Term
| Who discovered the Rh blood group system in 1939? |
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Definition
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Term
| What is the predominant class of anti-D antibodies? |
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Definition
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Term
| Is anti-D an expected antibody? |
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Definition
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Term
| How many antigens are assigned to the Rh system? Of these, how many cause problems? |
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Definition
| 49 total; only 5 commonly cause problems. |
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Term
| Rh positive and Rh negative refers to the presence or absence of what antigen? |
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Definition
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Term
| Who thought that Rh inheritance was three pairs of closely linked genes- D/d, C/c, and E/e? |
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Definition
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Term
| Who decided that Rh inheritance was on one gene with a product that had different epitopes? |
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Definition
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Term
| Who proved that the Rh is two genes- RhD and RhCE? |
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Definition
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Term
| What does 1 or ' stand for? |
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Definition
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Term
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Definition
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Term
| What does 2 or " stand for? |
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Definition
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Term
| What does z or y stand for? |
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Definition
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Term
| Is there any such thing as the d allele? |
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Definition
| No, d is just a spacer used to symbolize a deletion or an inactive gene. |
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Term
| What are the four Rh compound antigens? |
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Definition
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Term
| Which compound antigen is recognized by anti-f? |
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Definition
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Term
| What stage of testing will reveal a weak D? |
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Definition
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Term
| What type blood should a weak D patient recieve? |
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Definition
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Term
| What happens when C is in trans to D? |
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Definition
| steric hindrance causes a weakening of D expression leading to weak D |
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Term
| What blood type is most likely to have a genetic weak D? |
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Definition
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Term
| What is a partial D or mosaic? |
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Definition
| D antigen that only is composed of some of the parts, not all of them. Antibody can be made to the missing parts. |
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Term
| How are Rh antibodies usually stimulated? |
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Definition
| By red cells in pregnancy or transfusion. |
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Term
| How can you enhance Rh reactions? |
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Definition
| enzyme treatment of cells- chews up cell membrane, making Rh antigens more available |
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Term
| Do Rh antibodies show dosage? |
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Definition
| anti-D doesn't; the others do. |
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Term
| property by which antibody reacts more strongly with homozygous expression of antigen than with heterozygous expression |
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Definition
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Term
| Are Rh antigens present on fetal cells? |
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Definition
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Term
| What is it called when a person has no Rh antigens on red cells? |
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Definition
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Term
| What is the most common form of Rh null syndrome? |
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Definition
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Term
| Is supressor Rh null dominant or recessive? |
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Definition
| Recessive. You need 2 supressor genes in order to be Rh null. |
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Term
| What is the rare form of Rh null? |
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Definition
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Term
| When transfusing platelets, D type is often ignored. What kind of patient should only recieve D negative platelets? |
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Definition
| D negative females of childbearing age. |
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Term
| When transfusing granulocytes, should ABO and Rh type be considered? |
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Definition
| Yes; granulocytes must be ABO and D identical or compatible. |
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Term
| When transfusing fresh frozen plasma, should ABO be considered? What about D typing? |
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Definition
| Fresh frozen should be ABO specific or compatible; D type is ignored. |
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