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BE310 - Exam 1
Sherwood Ch. 1-5
102
Physiology
Undergraduate 3
09/22/2011

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Term
physiology
Definition
study of the functions of living things
Term
teleological approach
Definition
explains body functions in terms of meeting a bodily need, without considering how this outcome is accomplished
Term
mechanistic approach
Definition
(primary for physiology) mechanisms of action can be explained in terms of cause-and-effect sequences of physical and chemical processes
Term
cell
Definition
basic or fundamental unit of both structure and function in a living being; smallest unit capable of carrying out the processes associated with life
Term
organisms
Definition
independent living entities
Term
anatomy
Definition
study of the structure of the body
Term
cell differentiation
Definition
during development of complex multicellular organisms each cell differentiates, or becomes specialized to carry out a particular function
Term
tissues
Definition
cells of similar structure and specialized function combined
Term
muscle tissue
Definition
consists of cells specialized for contraction and generating force
Term
nervous tissue
Definition
consists of cells specialized for initiating and transmitting electrical impulses, sometimes over long distances
Term
epithelial tissue
Definition
consists of cells specialized for exchanging materials between the cell and its environment
Term
lumen
Definition
cavity within a hollow organ or tube
Term
glands
Definition
epithelial tissue derivatives specialized for secreting
Term
secretion
Definition
release from a cell, in response to appropriate stimulation, of specific products that have been made by the cell
Term
exocrine glands
Definition
secrete through ducts to the outside of the body
Term
endocrine glands
Definition
lack ducts and release their secretory products, known as hormones, internally into the blood
Term
connective tissue
Definition
distinguished by having relatively few cells dispersed within an abundance of extracellular material; connects, supports, and anchors various body parts
Term
organs
Definition
consist of two or more types of primary tissue organized together to perform a particular function or functions
Term
body systems
Definition
collection of organs that perform related functions and interact to accomplish a common activity that is essential for survival of the whole body
Term
internal environment
Definition
watery; the body cells are in direct contact with and make life-sustaining exchanges with
Term
intracellular fluid (ICF)
Definition
fluid collectively contained within all body cells
Term
extracellular fluid (ECF)
Definition
fluid outside of the cells
Term
plasma
Definition
fluid portion of the blood
Term
interstitial fluid
Definition
surrounds and bathes the cells
Term
homeostasis
Definition
maintenance of a relatively stable internal environment
Term
circulatory system
Definition
transport system that carries materials
Term
digestive system
Definition
breaks down dietary food into small nutrient molecules that can be absorbed into the plasma for distribution to the cells
Term
respiratory system
Definition
gets O2 from and eliminates CO2 to the external environment
Term
urinary system
Definition
removes excess water, salt, acid, and other electrolytes from the plasma and eliminates them in the urine, along with waste products
Term
skeletal system
Definition
provides support and protection for the soft tissues and organs; serves as storage for calcium ion
Term
muscular system
Definition
moves the bones to which the skeletal muscles are attached
Term
integumentary system
Definition
serves as an outer protective barrier that prevents internal fluid from being lost from the body and foreign microorganisms from entering
Term
nervous system
Definition
major regulatory system of the body; controls and coordinates bodily activities that require swift response
Term
endocrine system
Definition
major regulatory system; regulate activities that require duration
Term
immune system
Definition
defends against foreign invaders and against body cells that have become cancerous
Term
reproductive system
Definition
not essential for survival, only for procreation
Term
intrinsic (local) controls
Definition
homeostatic control system built into or are inherent in an organ
Term
extrinsic controls
Definition
homeostatic control which are regulatory mechanisms initiated outside an organ to alter the activity of the organ
Term
feedback
Definition
responses made after a change has been detected
Term
feedforward
Definition
response made in anticipation of a change
Term
negative feedback
Definition
change in a homeostatically controlled factor triggers a response that seeks to restore the factor to normal by moving the factor in the opposing direction of the initial change
Term
controlled variable
Definition
factor that can vary but is held within a narrow range by a control system
Term
sensor
Definition
monitors the magnitude of the controlled variable
Term
set point
Definition
desired magnitude of the controlled variable
Term
integrator (control center)
Definition
compares sensor input with the set point and adjusts output
Term
effector
Definition
component of the control system commanded to bring about the desired effect
Term
positive feedback
Definition
output enhances or amplifies a change so the controlled variable continues to move in the direction of the initial change
Term
pathophysiology
Definition
abnormal functioning of the body associated with disease
Term
plasma membrane (cell membrane)
Definition
very thin membranous structure that encloses each cell
Term
nucleus
Definition
the large single organized cell component, distinct spherical structure
Term
nuclear envelope
Definition
double-layered membrane surrounding the nucleus
Term
nuclear pores
Definition
holes in nuclear envelope that allow necessary traffic to move between the nucleus and cytoplasm
Term
deoxyribonucleic acid (DNA)
Definition
fucntions: (1) directing protein synthesis (2) serving as a genetic blueprint during cell replication
Term
ribonucleic acid (RNA)
Definition
play a role in protein synthesis
Term
messenger RNA
Definition
DNA is transcribed into; delivers teh codded message to ribosomes and is translated into amino acid sequence
Term
ribosomal RNA
Definition
essential component of ribosomes
Term
transfer RNA
Definition
transfers the appropriate amino acids within the cytoplasm to their designated site in the protein under construction
Term
cytoplasm
Definition
portion of the cell interior not occupied by the nucleus
Term
cytosol
Definition
remainder of cytoplasm not occupied by organelles
Term
endoplasmic reticulum
Definition
elaborate fluid-filled membranous system distributed extensively throughout the cytosol
Term
smooth ER
Definition
meshwork of tiny interconnected tubules
Term
rough ER
Definition
projects outward as stacks of relatively flattened sacs
Term
ribosomes
Definition
"workbenches" where protein synthesis takes place
Term
transport vesicles
Definition
portions of smooth ER that bud off that contain the new molecules enclosed in a spherical capsule of membrane
Term
vesicle
Definition
fluid-filled membrane-enclosed intracellular cargo container
Term
Golgi complex
Definition
consists of a stack of flattened, slightly curved, membrane-enclosed sacs, or cisternae; process raw materials into finished products and sort and direct the products to their final destinations
Term
docking marker
Definition
each different surface protein marker like an address on an envelope
Term
secretory vesicles
Definition
contain proteins to be secreted
Term
exocytosis
Definition
mechanism of signal a secretory vesicle to release its contents out of the cell
Term
lysosomes
Definition
membrane-enclosed sacs containing powerful hydrolytic enzymes
Term
hydrolytic enzymes
Definition
catalyze hydrolysis reactions
Term
endocytosis
Definition
material being brought into the cell
Term
pinocytosis
Definition
"cell drinking", a small droplet of extracellular fluid is intrnalized
Term
endocytotic vesicle
Definition
structure created when the plasma membrane seals at the surface of a pouch, trapping extracellular contents in small pocket
Term
dynamin
Definition
protein molecule responsible for pinching off an endocytotic vesicle, forms rings that wrap around the wring the neck of the pouch, severing the vesicle from the surface membrane
Term
receptor-mediator endocytosis
Definition
highly selective process that enables cells to import specific large molecules that it needs from the environment
Term
phagocytosis
Definition
"cell eating", large multimolecular particles are internalized
Term
pseudopods
Definition
"false feet", projections from a cells surface that completely surround or engulf the particle and trap it within an internalized vesicle
Term
autophagy
Definition
selective self-digestion
Term
Tay-Saches disease
Definition
characterized by abnormal accumulation of complex molecules found in nerve cells; caused by a missing lysosome enzyme
Term
peroxisomes
Definition
membrane-enclosed sacs containing enzyme which house several powerful oxidative enzymes and contain most of the cell's catalase
Term
oxidative enzymes
Definition
use oxygen to strip hydrogen from certain organic molecules; helps detoxify various wastes within the cell or foreign toxic compounds that have entered the cell
Term
catalase
Definition
antioxidant enzyme that decomposes potent H2O2 into harmless H2O and O2
Term
mitochondria
Definition
energy organelles, "power plants"; extract energy from the nutrients in food and transform it into a usable form for cell activities
Term
cristae
Definition
an inner membrance of the mitochondria that forms a series of infoldings or shelves
Term
matrix
Definition
gel-like solution in the mitochondria
Term
adenosine triphosphate (ATP)
Definition
energy accessible for the cell; stored in high-energy phosphate bonds; consists of an adenosine and three phosphate groups
Term
adenosine diphosphate (ADP)
Definition
adenosine and two phosphate groups
Term
glycolysis
Definition
chemical process involving 10 separate sequential reactions that break down the simple six-carbon sugar molecule, glucose, into two pyruvic acid molecules
Term
tricarboxylic acid cycle (TCA)
Definition
consists of a cyclical series of eight separate biochemical reactions that are directed by the enzymes of the mitochondrial matrix
Term
nicotinamide adenine dinucleotide (NAD)
Definition
hydrogen carrier molecule used in the TCA
Term
flavine adenine dinuceotide (FAD)
Definition
hydrogen carrier molecule used in the TCA
Term
guanosine diphosphate (GDP)
Definition
phosphate receive in TCA
Term
guanosine triphosphate (GTP)
Definition
ATP equivalent made in TCA; high-energy molecule similar to ATP
Term
electron transport chain
Definition
consists of electron carrier molecules located in the inner mitochondrial membrane lining the cristae
Term
chemiosmotic mechanism
Definition
steps in ETS used to harvest energy to create ATP
Term
ATP synthase
Definition
activated by the flow of hydrogen ions from the intermembrane space to the matrix
Term
oxidative phosphorylation
Definition
harnessing of energy into a useful form as the electrons tumble from a high-energy state to a low-energy state
Term
cellular respiration
Definition
the intracellular oxidation of nutrient derivatives
Term
anaerobic
Definition
lack of air
Term
aerobic
Definition
with air
Term
vaults
Definition
shaped like octagonal barrels; cellular "trucks" b/c match the nuclear pores
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