
1. gradual 2. probability or intensity of behavior 3. multiple effects on several behaviors 4. receptor protein 5. circadian clocks
Term
What is the most important structure involved in homeostasis?
Definition
hypothalamus
Term
What are some inputs to the hypothalamus?
Definition
Nucleus of the solitary tract, reticular formation, retina, circumventricular organs
Term
Nucleus of the Solitary Tract
Definition
visceral sensory informaiton includes blood pressure and gut distention
Term
Reticular Formation
Definition
nucleus of the brainstem, inputs from the spinal cord, ( ex: skin temperature)
Term
Retina
Definition
fibers from the optic nerve to suprachiasmatic nucleus: daylight. Regulates circadian rhythms
Term
Circumventricular Organs
Definition
lack a clood-brain-barrier. This allows them to monitor substances in the blood that would normally be shirlded from neural tissue
Term
two main parts of the pituitary gland (hypophysis)
Definition
anterior and posterior pituitary
Term
Parts of the Anterior Pituitary:
Definition
Pars Tuberalis, Pars intermedia, and Pars distalis
Term
Parts of the Posterior Pituitary
Definition
Infundibullar Stalk and Pars nervosa
Term
Hormone Release VIA the posterior pituitary
Definition
2 parts of the pituitary gland are sperate in function. The pituitary stalk, or infundibulum, connects the pituitary to the hypothalamus. The stalk contains blood vessels and many axons, which only extend to the posterior pituitary.
Term
Regulation of hormones produced by adrenal glands
Definition
the adrenal glands are located on top of each kidney and secrete hormones. IN mammals, the outer 80% of the gland is the adrenal cortex, and the core 20% is the adrenal medulla.
Term
What does the thyroid control?
Definition
how quickly the body burns energy, makes proteins, and how sensitive the body should be to other hormones.
Term
What are the 2 hormones produced by the thyroid glands?
Definition
thyroxine and triidothyronine
Term
What secretes TSH?
Definition
pituitary
Term
What is the release of TSH controlled by?
Definition
negative feedback from blood levels and by thyrotropin-releasing hormone (TRH) from the hypothalamus
Term
The thyronines act on nearly every cell in the body to do what?
Definition
increase the basal metabolic rate, affect preotein synthesis, help regulate long bone growth, neuronal maturation and increase the body's sensitivity to catecholamines such as adrenaline by permissiveness.
Term
What leads to heat generation in humans?
Definition
thyroid hormone
Term
What do Thyroid Hormones contain?
Definition
contain iodine and depend on its supply.
Term
What is a goiter?
Definition
a swelling of the thyroid from iodine difficiency
Term
What can be caused by early thyroid deficiency?
Definition
cretinism (congentinal hypothyroidism) and mental retardation
Term
What is the most effective prevention of mental retardation?
Definition
treatment of thyroid deficiency
Term
What resembles psychiatric disorders?
Definition
endocrine pathology
Term
One type of ADHD involves decreased sensitivity to what?
Definition
thyroid hormone
Term
What can cause depression?
Definition
hypothyroidism
Term
What is Cushing's Disease?
Definition
A result of long - term excess of glucocoricoids ( involved in glucose metabolism), with symptoms of fatigue and depression
Term
What is Cushing's Disease?
Definition
A result of long - term excess of glucocoricoids ( involved in glucose metabolism), with symptoms of fatigue and depression
Term
What is Cushing's Disease?
Definition
A result of long - term excess of glucocoricoids ( involved in glucose metabolism), with symptoms of fatigue and depression
Term
What is Cushing's Disease?
Definition
A result of long - term excess of glucocoricoids ( involved in glucose metabolism), with symptoms of fatigue and depression
Term
What is Cushing's Disease?
Definition
A result of long - term excess of glucocoricoids ( involved in glucose metabolism), with symptoms of fatigue and depression
Term
What happens 6 weeks after conception?
Definition
indifferent gonads become ovaries or testes. Hormones secreted by gonads, mainly testes = direct sexual differentiation
Term
What is the SRY gene and what does it do?
Definition
Sex-determining Region on the Y chromosome --> develops testes: codes for the testes --> determining factor
Term
What happens if there is no SRY present?
Definition
ovary function ( default = female)
Term
What are the 2 early tissues for both male and female structures in each embryo?
Definition
wolffian ducts and mullerian ducts
Term
What do the Wolffian Ducts and Mullerian Ducts connect the gonads to?
Definition
the body wall
Term
What does the Mullerian Duct become in a female embryo?
Definition
fallopian tubes, uterus, and vagina
Term
What does the Wolffian duct become in a Male embryo?
Definition
epididymis, vas deferens, and seminal vesicles; mullerian ducts shrink.
Term
Two hormones from the testes make the system masculine:
Definition
testosterone/Anti-Mullerian Hormone (AMH)
Term
what is the function of testosterone?
Definition
promotes development of the wolffian system; masculanizes structures in the utero ( prostate gland, sctrotum, penis)
Term
What is n5a - reductase?
Definition
an enzyme that converts testosterone into 5a-dihydrotestosterone (DHT) and forms male genatalia
Term
What is the function of the anti-mullerian system (AMH)?
Definition
it induces the regression of the mullerian system
Term
What is Androgen - Insensitivity Syndrome (AIS)?
Definition
defective gene produces abnormal andrgen receptors in an XY fetus; this causes the Wolffian system to not develop The Anti- Mullerian hormone prevents development of the female internal organs but on the outside the person will look female.
Term
In a person with AIS... they have:
Definition
a shallow vagina ( since the mullerian system is responsible for development of the upper 2/3 of the vagina); no ovaries, fallopian tubes or uterus. But strong female gender identity! Many marry an engage in routine female sexual behavior. Difference berween chromosomal sex and gender identity.
Term
Puberty in Males:
Definition
FSH and LH promote increased release of testosterone by the testes. Testosterone promotes developement of male secondary sex characteristics.
Term
Puberty in Females:
Definition
FSH and LH stimulate estradiol production by the ovaries. Estradiol leads to female secondary sex characteristics
Term
What releases the gonadotropin-releasing hormone (GnRH)?
Definition
Hypothalamus
Term
What inhbits GnRH release?
Definition
melatonin
Term
What inhibits melatonin?
Definition
light
Term
What stimulates the release of FSH and LH by the anterior pituitary?
Definition
GnRH
Term
Congenital Adrenal Hyperplasia (CAH)
Definition
exposure of female person (XX genes) to androgens before birth.. causes intersex appearance
Term
Turner's Syndrome
Definition
XO genotype (instead of XX or XY); random (not heritable); normal female appearance but abnormal ovaries = affects fertility. Short stature with folds of skin at neck.. normal intelligence with some spatial and memory deficits
Term
Klinefelter's Syndrome
Definition
XXY genotype; male appearance but needs hormonal treatment at puberty. Normal intelligence with some verbal cognitive difficulties; reduced fertility
Term
The XXY: "Super Male"
Definition
low intelligence, may be violent, fertile but high chance of being abnormal, tall and lean with acne and some physical abnormalities
Term
When does sexual attraction occur/through what?
Definition
Sexual attraction occurs at times of reproduction through odors that reflect the estrogen levels in females and learned associations such as appearance. Appetitive behaviors establish: maintain or perform "ear-wiggling". Male behaviors include staying near the female sniffing, singing, and nest building.
Term
What are estrogens?
Definition
produced at the beginning of the ovulatory cycle and are important for female preceptive behavior.
Term
A female without ovaries with respond perceptively to a combination of what treatments?
Definition
estrogen and progesterone
Term
Testosterone in women is produced by ______. Affect the rate of initiation of a sexual activity by women - but not the rate of receptivity. Affects sexual desire, arousal, and fantasies
Definition
ovaries
Term
brain structures may differ in homosexuals
Definition
some studies from INAH-3 nucleus of the pre-optic area - M>F... unclear if size is result or cause
Term
What are some fetal androgen exposure markers?
Definition
otoacoustic emissions, finger length patterns, eyeblinks, and skeletal features
Term
what is a system for storing and releasing glucose for energy?
Definition
eating
Term
What is the principal sugar used for energy?
Definition
glucose
Term
What is a form of glucose stored for a short term in the liver and muscles?
Definition
glycogen
Term
What is a pancreatic hormone that regulates glycogen?
Definition
insulin
Term
Glucagon
Definition
pancreatic hormone --> mediates glycolysis --> the process of converting glycogen back into glucose when blood glucose levels drop
Term
What spans the cell membrane and interacts with insulin to bring glucose into the cell?
Definition
glucose transporters
Term
Type 1 Diabetes
Definition
autoimmune attack on pancreas beta cells. Glycogen does not enter cells, sweet urine, thirst because of solute imbalance, fatigue, weight loss
Term
Type 2 Diabetes
Definition
middle age, insulin resistance. Gradual decline in amount of insulin produced, risk factor = obesity/high levels of fructose
Term
where are lipids (fats) for long - term storage deposited?
Definition
adipose tissue
Term
what is gluconeogenesis?
Definition
the process of converting fat to glucose and ketones
Term
what are ketones?
Definition
a form of fuel
Term
what else can proteins be converted into?
Definition
glucose
Term
What happens when there is a lesion in the ventromedial hypothalamus (VMH)?
Definition
weight gain and picky eating. May disrupt pathways linking PVN and NST. Result in excess insulin production.
Term
Eating Disorders.. most common to least common
Definition
binge eating, bulimia nervosa, aneorexis nervosa (elevated CART levels)
Term
Circadian Rhythms
Definition
biological rhythm that happens once a day
Term
Ultradian Rhythms
Definition
biological rhythms that happen various times daily
Term
Diurnal
Definition
awake during the day
Term
nocturnal
Definition
awake during the night
Term
Phase shift
Definition
a shift in activity pattern in response to a synchronizing stimulus (food/light)
Term
Entrainment
Definition
process of shifting the rhythm
Term
Entrainment
Definition
process of shifting the rhythm
Term
Zeitgeber
Definition
adjusts circadian rhythms... external cues used to synchronize internal clocks with the environment --> "time-give" (food/light availability)
Term
without external cues of sleep we are on about 25 hour cycles known as:
Definition
"free-running period"
Term
Jet lag
Definition
adjustments to phase delays are easier than phase advances (CA-NY > NY-CA)
Term
SCN --> Suprachiasmatic Nucleus
Definition
Body's Master Internal Clock
Term
What is isolated and maintains a circadian rhythm.. making it independent of zeitgebers?
Definition
SCN tissue
Term
Retinohypothalamic Pathway
Definition
provides information about light through the retinl ganglion cels to the SCN
Term
what keeps track of time independent of light with the internal protein clock
Definition
SCN
Term
Moving of the gene activity and their protein productin and degradation becomes the "ticking of what?
Definition
the internal clock
Term
what are two proteins involved in circadian rhythms?
Definition
Per and Tim
Term
Which cells found in the retinal ganglion cells (RGC) detect light and release glutamate in the SCN? Afterwards, the Glutamate triggers events that promote the production of the Per protein, which in turn shifts the clock and the animal's behavior.
Definition
Melanopsin
Term
Cry (Cryptochrome)
Definition
attaches to Per and Tim proteins
Term
Melatonin
Definition
released only at night by the retina and pineal gland
Term
growth hormone
Definition
released during deep sleep (SWS)
Term
Cortisol
Definition
released mostly in the morning and little throughout the day
Term
What are the biological functions of sleep?
Definition
Energy Conservation, Predator Avoidance, Body Restoration (replenishes metabolic requirements (ex:proteins)), memory consolidation
Term
what is conserved during sleep?
Definition
energy
Term
During sleep, there is a reduction in:
Definition
muscular tension, heart rate, blood pressure, temperature, rate of respiration
Term
neurogenesis occurs when?
Definition
during sleep
Term
effects of sleep deprivation
Definition
difficulty in concentrating, increased irritability, episodes of disorientation
Term
Sleep deprivation diseases compromise immune system and lead to what?
Definition
death
Term
Fatal Familial Insomnia
Definition
inherited// midlife people stop sleeping; die 7 - 24 months later. Caused by prion protein plaques in the anterior and dorsomedial thalamus
Term
Homeostasis
Definition
a physiological state of equilibrium or balance
Term
Homeostasis
Definition
a physiological state of equilibrium or balance
Term
set points
Definition
defended by regulatory systems in order to achieve homeostasis (temp., fluid levels, weight, etc.)
Term
deviation from homeostasis:
Definition
detected by nervous system--> appropiate internal adjustments are made and behavior is designed to motivate the regaining of the ideal state.
Term
what is critical for all biological processes?
Definition
temperature
Term
high temperature disrupts:
Definition
protein function
Term
Low temperature causes:
Definition
slowed reactions; damage to cell membranes except for species that produce "anti-freeze"
Term
temperature regulation
Definition
surface-to-volume ratio
Term
surface area = heat ______
Definition
loss
Term
surface area = heat ______
Definition
loss
Term
volume = heat _______
Definition
generation
Term
what are two ways of maintaing body temperatures?
Definition
ectotherms and endotherms
Term
ectotherms
Definition
amphibians, reptiles, fish; external factors (ex:sunlight)
Term
endotherms
Definition
mammals, birds; internal activity and external factors
Term
Internal (endothermic) responses to cold
Definition
shivering, blood vessels constrict, release of thyroid hormone, activation of brown fat
Term
shivering is caused by :
Definition
muscle twitches which produce heat with the cost of high energy
Term
blood vessel constriction is caused by:
Definition
keeping the blood away from the skin where hear loss is maximal
Term
release of thyroid hormone in response to cold (endothermic) is done by:
Definition
leading to greater overall metabolic activity, warming the body.
Term
Activation of brown fat are:
Definition
fat cells rich with mitochondria, to increase metabolic activity.
Term
Internal (endothermic) responses to heat
Definition
perspiration (cooling the skin through evaporation), humans lose about 1 liter of sweat in an average day, in species that do not perspire, animals may pant or lick their fur. Blood vessels dilate (allowing people more heat loss, causing people to often become very red)
Term
Raynaud's Disease
Definition
blood vessels constriction in response to cold is too extreme, leading to a lack in circulation in affected digits, causing them to appear white
Term
Hyperthermia
Definition
body temperature increases beyond normal limits, causing confusion, faint , sweating ends (above 40 c / 104 f)
Term
Hypothermia
Definition
body temperature decreases beyond normal limits (below 35c/95f(, causing uncontrolled shivering, pain, etc.
Term
in temperatures lower than 31c/87.8f
Definition
pupils dilate, drunkeness behavior, consciousness lost
Term
what has become a common method of reproducing brain damage following cardiac arrest or open heart surgery?
Definition
deliberately producing mild hypothermia
Term
What regulates the internal temperature?
Definition
brain stem, spinal cord, and hypothalamus
Term
Sensitivity: spinal cord = ____/hypothalamus = _____
Definition
about 3 c/ .01 c
Term
What receives input from skin sensors, the spinal cord, and thermo-receptors in it and is overriden by heating/cooling?
Definition
hypothalamus
Term
What are the 2 areas of the hypothalamus that participate in temperature regulation?
Definition
POA and Posterior Hypothalamus
Term
Preoptic Area (POA)
Definition
promotes heat loss: perspiration, dilation of blood vessels
Term
Posterior Hypothalamus
Definition
promotes heat conservation: shivering, constriction of blood vessels
Term
3 types of neurons in the POA
Definition
warm-sensitive, cold-sensitive, temp.-senstive
Term
Warm - Sensitive
Definition
with temp increases their activity increases, also inhibiting cold-sensitive neurons
Term
cold - sensitive neurons
Definition
with temp decrease their firing rate increases. The inhibition from warm-sensitive neurons also decreases
Term
temperature - sensitive
Definition
retain a relatively constant activity level
Term
What do temperature set points possibly reflect?
Definition
a comparison of the activity of temperature - sensitive and insensitive neurons.
Term
What are pyrogens?
Definition
chemical produced by bacteria/viruses that contribute to the production of fever; enter the brain near the hypothalamus, where the BBB is weak; in the POA, they inhibit the activity of warm-sensitive neurons, incrrasing the body core temperature and leading to fever symptoms
Term
Water compartments in the body
Definition
intracellular compartment --> fluid within the cells (67%)/extracellular compartment --> blood (7%), interstitial (26%), CSF (>1%)
Term
solutes
Definition
chemical molecules dissolved in fluid
Term
electrolyte
Definition
a solute that breaks into ions when it is dissolved (sodium, calcium, potassium, chloride)
Term
solution
Definition
fluid containing olutes
Term
2 solutions with equal concentrations of solutes are:
Definition
isotonic
Term
intracellular (high ______) and extracellular (high ______) fluids have different ionic concentraions, their total rrelative concentration of solutes is the same (aka they are isotonic)
Definition
potassium/sodium
Term
What is osmosis?
Definition
the passive movement of water molecules from one place to another
Term
osmotic pressure moves water across a _____________ membrane, along its concentration gradient, from an area with lower concentration of solutes to an area with higher concentration
Definition
semipermeable
Term
an isotonic salt solution is about 0.9% or (__________ _________), the same as mammalian fluids
Definition
physiological saline
Term
an Isotonic chemical solution has:
Definition
2 solutions with EQUAL concentrations of solutes (although the identity of solutes may differ)
Term
A hypotonic chemical solution is:
Definition
a solution with a LOWER concentration of solutes than a reference solution
Term
What is hypertonic chemical solution?
Definition
a solution with a higher concentration of solutes than a reference solution
Term
What is the kidney?
Definition
one of a pair of structures located in the lower back responsible for maintaining fluid balance and for producing urine. Blood enter the kidneys, where it is filtered through the nephrons; impurities and excess water and sodium are removed by the nephrons and send to the bladder for excretion as urine. The filtered blood returns to the circulation
Term
Drowning:
Definition
in freshwater: hypotonic /tear cell membranes
In saltwater:hypertonic/cell dehydration
Term
How many liters of water do humans need a day?
Definition
about 2.5 liters
Term
2 internal cues that trigger thirst:
Definition
osmotic and hypovolemic thirst
Term
osmotic thirst
Definition
cellular dehydration --> increase in the solute concentration of the intracellular fluid/from increase in the solute concentration in the extracellular fluid causing water to leave the cells
Term
Hypovolemic thirst
Definition
low volume --> drops in the VOLUME of the extracecllular fluid
Term
which type of thirst is the most common?
Definition
osmotic thirst
Term
which type of thirst is used as an emergency backup system?
Definition
hypovolemic thirst
Term
Mechanisms of Osmotic Thirst
Definition
blood becomes hypertonic, due to: eating a salty meal, diabetes mellitus. This causes water to leave the cells, in an effort to regain the isotonic state.
Term
what in the brain detects cell dehydration?
Definition
osmoreceptors
Term
The OVLT and Osmoreception
Definition
The OVLT (Organum Vasculosum of the Lamina Terminalis (OVLT) is located near the third ventricle, and includes osmosensory neurons. The BBB is weak in this area. If the fluid surrounding OVLT cells becomes hypertonic (OVLT cells lose water) - their firing rate increases. And if thier surrounding becomes hypotonic - firing rate decreases
Term
Mechanisms of Hypovolemic Thirst
Definition
mostly occurs due to internal bleeding or severe injury. Drops in vlood volume are accompanied by drops in blood pressure. Baroreceptors in blood vessels, the hearty, and the kidneys detect the drop in blood pressure. This initiates the feeling of thirst and causes the kidneys to conserve fluid
Term
Hormones help conserve fluids --> pathway
Definition
osmotic or hypovolemic thirst is sensed --> osmoreceptors/baroreceptors stimulate the posterior pituitary gland to release ADH (vasopressin) --> ADH causes the kidneys to reduce Urine and release Renin --> renin makes the angiotensin II which causes blood vessels to contrict and aldosterone release from the adrenal glands--> aldosterone signals the kidneys to retain sodium
Term
Normal _____ _______ _____ are very important
Definition
blood sodium levels
Term
What can occur if excretion of sodium by the kidneys is inadequate?
Definition
high blood pressure and stroke can occur
Term
Lower than normal sodium levels are a risk to health: true or false?
Definition
true
Term
hyponatremia
Definition
a condition characterized by low sodium and low fluid levels. Can also be caused due to failure of the heart or kidneys, tumors. Leads to nausea, vomiting, cramps, disorientation and can even cause seizures, coma, death. Can occur due to extreme endurance
Term
2 distinct classes of sleep:
Definition
SWS/REM
Term
Slow - Wave Sleep (SWS)
Definition
can be divided into four stages and is characterized by slow - wave EEG activity
Term
Rapid-eye-movement sleep (REM)
Definition
characterized by small amplitude, fast-EEG waves, no postural tension, and rapid eye movements
Term
Electrical brain potentials can be used to classify levels of ______ and states of sleep
Definition
arousal
Term
EEG (electroencephalography)
Definition
records electrical activity in the brain
Term
Electro-oculography (EOG)
Definition
records eye movement
Term
Electromyography (EMG)
Definition
records muscle activity
Term
In a typical night of young adult sleep:
Definition
sleep ranges from 7 - 8 hours, 45-50% is stage 2 sleep/20% is REM sleep . Cycles last 90-110 minutes, but cycles early in the night have more stage 3 and 4 SWS, and later cycles have more REM sleep
Term
As people age, total time asleep declines and number of _____ increases.
Definition
awakenings
Term
Locus Coeruleus (norepinephrine)
Definition
active when awake, less when SWS, silent during REM
Term
Sleep Debt
Definition
accumulation of serotonin in ventrolateral preoptic nucleus of the hypothalamus, eventually deactivating the wakefulness circuits
Term
Adenosine
Definition
throughout the brain - is also related to sleep debt. Caffeine is an adenosine antagonist!!!
Term
Basal Forebrain
Definition
a group of structures near the bottom of the front of the brain, including nucleus basalis, diagonal band of Broca, and medial septal nuclei
Term
Narcolepsy sufferers:
Definition
frequent sleep attacks, excessive daytime sleepiness, do not go through SWS before REM sleep, cataplexy ( loss of muscle tone).
Term
Sleep Paralysis
Definition
brief inability to move just before falling asleep, or just after waking up. May be caused by the pontine center continuing to signal for muscle relaxation, even when awake.
Term
Sleep disorders associated with SWS
Definition
night terrors and sleep enuresis (bed-wetting)... stages 3 & 4 = sleepwalking (somnambulism)
Term
REM behavior disorder (RBD)
Definition
characterized by organized behavior, from an asleep person. it usually begins after age 50 and may be followed by beginning symptoms of Parkinson's disease. This suggests damage in the brain motor systems, or degeneration of the pons.
Term
sleep apnea
Definition
breathing may stop or slow down - blood oxygen drops rapidly.. accompanied by snoring
Term
What may be effective in treating insomnia?
Definition
CBT
Term
Sleeping is associated with:
Definition
REM sleep
Term
Nightmares
Definition
frightening dreams that awaken the sleeper from REM sleep
Term
Night Terrors
Definition
sudden arousals from stage 3 or 4 SWS sleep, marked by fear and autonomic activity- especially prevalent in children
Term
Types of muscles: smooth and striated
Definition
smooth muscles: digestive tract, arteries, reproductive system/striated muscles: cardiac muscles, and skeletal muscles
Term
Skeletal Muscles are made up of:
Definition
individual, long, thin muscle fibers; contain nuclei/exciteable membrane, receptors for acetylcholine (open sodium channels that trigger action potential causing a twitch)
Term
3 types of myosin filament
Definition
type I, 2A, and 2B fibers
Term
Type I fibers (slow twitch)
Definition
legs, back; use aerobic metabplism, participate in endurance movements
Term
Type IIa (medium) and Type IIb (fast twitch)
Definition
arms, shoulders; use anaerobic metabolism, participate in brief, powerful movements
Term
The effects of exercise on muscle
Definition
muscles respond to damage - caused by exercise - by producing more actin and myosin filaments. This increases muscle size, but not matter.
Term
young muscles are more _________ and fiber types are evenly distributed
Definition
angular
Term
muscles can do one thing ________
Definition
contract
Term
the gray matter of the spinal cord is larger in segments serving the arms and legs ue to large numbers of _________ ___________ __________
Definition
alpha motor neurons
Term
a motor unit contains:
Definition
an alpha motor neuron and all the fibers in it
Term
a motor unit includes fibers of only ______ type
Definition
one (I,IIa,IIb)
Term
the size of a motor unit corresponds to its __________
Definition
function
Term
neurons serving type ___ fibers have small cell bodies, innervate few fibers and produce little force
Definition
I
Term
neurons servings type ____ fibers have larger cell bodies, innervate more fibers and produce greater force
Definition
II
Term
a single action potential may be sufficient to produce a _________.
Definition
contraction
Term
______ lasts longer than action potentials, allowing temporal summation
Definition
contraction
Term
To start a movement, alpha motor neurons receive input from:
Definition
muscle spindles, golgi tendon organs, brainstem and motor cortex neurons, spinal interneurons
Term
what provides information about joint position and movement?
Definition
mechanoreceptors
Term
skin receptors are also capable of providing information about __________
Definition
movement
Term
free nerve endings signal pain from extreme ________ positions
Definition
joint
Term
what is a reflex?
Definition
an involuntary response to a stimulus
Term
a reflex involves neurons at the ____ and spinal cord levels
Definition
organ
Term
mono-synaptic reflexes
Definition
require only 2 neurons and a single synapse
Term
poly-synaptic reflexes
Definition
require more than 2 neurons
Term
the withdrawal reflex is also known as the ____ reflex
Definition
flexion
Term
an example of a childhood reflex that becomes inhibited is _________ __________
Definition
babinski sign
Term
What directly affects the activity of muscles?
Definition
alpha motor neurons in the spinal cord
Term
what sends information to alpha motor neurons?
Definition
interneurons and stretch receptors/brain
Term
brain motor control of LATERAL PATHWAY movement:
Definition
- connects the primary motor cortex with the spinal motor neurons
- responsible primarily for fine voluntary movements (ex: tool using)
Term
brain motor control of movement: VENTROMEDIAL PATHWAY
Definition
-originates in the brainstem
- responsible for subconscious, automatic movements of the torso and head
Term
the corticospinal tract
Definition
part of the lateral pathway
cell bodies in the motor cortex
Term
the rubrospinal tract
Definition
part of the lateral pathway; cells from the red (rubro) nucleus, which by themselves receive substantial information from the cortex
Term
the motor cortex in the lateral pathway sends direct ( coticospinal tract) and indirect (rubrospinal tract) information to ____ ______ _____ in the spinal cord
Definition
alpha motor neurons
Term
_________ __________ is the activation of neurons in specific parts of M1 that cause movements of specific body parts
Definition
somatotropic organization
Term
the cerebellum is involved in:
Definition
coordination of various muscles and movements, to provide smooth movements;sequencing and timing of complex movements;body posture
Term
the 3 nuclei of the basal ganglia
Definition
globus pallidus, putamen, caudate nucleus
Term
input to the basal ganglia is through the : _______ and _______
Definition
cortex & substantia nigra
Term
input to the basal ganglia is through the : _______ and _______
Definition
cortex & substantia nigra
Term
output from the basal ganglia is through the:
Definition
motor cortex, thalamus, nuclei of the brain stem that contribute to the ventromedial pathway
Term
does the basal ganglia have any connections with the spinal cord? yes or no?
Definition
no
Term
basal ganglia is involved in movement disorders such as :
Definition
parkinsons and huntingtons
Term
what serves as a "filter" for voluntary movement by having an inhibitory influence on a number of motor systems
Definition
basal ganglia
Term
what is involved in action selection?
Definition
the basal ganglia
Term
the basal ganglia is involved in motor - control and ______.
Definition
learning
Term
the basal ganglia is involved in motor - control and ______.
Definition
learning
Term
what re the 4 ventromedial pathways and where do they originate?
Definition
they originate in various parts of the brainstem...

tectospinal tract, vestibulospinal tract, pontine reticulospinal tract, medullary reticulospinal tract
Term
The motor cortex contains 3 main areas:
Definition
primary motor cortex (M!) --> on the preccentral gyrus. the main source of voluntary motor control. Premotor Area (PMA) and supplementary motor area (SMA)
Term
what part of the brain is responsible for deciding to move?
Definition
prefrontal and parietal cortex
Term
SMA and PMA plan movement, with input from ______ and ____ _______
Definition
thalamus and basal ganglia
Term
________ _________ _______ receives information from SMA and PMA, and from the primary somatosensory cortex
Definition
primary motor cortex
Term
primary motor cortex sends signals via ____ _______ (direct/indirect)
Definition
lateral pathways
Term
lateral pathways activate _______ ________ _______
Definition
spinal motor neurons
Term
alpha motor neurons tell muscles to ________
Definition
contract
Term
movement is encoded by ________ of neurons rather than individual cells
Definition
populations
Term
what is a vector?
Definition
a combination of direction and strength
Term
the direction of the vector is the direction of the ___________, and the length of the vector is the activity strength
Definition
movement
Term
primary motor neurons control movement as a function of cell population activity, rather than as a function of ___ _____ ______.
Definition
single cell activity
Term
neurons in the primary motor cortex encode:
Definition
kinematic and kinetic parameters
Term
neurons in the primary motor cortex encode:
Definition
kinematic and kinetic parameters
Term
kinematic movement parameters
Definition
position, velocity, acceleration, path - i.e.,movement in space
Term
kinetic parameters
Definition
muscle forces and joints rotations (ex: how to produce the movement)
Term
mirror neurons
Definition
discharge when making a movement towards an object & discharge when the observing someone else making the same action towards the same object
Term
human mirror neurons
Definition
active during self - movement or viewing intentional movement of others
Term
Mirror Neurons Systems (MNS)
Definition
imagining or remembering motor acts activates motor areas: primary sensorimotor cortex, dorsal and ventral premotor cortex, lateral cerebellum, basal ganglia
Term
mirror neurons are found in ______ _______
Definition
broca's area
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