Shared Flashcard Set

Details

Bacteriology
Bug Parade Bad Bugs
20
Biology
Graduate
03/25/2009

Additional Biology Flashcards

 


 

Cards

Term
Staph Aureus Apperance
Definition
Gram +
Cluster of cocci
Extracellular pathogen
Catalase + (distinguishable from strep)
Coagulase + (distinguishable from other staph)
Facultative anaerobe
Term
Staph Aureus Virulence
Definition
Surface Ag: sugar capsule: adherence to foreign objects, peptidoglycan, teichoic acid
Toxins: pore forming/dermonecrotic: alpha-hemolysis, beta-toxin, gamma-toxin, superAg, enterotoxins
Enzymes: staphylokinase: dissolves clots, penicillinase: dissolves antibiotics, DNAse, protease, lipase
Term
Staph Aureus Disease
Definition
Evasion of immune system: leukocidins and hemolysins: kill phagos, protein A: prevents opsonization and blocks Ab, catalase: resist respiratory burst
Attatch to surface proteins, produces toxins which causes tissue damage, boils, carbuncles, impetigo, pneumonia
Toxigenic disease: scalded skin syndrome, TSS (fever, rash, hypotension), food poisoning: enterotoxin, no organism necessary
Term
Staph Aureus Transmission
Definition
Wounds
Aerosol
Food poisoning
Term
Staph Aureus Reservoir
Definition
Normal flora of human anterior nares and skin
Term
Staph Aureus Treatment
Definition
Vancomycin
Penecillin-resistant
Term
Staph Aureus Medium
Definition
High salt media (MSA), forms yellow colonies
Term
Staph Aureus Control of Production
Definition
Cell-density dependent control, wait until lots before attacking
Agr D is sensed by Agr C and transduced into Arg A and activates RNA III
RNA III regualtes several virulence factors
Repressed: enterotoxin A, nucleases, hyaluronidase
Activated: all other toxins, adhesins, and enzymes
Term
Strep Pyogens Apperance
Definition
Gram +
Cocci in pairs/chains
Facultative anaerobe
Catalase -
Group A: beta-hemolytis, pyogenic, bacitractin-sensitive
Term
Strep Pyogens Virulence
Definition
Surface Ag: hyaluronic acid capsule (mucoid), M protein class I and II - rheumatic fever (class I), Lipoteichoic acid, proteins F and G, M-like proteins
Toxins: streptolysin O: O2-labile (anaerobic), streptolysin S: serum-depended
EnzymesL streptokinase, hyaluronidase, C5a peptidase, DNAses
Term
Strep Pyogens Disease
Definition
Direct infection: lipoteichoic acid binds fibronectin, M and F proteins bind closer for invasion, phagocytosis and opsonization are avoided, pharyngitis, tonsillitis, skin infections: impetigo, necrotizing fascitis
Toxin mediated: erythogenic toxin causes scarlet fever, TSS-like symptoms
Delayed immunologic rx: rheumatic fever (M protein I), glomerulonephritis
Term
Strep Pyogen Transmission
Definition
Contact
Aerosol
Term
Strep Pyogens Reservoir
Definition
Transient normal flora of human nasopharynx and skin
Term
Strep Pyogens Treat/Prev
Definition
Penicillin
Erythromycin
Term
Strep Pneumoniae Apperance
Definition
Gram + rod
Pyogenic
Catalase -
Facultative anaerobe
Alpha-hemolytic, bacitracin-resistant, optichin-sensitive
Term
Strep Pneumoniae Virulence
Definition
Pneumolysin encoded on lysogenic phage
Sugar capsule
Cell wall: peptidoglycan, teichoic acid
Neuraminidase
Secretory IgA protease
H2O2
Term
Strep Pneumoniae Disease
Definition
Pore-forming
Supress respiratory burst, antiphagocytic
Pneumonia
Sinusitis
Otitis media
Menigitis
Bacteremia
Term
Strep Pneumoniae Transmission
Definition
Aerosol
Term
Strep Pneumoniae Reservoir
Definition
URT
Term
Strep Pneumoniae Treat/Prev
Definition
Pencilin
Erythromycin
Vaconmycin
Vaccine: Pneumovax, Prevnar
Supporting users have an ad free experience!