Potentiate GABA, an inhibitory neurotransmitter, causing CNS depression.

Withdrawal symptoms when disontinued: can include seizures, insomnia, mental/mood changes, increased reactions to noise/touch/light. N/V/diarrhea, loss of appetite, stomach pain, hallucinations, numbness/tingling of arms and legs, muscle pain, tachycardia, short-term memory loss, and very high fever

L-O-T (lorazepam, oxazepam, and temazepam): these are considered less potentially harmful for elderly or those with liver impairment since they are metabolized to inactive compounds (glucuronides)

Additive effects with sedating drugs, including most pain medicine, muscle relaxants, antihistamine, the antidepressant mirtazapine (Remeron), trazodone, alochol, among others.