Term
| Two basic tests of platelet function |
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Definition
| platelet count, bleeding time |
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Term
| what is the capillary fragility test a measure of? |
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Definition
|
|
Term
| a large number of petechiae when doing a capillary fragility test is considered... |
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Definition
|
|
Term
| what would be some causes for an abnormal capillary fragility result? |
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Definition
| thrombocytopenia, von Willebrands disease, vascular defects |
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|
Term
| what is the anticoagulant used for coagulation tests? |
|
Definition
|
|
Term
| which tube draws 9 parts of blood to 1 part anticoagulant? |
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Definition
|
|
Term
| how should a blue top tube full of blood be stored for preservation? |
|
Definition
|
|
Term
| how does sodium citrate work as an anticoagulant? |
|
Definition
| it halts clotting by removing calcium. |
|
|
Term
| how much blood is drawn into a blue top tube containing 0.3 ml of anticoagulant? |
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Definition
|
|
Term
| what method is used to avoid contact activation? |
|
Definition
| collect and store blood in plastic or siliconized glass tubes, to avoid contact with negatively charged surface |
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|
Term
| for how long is the coagulation sample stable if kept cool and capped? |
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Definition
|
|
Term
| when centrifuging blood for coagulation studies, what settings should be used and why? |
|
Definition
| 1500 rpm's, 15 min. to remove platelets |
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|
Term
| what tests are used to test for platelet function? |
|
Definition
| platelet count, bleeding time, platelet adhesion test, platelet aggregation tests, clot retraction |
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|
Term
| normal range for platelet count |
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Definition
|
|
Term
| what is the normal range for a bleeding time? |
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Definition
|
|
Term
| what kind of test is the aspirin tolerance test? |
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Definition
|
|
Term
| 3 methods of testing for plasma clotting proteins |
|
Definition
| clot endpoint, chromogenic assay, immunologic assay |
|
|
Term
| how are the results of a clot endpoint test read? |
|
Definition
| visually by tilting the tube |
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|
Term
| What method of coagulation testing uses electromagnetic field to detect movement of a metal ball? |
|
Definition
|
|
Term
| what method of coagulation testing measures the change in optical density when fibrin is formed? |
|
Definition
|
|
Term
| a quantitative and functional test of plasma clotting proteins |
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Definition
|
|
Term
| which coagulation test uses fluorescent dye? |
|
Definition
|
|
Term
| which method of coagulation testing uses antibodies to measure the quantity of factor present? |
|
Definition
|
|
Term
| does immunologic testing measure the functional or qualitative activity of the factor? |
|
Definition
|
|
Term
| What factors does the prothrombin time test for? |
|
Definition
| Factors II, V, VII, X, and fibrinogen |
|
|
Term
| which pathways are measured by the prothrobin time test (PT)? |
|
Definition
|
|
Term
| What is a normal result for Prothrombin Time (PT) test? |
|
Definition
|
|
Term
| What is in RecombiPlasTin Reagent? |
|
Definition
| recombinant human tissue factor, phospholipids, calcium chloride, buffer, preservative |
|
|
Term
|
Definition
| international normalized ratio |
|
|
Term
|
Definition
| patient's pt in seconds/mean normal pt in seconds, raised to ISI power |
|
|
Term
| where does the ISI, or international sensitivity index number come from? |
|
Definition
| supplied by manufacturer of thromboplastin reagents |
|
|
Term
| what does APTT stand for? |
|
Definition
| activated partial thromboplastin time |
|
|
Term
|
Definition
|
|
Term
| what test is a measure of fibrinogen concentration or anything that blocks thrombin? |
|
Definition
|
|
Term
| what is the normal range for Thrombin Time? |
|
Definition
|
|
Term
| what is a modified thrombin time test that uses commercial reference plasma? |
|
Definition
|
|
Term
| what is a quantitative and qualitative test used to determine fibrinogen concentration in mg/dl? |
|
Definition
|
|
Term
| what is the normal range for fibrinogen assay results, in mg/dl? |
|
Definition
|
|
Term
| two tests of the fibrinolytic system? |
|
Definition
|
|
Term
| In a D-dimer test or FDP assay, what would indicate a positive result? a negative result? |
|
Definition
| positive- rough edge. negative- smooth edge |
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