Term
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Definition
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Term
| Dorsal column -- medial lemniscus |
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Definition
| discriminative touch and conscious proprioception |
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Term
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Definition
| temperature, pain + crude touch |
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Term
| cuneocerebellar, dorsal and ventral tracts |
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Definition
| unconscious proprioception |
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Term
| name two additional fiber systems that ascend in the ALS |
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Definition
| spinoreticular (wakes you up when you are in pain) and spinomesencephalic fibers that travel to PAG to create feedback loop |
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Term
| all sensory cell bodies from neck down are where |
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Definition
| drg; central processes are 1st order axons that enter at the dorsal horn |
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Term
| muscle spindle afferent fiber (1) |
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Definition
| 1a; heavily myelinated; fastest; largest |
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Term
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Definition
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Term
delta fibers (3)
C fibers (4) |
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Definition
temperature and faster pain
temperature and slower pain |
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Term
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Definition
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Term
| describe spatial organization of Aa (1), Ab (2), Ad (3), and C (4) fibers incoming to the dorsal horn |
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Definition
| medial to lateral; the fibers are arranged by descending size (1,2,3,4). |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| conscious discriminative touch and conscious proprioception |
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Term
| fibers are added in what direction to dorsal column |
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Definition
| laterally; from bottom of spinal chord to top --> lower limb is added first and then trunk (medial to lower limb), etc.. |
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Term
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Definition
| trunk arm neck (medial to lateral); T6 ---> C6 |
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Term
| dorsal fasciculi end in what? |
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Definition
| the nucleus gracilis and nucleus cuneatus in the caudal medulla |
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Term
| fibers from gracilis and cuneatus nuclei in medulla decussate where? |
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Definition
| internal arcuate fibers; medial gracillis will become more ventral and cuneatus fibers will become more dorsal |
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Term
| describe medial lemniscus organization in rostral medulla |
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Definition
| Limbs Trunks Arms (ventral to dorsal; man standing up) |
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Term
| medial lemniscus shifts at medullopontine junction, describe this change in somatotopy |
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Definition
| LTA (ventral to dorsal) to LTA (lateral to medial (man lying down) |
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Term
| midbrain somatotopy of ML |
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Definition
| lateral in midbrain on way to thalamus goes from ATL (medial to lateral)--> ATL ventral to dorsal (flips little man upside down) |
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Term
| 3rd order neuron in VPL travel to where? |
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Definition
| sensory cortex in approp part of homunculus; reestablished organization of spinal cord LTA (lateral to medial) |
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Term
| When the ML is crossing midbrain to VPL, it passes in what orientation to the red nucleus? |
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Definition
| lateral to the red nucleus |
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Term
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Definition
| synapse in dorsal horn laminae 1- |
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Term
| Lesion in dorsal column or in nuclei |
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Definition
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Term
| above arcuate fibers to cortex lesions |
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Definition
| anesthesia will be contralateral |
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Term
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Definition
| dorsal column fibers preferentially degenerate; up to 20 years post infection; loss of dicriminative touch and loss of proprioception |
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Term
| cord hemisection -->Brown-Sequard Syndrome |
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Definition
| discriminative touch and conscious proprioception are lost opsilaterally from the lesion level down |
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Term
| unconscious proprioception to cerebellum is mediated by what 4 tracts |
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Definition
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Term
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Definition
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Term
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Definition
| DRG axon synapses in lateral dorsal horn, ipsilateral through Inferior Cerebellar Peduncle |
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Term
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Definition
| from DRG axon synapse in spinal border cells (gray c and ventral horn) --> these decussate through ventral white column and form vsct, condense in medulla, rostral pons/midbrain level they will enter superior cerebellum peduncle and decussate back to other side of cerebellum (2 crossings) |
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Term
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Definition
| synapse between DRG axon and cell bodies in Clarke's nucleus; C8 and up, DSCT goes through cuneocerebellar tract --> inferior cerebellar peduncle __. ipsilateral function |
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Term
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Definition
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Term
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Definition
| dorsal column/DSCT/VSCT degeneratie, robbing patient of proprioception |
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Term
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Definition
| masked clinically by paralysis; VSCT contralateral effect is minor |
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Term
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Definition
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Term
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Definition
| unmyelinated; pain and temperature |
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Term
| dorsolateral tract of Lissauer |
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Definition
| short fibered two way tract, where fibers diverge to different levels of cord |
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Term
| Ad and C synapse in what laminae |
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Definition
| 1 and 2 (marginal zone and subgelatinosa); decussate in ventral white commisure and collect in strip called anterolateral system |
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Term
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Definition
| crude touch pain temperature |
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Term
| lesion in ventral white commisure; e.g. syringomyelia |
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Definition
| bilateral affect; loss of pain and temperature; syringomyelia result in cape ditribution of pain and temperature loss (explain) |
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Term
| CT-guided electrode cordotomy |
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Definition
| is one method of pain control; try to disrupt pain pathway |
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Term
| describe organization of ALS |
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Definition
| lower limb more dorsal lateral and upper limb more ventral medial |
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Term
| where is ALS in brainstem |
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Definition
| dorsolateral tegmentum; converges with medial lemniscus in (pons??) |
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Term
| where does ALS synapse in diencephalon? |
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Definition
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Term
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Definition
| contralateral loss of pain and temperature sense at or below lesion level |
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Term
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Definition
| ipsilateral conscious touch and proprioception and contralateral loss of pain and temperature |
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Term
| anterior spinal arterfy infarct at T9 |
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Definition
| bilateral loss of pain and temperature around lower trunk |
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Term
| periaqueductal gray matter |
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Definition
| PAG --> NRM --> inhibit ALS; serotonin for NT |
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Term
| what receptors do PAG neurons have? |
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Definition
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Term
| direct inhibition of pain fibers |
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Definition
| inhibit the 1st order pain fiber synapses in dorsal horn as downward projection from reticulospinal system. |
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Term
| indirect inhibition of pain |
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Definition
| NRM descending fibers stimulate interneurons that inhibit ascending pain fibers via opiod receptors |
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Term
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Definition
| higher centers and spinomesenphalic tracts |
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Term
tabes dorsalis
May affect syphilis patients up to 20 years post infection |
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Definition
dorsal column fibers preferentially degenerate
May affect syphilis patients up to 20 years post infection |
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