Shared Flashcard Set

Details

b. Control of BP
Local
7
Medical
Graduate
11/14/2012

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Cards

Term
Nam the two major mechanisms of BP control
Definition
Metabolic (metabolites and paracrine ) and myogenic (reflex and endothelial products)
Term
Metabolic control types
Definition
Metabolite (CO2, H+, K+, adenosine)
Paracrine- Ang II, prostoglandins, histamine
Term
Myogenic
Definition
Myogenic reflex- reflexively contract when stretched
Endothelial products (NO)
Term
What is the local control of blood flow?
Definition
-Autoregulation
-Hyperemia- active and reactive
Both myogenic and metabolic
Term
Define autoregulation
Definition
Ability of an ORGAN to maintain constant blood flow during arterial pressure change
-Heart, brain, kidney
Term
What is the blood pressure range for autoregulation of the brain?
Definition
60-180mmHg
Term
How is coronary blood flow regulated?
Definition
-Autoregulation- keep blood flow regardless of pressure change
-Active hyperemia- very sensitive to low adenosine and O2
-Reactive hyperemia- compression during contraction
-Shear stress- NO cause vasodilation
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