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Bb- ABO system
Test 1
22
Health Care
Undergraduate 4
06/14/2009

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Cards

Term
Who discovered the ABO blood groups and in what year?
Definition
Landsteiner- 1900
Term
How are most blood groups inherited?
Definition
codominant
Term
What is the H gene product?
Definition
L-fucosyltransferase
Term
What is the function of L-fucosyltransferase?
Definition
Adds L-fucose to precursor substance.
Term
Which lectin acts like anti-H?
Definition
Ulex europaeus
Term
What chromosome is the ABO locus on?
Definition
chromosome 9.
Term
What do the A and B enzymes need in order to make the A and B substances?
Definition
H substance.
Term
Which blood group has the least amount of H left, because all of it is converted?
Definition
A1B
Term
At what age are the ABO antigens fully developed?
Definition
2-4 years old
Term
What are the two main groups of A and what percentage are they in the population?
Definition
A1- 80%; A2- 20%
Term
Which one is branched, A1 or A2?
Definition
A1
Term
What is the A1 lectin?
Definition
Dolichos biflorus
Term
How can you determine if someone is type A1 or A2?
Definition
Dolichos biflorus- A1 is agglutinated; A2 is not.
Term
If a person is genetically A1A2, what phenotype are they?
Definition
A1.
Term
What is the most common ABO type?
Definition
O
Term
What is the least common ABO blood type?
Definition
AB
Term
Which is more common, type A or B?
Definition
A
Term
At what age do ABO antibodies appear? At what age do they peak?
Definition
Appear at 4-6 mo., peak at 5-10 years
Term
What is the predominant class of anti-A, -B, and -AB in group O?
Definition
IgG.
Term
What is the predominant class of anti-B in group A and anti-A in group B?
Definition
IgM.
Term
What percentage of A genes are subgroups other than A1 or A2?
Definition
less than 1%
Term
What blood type produces anti-H?
Definition
Bombay (Oh)
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