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BB Exam 4 - Miscellaneous Topics
Lecture 26
39
Biology
Undergraduate 3
03/14/2015

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Term
What is the safest blood to receive?
Definition
Autologous
Term
The inability to give by Autologous is usually due to what?
Definition
Low Hematocrit
Term
What must you confirm before transfusion for an Autologous unit?
Definition
ABO
Rh
Term
True or False
If an autologous unit is not used it can never be used for another person and must be tossed
Definition
True
Term
Describe Intraoperative Hemodilution
Definition
*Once asleep, take out 2 units and replace with IV fluid
*Kept @ RT
*Reinfused @ end of surgery
Term
True or False:
Half of blood lost during surgery or left on extracorporeal circuits can be salvaged
Definition
True
Term
With Intraoperative Blood Salvage, what order are the following performed in:
Reinfuse
Wash RBCs
Suction Site
Collect blood in reservoir containing anticoagulant
Definition
Suction Site
Collect blood in reservoir containing anticoagulant
Wash RBCs
Reinfuse
Term
For whom can Intraoperative Blood Salvage be used?
Definition
Jehovah's Witness
Orthopedic and cardiovascular surgeries
Trauma
Liver Transplants
Splenectomy
Term
Does Intraoperative Blood Salvage increase or decrease allogenic exposures?
Definition
Decrease/Reduces
Term
You should only use Intraoperative Blood Salvage with sterile site free of tumor cells. What area can it not be used?
Definition
Intra-Abdominal
Term
True or False:
Intraoperative Blood Salvage can also be done from drainage tubes after surgery
Definition
True
Term
True or False:
Directed donations are safer than random blood
Definition
False
Term
True or False:
GVHD if family members - irradiate blood
Definition
True
Term
Plasmapheresis -
If donate more often than 1/8 weeks, what must be performed ever four months and be normal?
Definition
SPE
Term
Cytapheresis -
Donate not more than ___/every 48 hours or ____/week, or more than _____ times/year
Definition
once every 48
twice in one week
24 times in a year
Term
Cytapheresis -
RBC loss must not be more than ____/week
Definition
25 mL
Term
Cytapheresis -
RBC loss must be no more than ___ mL / 8 week period
Definition
200 mL
Term
True or False:
Cytapheresis units must be tested to detect cytopenia every 4 months
Definition
True
Term
Cytapheresis units must be tested to detect cytopenia every ___ months
Definition
Four
Term
Cytapheresis units must have a platelet count of more than what?
Definition
150,000/microliter
Term
Cytapheresis -
Extracorporeal volume should NOT exceed ____% of donors' volume
Definition
15%
Term
Transfusions before BMT are _______
Definition
deleterious
Term
BMT - Componenets from whom must be avoided?
Definition
Tissue donor
Immediate Family
Term
True or False:
Transplantation patients create problems for BB when person is in process of changing blood types
Definition
True
Term
BMT - Remove malignant cells with what?
Definition
Monoclonal ABYs
Chemo
Term
What should you do to blood to be given to Transplantation patients in order to reduce alloimmunization?
Definition
Leuko-deplete
Term
What should you remove to prevent GVHD?
Definition
T lymphs
Term
True or False:
Most Transplantation recipients need RBC & ALL need Plts
Definition
True
Term
Use _____ transplantation donor to delay refractoriness, HLA matches, or PLT crossmatch
Definition
One
Term
Now also obtain what to give back later to transplantation patients?
Definition
Autologous peripheral stem cells
Term
Given the procedure list the reason the procedure is used in Marrow Processing:
Remove RBCs
Definition
Prevent hemolysis in Major ABO incompatible BMT
Term
Given the procedure list the reason the procedure is used in Marrow Processing:
Remove Plasma
Definition
Prevent hemolysis in Minor ABO incompatible BMT
Term
Given the procedure list the reason the procedure is used in Marrow Processing:
Remove T lympocytes
Definition
Prevent GVHD
Term
Given the procedure list the reason the procedure is used in Marrow Processing:
Remove Malignant Cells
Definition
Prevent Disease Recurrence
Term
Given the procedure list the reason the procedure is used in Marrow Processing:
Freeze
Definition
Future Auto BMT
Term
Given the Incompatibility list the potential problems:
ABO Major Incompatible
Definition
Hemolysis of RBCs in donor marrow
Term
Given the Incompatibility list the potential problems:
Minor Incompatible
Definition
Hemolysis of patient's RBCs by ABY in marrow
Term
Given the Incompatibility list the potential problems:
Rh
Definition
Hemolysis of patient's RBCs by (donor) ABY produced after engraftment
Term
True or False:
Components transfused post transplantation must match new blood type
Definition
True
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