Term
| short, curved gram neg pleo rods that stain poorly with warthin starry silver stain, aerobe (brown on yellow) |
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Definition
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Term
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Definition
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Term
| transmission of bartonella |
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Definition
| fleas, lice, sandflies (not ticks!) |
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Term
| cause vasoproliferative lesions (angiogenesis) and affect RBCs and vascular endothelial cells |
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Definition
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Term
| bartonella bacilliformis, quintana, hensalae - which are human specific? |
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Definition
| bacilliformis, quintana; henselae causes cat scratch disease |
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Term
| can infect at five-day intervals or persist in erythrocytes |
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Definition
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Term
| actin-rich structures that let bacteria invade - what is it called, what bacteria |
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Definition
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Term
| mechanism behind bartonella |
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Definition
| uses angiogenic factor/vascular endothelial growth factor (VEGF) to make new BVs, form vascular tumors |
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Term
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Definition
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Term
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Definition
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Term
| painless skin lesions that look like tumors in IC patients |
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Definition
| bacillary angimatosis (BA) from b. henselae |
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Term
| diseases caused by bartonella henselae in humans (IC, healthy) |
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Definition
| IC: peloisis (vascular lesions in liver or spleen), endocarditis; healthy: cat scratch disease, bacillary angiomatosis |
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Term
| life cycle of bartonella henselae |
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Definition
| cat not infected, flea bits cat and gives to another cat, cat scratches human |
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Term
| papule/pustule at inoculation site, fever, tired, headache, no bacteremia, large lymph nodes |
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Definition
| cat scratch disease (b. henselae in healthy people) |
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Term
| age, seasonality of b. henselae |
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Definition
| young adults, fall and early winter months, humid climate |
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Term
| abs are protective after you've gotten it |
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Definition
| cat scratch disease (b. henselae in healthy people) |
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Term
| complications of b. henselae |
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Definition
| parinaud's oculoglandular sydrome (self-limiting BV infection in eye); encephalitis/meningitis/myelitis (treat this!) |
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Term
| lesion in skin or organs that looks exactly like kaposi's sarcoma |
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Definition
| bacillary angiomatosis (b. henselae in IC patients or bartonella quintana) |
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Term
| tx for bacillary angiomatosis |
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Definition
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Term
| trench fever, endocarditis, chronic bacteremia; bacillary angiomatosis in IC patients |
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Definition
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Term
| transmission of bartonella quintana |
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Definition
| louse vector feces (pediculus humanus corporis) in dirty homeless alcoholics |
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Term
| bacillary angiomatosis diff presentation bt b. henselae and b. quintana |
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Definition
| b. quintana is more bone/subcutaneous |
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Term
| severe headache, pain in shin bones, high temperature in 5 day cycle |
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Definition
| trench fever (b. quintana) |
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Term
| biphasic disease in south american andes (peru, columbia, ecuador) |
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Definition
| carrion's disease (bartonella bacilliformis) |
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Term
| vector for bartonella bacilliformis |
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Definition
| sandfly (phlebotomus verracarum) |
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Term
| 2 phases of carrion's disease |
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Definition
| oroyo fever (anemia, pain in shins), verruga peruana (vasoproliferative eruptions of the skin) |
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Term
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Definition
| aminoglycosides - bacteriocidal; use erythro or doxy for henselae (except CSD) or quintana, chloro for bacilliformis |
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Term
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Definition
| PCR is best, can look for PCR product; elisa if you have to |
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Term
| 3 bugs than can cause ehrlichia in family anaplasmataceae |
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Definition
| erlichia chaffeensis (HME), ehrlichia ewingii, anaplasma phagocytophilum (HGE/HGA) |
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Term
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Definition
| anaplasma phagocytophilia, human granulocytic anaplasmosis |
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Term
| infects leukocytes (monocytes, granulocytes) (NOT RBCS) |
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Definition
| anaplasmatacae (phagocytophilum - granulocytes, e. chaffeensis - monocytes) |
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Term
| small gram - cocci, intracellular, no LPS or peptidoglycan |
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Definition
| anaplasmatacae (phagocytophilum, e. chaffeensis) |
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Term
| anaplasmatacae transmission |
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Definition
| ticks, wild rodents, deer |
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Term
| divide to form morulae (vacuole-bound colonies) |
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Definition
| anaplasmatacae (phagocytophilum, e. chaffeensis) |
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Term
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Definition
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Term
| lone star tick in arkansas, missouri, oklahoma, NC, SC, georgia in white tail deer |
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Definition
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Term
| not efficiently transmitted to egg, get infected at nymph stage post 1st deer bloodmeal |
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Definition
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Term
| trends for ehrlichia chafeensis |
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Definition
| old people, less fatality nowadays, june and july |
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Term
| wisconsin, minnesota, ct, ma, ny - infects neutrophils |
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Definition
| anaplasma phagocytophilium causing anaplasmosis (HGE/HGA) |
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Term
| transmitted by lxodes scapularis (blacklegged) |
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Definition
| lyme disease, HGE (can also be w. blacklegged lxodes pacificus) or babesia microti |
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Term
| HGA/HGE seasonality, age, fatality |
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Definition
| spring, summer; over 40 (diff than lyme!!!); less fatality |
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Term
| HME (e. chaffeensis) v. HGA (a. phagocytophilium) |
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Definition
| hme infects monocytes/macros; hga infects granulocytes |
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Term
| immune system dead (leukopenia, anemia), headache, rash (infrequent), fever, chills, myalgia, etc. |
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Definition
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Term
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Definition
| non-inflammatory uptake (no PG, LPS); do not fuse with lysosome, form morulae |
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Term
| might be biphasic like chlamydia |
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Definition
| a. phagocytophilum, e. chaffeensis |
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Term
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Definition
| morulae, indirect immunofluorescene assay, PCR (but treat based on sx, don't wait for this) |
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Term
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Definition
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Term
| the only parasite we know transmitted by lxodes scapularis/blacklegged tic |
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Definition
| babesiosis (b. duncani, b. divergens, b. microti) |
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Term
| lysis of RBCs, fever, sick - but not as severe as malaria |
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Definition
| babesiosis (b. duncani, b. divergens, b. microti) - so hopefully you have a spleen |
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Term
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Definition
| giemsa or wright stain of thin* blood smears; can do PCR (best) if travel, transplant |
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Term
| tetrads of replicating merozoites in cross-like pattern in a ring thing |
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Definition
| babesiosis (b. dunci, b. divergens, b. microti) |
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Term
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Definition
| azithro c-c-c-combo! Or clinda & guiine for SEEEkX WEEKS |
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